{"jobs":[{"absolute_url":"https://job-boards.greenhouse.io/vivodyne/jobs/4653123007","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4386465007,"location":{"name":"San Francisco (Brisbane), CA"},"metadata":null,"id":4653123007,"updated_at":"2025-12-20T15:51:26-05:00","requisition_id":"38","title":"AI Senior Scientist","company_name":"Vivodyne","first_published":"2025-02-14T14:48:26-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Vivodyne creates human data before clinical trials.\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;a href=\u0026quot;https://www.vivodyne.com\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;www.vivodyne.com\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;img src=\u0026quot;https://uploads-ssl.webflow.com/63ecc3195e0269612b3c70c2/65fb44cd6dd5597939714acf_job-posting-body-min%20(1).png\u0026quot; alt=\u0026quot;\u0026quot; width=\u0026quot;700\u0026quot; style=\u0026quot;max-width: 100%;\u0026quot;\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Role\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The AI Team at Vivodyne tackles some of the hardest and most interesting challenges in science and engineering. With access to extraordinarily feature-rich and massive-scale Vivodyne human tissue imagery, we are advancing the frontiers of artificial intelligence and its applications in biology. We are building a portfolio of AI technologies to automate the discovery, development, and de-risking of novel therapies using our unique technology platform, including single-cell 3D phenomics/machine vision, multimodal (multi-omic) translation, and reinforcement learning for robotic planning \u0026amp;amp; study design, among others.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As an \u0026lt;strong\u0026gt;AI Senior Scientist\u0026lt;/strong\u0026gt;, you will leverage your deep expertise in developing large-scale models (including Transformer, Diffusion, and hybrid architectures) and Generative AI solutions to help turn our state-of-the-art imaging and multi-omics datasets into groundbreaking scientific insights. You will collaborate closely with biologists, engineers, and AI specialists to deliver robust, production-ready algorithms and models that power Vivodyne’s high-impact discoveries.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;This role will be based on-site at our offices in Brisbane, California\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Scientific Innovation — \u0026lt;/strong\u0026gt;Work closely with internal and external stakeholders to understand their scientific objectives and innovate new approaches that utilize Vivodyne’s massive-scale imaging and multi-omics datasets.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Model Development — \u0026lt;/strong\u0026gt;Lead hands-on development of cutting-edge machine learning models (Transformers, Diffusion, hybrid architectures, etc.) with a focus on image processing, image enhancement, and Phenomap embeddings.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Data Pipeline Optimization — \u0026lt;/strong\u0026gt;Build and deploy pipelines capable of scaling to petabyte-scale data, ensuring robust MLOps practices on AWS or equivalent cloud platforms.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Multimodal Integration — \u0026lt;/strong\u0026gt;Explore and develop novel methods to incorporate multi-omics data into imaging-based Phenomaps, advancing the state of the art in multimodal phenotypic analysis.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; Communication — \u0026lt;/strong\u0026gt;Partner with tissue engineers, microfluidics experts, and robotics engineers to refine data collection strategies, provide feedback on imaging system performance, and identify opportunities for improved AI-driven solutions.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Scientific Rigor \u0026amp;amp; Leadership —\u0026lt;/strong\u0026gt;\u0026amp;nbsp;Uphold scientific excellence through peer reviews, proper documentation, and clear communication. Drive a culture of continuous improvement, best practices, and adherence to rigorous research methodologies.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Scalability \u0026amp;amp; Efficiency —\u0026lt;/strong\u0026gt;\u0026amp;nbsp;Emphasize modularity, composability, and performance efficiency in designing and implementing high-throughput compute and analytics pipelines.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Domain \u0026amp;amp; Technical Growth — \u0026lt;/strong\u0026gt;Remain current with the latest research trends in Generative AI, biomedical imaging, cloud computing, and data-intensive training. Proactively share knowledge and mentor teammates to foster overall organizational expertise.\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Requirements and Expectations\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Scientific Excellence — \u0026lt;/strong\u0026gt;Stay current with AI/ML research, especially in Generative AI, Transformers, Diffusion models, and multi-modal architectures. Apply rigorous, data-driven methods for sound outcomes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Hands-On Leadership — \u0026lt;/strong\u0026gt;Set high standards for model development and code quality, mentoring team members and fostering innovation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Accountability — \u0026lt;/strong\u0026gt;Own model and infrastructure development from concept to deployment, delivering reliable, scalable solutions aligned with Vivodyne’s mission.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Problem Solving \u0026amp;amp; Adaptability — \u0026lt;/strong\u0026gt;Develop creative solutions to novel research challenges, thriving in a fast-paced, dynamic startup environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; Communication — \u0026lt;/strong\u0026gt;Work cross-functionally to align AI strategies with business goals, ensuring clear communication and consensus-building.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Delivering Results — \u0026lt;/strong\u0026gt;Prioritize impactful research, using project management best practices to track progress, mitigate risks, and meet deadlines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Architecture \u0026amp;amp; Coding — \u0026lt;/strong\u0026gt;Design scalable, cost-effective systems and produce clean, well-documented code with continuous testing and governance compliance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Resource Optimization — \u0026lt;/strong\u0026gt;Apply financial discipline to maximize the efficiency of compute, storage, and third-party services.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Team \u0026amp;amp; Thought Leadership — \u0026lt;/strong\u0026gt;Foster an inclusive environment, mentoring future leaders and representing Vivodyne in AI research and industry discussions.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Education \u0026amp;amp; Experience\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Computer Science, Applied Mathematics, or a related field, or equivalent practical experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven expertise developing and deploying advanced ML architectures (Transformers, Diffusion, multi-modal models) in Generative AI settings.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated history of success with image processing and large-scale model training.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Technical Skills\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Strong knowledge of AWS or another major cloud provider for MLOps, big data processing, and scalable computing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience building models for petabyte-scale datasets and understanding the associated architectural and operational complexities.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Domain Expertise (Preferred)\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with biological or biomedical imaging; advanced knowledge in multi-modal Phenomaps, especially integrating imagery with multi-omics data, is a major plus.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Additional Desired Skills\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Prior experience with HPC, GPU clusters, or distributed computing frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable with container orchestration and open-source data engineering/ML frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Soft Skills \u0026amp;amp; Leadership\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Strong written and oral communication skills, with a proven ability to present complex technical topics to non-experts.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to thrive in ambiguous environments, driving clarity and direction with minimal supervision.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$220,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$270,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4036089007,"name":"AI + Data Science","child_ids":[],"parent_id":4036084007}],"offices":[{"id":4044173007,"name":"San Francisco (Brisbane)","location":"San Francisco, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/vivodyne/jobs/5137539007","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4632329007,"location":{"name":"San Francisco (Brisbane), CA"},"metadata":null,"id":5137539007,"updated_at":"2026-05-19T09:56:29-04:00","requisition_id":"54","title":"Associate Scientist","company_name":"Vivodyne","first_published":"2026-05-19T09:56:29-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Vivodyne creates human data before clinical trials.\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;a href=\u0026quot;https://www.vivodyne.com\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;www.vivodyne.com\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;img src=\u0026quot;https://uploads-ssl.webflow.com/63ecc3195e0269612b3c70c2/65fb44cd6dd5597939714acf_job-posting-body-min%20(1).png\u0026quot; alt=\u0026quot;\u0026quot; width=\u0026quot;700\u0026quot; style=\u0026quot;max-width: 100%;\u0026quot;\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Role\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;This is a \u0026lt;strong\u0026gt;full-time, onsite role\u0026lt;/strong\u0026gt; in San Francisco. This role is a \u0026lt;strong\u0026gt;shifted schedule\u0026lt;/strong\u0026gt; (Tuesday-Saturday or Sunday-Thursday).\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will be an integral member of the Bioengineering team, supporting the development and operation of advanced human tissue models for therapeutic discovery and translational research. This role is ideal for a highly motivated experimental scientist who enjoys working at the intersection of biology, engineering, and automation in a fast-paced R\u0026amp;amp;D environment.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will work closely with scientists, engineers, roboticists, and software teams to support large-scale tissue culture workflows, execute routine and specialized assays, and help maintain reliable operation of automated tissue culture systems. The ideal candidate is hands-on, adaptable, detail-oriented, and excited to learn new technologies and experimental approaches.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role requires flexibility, strong experimental rigor, and comfort operating in a highly collaborative environment with evolving priorities and workflows.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Tissue Culture \u0026amp;amp; Experimental Support\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Support routine expansion, maintenance, and characterization of primary human cell cultures using aseptic technique.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assist with 3D tissue seeding, maintenance, feeding, harvesting, and downstream processing workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Execute routine molecular and cellular assays including ELISAs, flow cytometry, cell digestions, fixations, staining workflows, and sample preparation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support tissue characterization workflows including imaging, cytokine analysis, and functional assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain accurate experimental records and documentation using electronic lab notebooks and SOPs.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Automation \u0026amp;amp; Platform Operations\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Train as an operator for automated tissue culture and experimental workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Monitor and supervise automated workflows during scheduled operating windows, including occasional non-standard shifts (e.g. evening shifts or one weekend day).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Interface closely with robotics and hardware teams to troubleshoot workflow issues and improve platform reliability.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assist in validating and optimizing automated protocols for scalability and reproducibility.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Cross-Functional Collaboration\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Collaborate closely with scientists across bioengineering, biology, automation, and computational teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Communicate experimental progress, issues, and observations clearly and proactively.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to process improvement initiatives and support development of scalable laboratory workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Help maintain laboratory organization, inventory, and operational readiness.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Growth \u0026amp;amp; Development\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Learn and adopt new experimental techniques, instrumentation, and automation workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to a culture of scientific rigor, curiosity, adaptability, and continuous improvement.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Participate in troubleshooting and problem-solving for experimental and operational challenges.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Requirements and Expectations\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree in bioengineering, biology, physiology, genetics, biochemistry, or a related life sciences field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;1-3 years of prior experience in industry.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with sterile mammalian cell culture techniques.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with standard wet-lab molecular and cellular biology assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong organizational skills and attention to detail in experimental execution and documentation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable working in a fast-paced, highly collaborative research environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Willingness to work flexible schedules as needed to support automated experimental workflows after training is completed.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Preferred Experience\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Masters degree is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with primary human cells and/or 3D cell culture systems such as organoids, spheroids, or organ-on-chip platforms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with assays such as ELISA, flow cytometry, immunostaining, or fluorescence imaging.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exposure to automated laboratory systems, liquid handling robotics, or high-throughput workflows is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with laboratory data analysis and visualization tools.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What We’re Looking For\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Highly motivated and intellectually curious individuals who are excited to learn quickly and take ownership.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong experimental instincts and willingness to support a wide variety of laboratory activities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Someone who thrives in dynamic environments and can adapt as priorities evolve.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Interest in the convergence of biology, automation, robotics, and AI-enabled experimentation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A collaborative teammate who communicates clearly and works effectively across disciplines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A practical problem-solver who is dependable, resourceful, and eager to contribute wherever needed.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Why Vivodyne?\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;High-Impact Mission\u0026lt;/strong\u0026gt; — Play a foundational role in transforming drug discovery through computational biology applied to the richest human tissue datasets in existence.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Method, Not Just Application\u0026lt;/strong\u0026gt; — You won\u0026#39;t just run pipelines. You\u0026#39;ll decide what pipelines should exist, whether they\u0026#39;re working, and what should replace them.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Multi-Disciplinary Exposure\u0026lt;/strong\u0026gt; — Work alongside experts in robotics, AI, tissue engineering, and microfluidics in a deeply cross-functional setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Growth Opportunities\u0026lt;/strong\u0026gt; — A fast-growing startup with significant autonomy, ownership, and direct influence over the biological data infrastructure and analytical strategy.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$95,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$135,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4017629007,"name":"Biology \u0026 Bioengineering","child_ids":[],"parent_id":4036086007}],"offices":[{"id":4044173007,"name":"San Francisco (Brisbane)","location":"San Francisco, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/vivodyne/jobs/4997562007","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4566497007,"location":{"name":"San Francisco (Brisbane), CA"},"metadata":null,"id":4997562007,"updated_at":"2025-12-20T15:52:33-05:00","requisition_id":"46","title":"Principal Mechanical Engineer – Advanced Automation \u0026 Systems Integration","company_name":"Vivodyne","first_published":"2025-12-04T08:54:00-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Vivodyne creates human data before clinical trials.\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;a href=\u0026quot;https://www.vivodyne.com\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;www.vivodyne.com\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;img src=\u0026quot;https://uploads-ssl.webflow.com/63ecc3195e0269612b3c70c2/65fb44cd6dd5597939714acf_job-posting-body-min%20(1).png\u0026quot; alt=\u0026quot;\u0026quot; width=\u0026quot;700\u0026quot; style=\u0026quot;max-width: 100%;\u0026quot;\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Role\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As a Principal Mechanical Engineer at Vivodyne, you will be part of a multi-disciplinary team pushing the boundaries of automated, large-scale \u0026quot;organ-on-a-chip\u0026quot; robotics and related manufacturing systems. Your focus will be on developing and optimizing hardware and software that orchestrates robotic arms, embedded controllers, and microfluidic systems to enable high-throughput, high-precision biological workflows.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role requires expertise across hardware and software, but primarily hardware.\u0026amp;nbsp; From high-level motion control and machine vision to robotics programming and embedded firmware. You’ll work extensively with existing Python (less so with, C#, and C++) codebases, ensuring seamless system integration and performance.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You are a mechanical design expert.\u0026amp;nbsp; Things like kinematic docking, 440 vs 316, FEA, and error budgets are very familiar to you.\u0026amp;nbsp; Your friends include McMaster-Carr, Misumi, and Grainger.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Collaboration is key—you’ll engage with mechanical engineers, biologists, immunologists, AI scientists, and process engineers to design and refine automation workflows that drive breakthroughs. We’re looking for a problem solver comfortable working across multiple domains, thriving in a fast-paced, high-innovation environment that values continuous learning and technical excellence.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a full-time, onsite role in San Francisco, where you’ll be designing, building, and testing some of the most advanced automation and high-throughput biology systems in the world.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Architect, design, and implement advanced automation systems, ranging from automated microfluidic manufacturing to high-precision mammalian cell culture platforms—all of which are mission-critical and highly visible both internally and externally.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop hardware and software systems that acquire and process data reliably, ensuring smooth handoffs to production through rigorous documentation, data acquisition, and analysis.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace the dynamic nature of a rapidly growing startup, working across multiple projects and disciplines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate cross-functionally with Product leads, tissue engineers, microfluidics specialists, and AI researchers etc. to gather requirements, set technical objectives, and integrate new features into our robotics platforms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and implement resilience mechanisms to ensure system robustness, enabling fault detection, fault recovery, and minimal downtime, while maintaining data integrity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proactively identify optimization opportunities, selecting priorities through engineering analysis and data-driven decision-making.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Communicate progress and findings to internal stakeholders—including mechanical engineers, data scientists, and senior leadership—through data-laden presentations and technical reports.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Requirements and Expectations\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h4\u0026gt;Technical Expertise \u0026amp;amp; Knowledge\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree (M.S. or Ph.D. preferred) in Mechanical Engineering, Chemical Engineering, or a related field with a focus on microfluidics, tissue engineering, or lab automation at least six years of directly relevant industry experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Broad experience in hardware and, preferable, software design for automation, spanning off-the-shelf solutions and custom-built systems—you have developed complex automation workflows for production-level environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in key hardware and software tools, including SolidWorks (expert-level, CAM experience is a plus), and at some exposure to Python/Matlab/C++/C#/Javascript/etc.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with commonly used automation hardware, such as vision/camera systems (optics and/or optomechanical expertise is a plus), motion control, liquid handling, and pick-and-place robotics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Highly knowledgeable in various Manufacturing Technologies, you know how things are made and which approaches fit a particular application\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Industry-specific expertise is highly valued:\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Biotech/lab automation or semiconductor robotics experience is a strong advantage.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of microfluidics and fluid handling systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience integrating robotics with high-content imaging and confocal microscopy systems, optimizing workflows for advanced imaging pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Biology background or familiarity with cell and tissue engineering concepts is a significant plus, especially in handling biological samples.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;Bonus points for experience with:\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Electronics/PCBA design or basic knowledge (reading schematic, troubleshooting interconnects), statistical analysis/data collection to inform design performance rigorously\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;Problem Solving \u0026amp;amp; Ownership\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;You take an outcome-driven approach, translating project goals and technical challenges into systematic, resilient robotics solutions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong ownership mentality, ensuring the timely delivery of high-reliability features and improvements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Growth-oriented, continuously seeking ways to enhance automation processes, optimize robotic operations, and drive innovation.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;Collaboration \u0026amp;amp; Communication\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;A team player, capable of working with engineers, scientists, and external stakeholders to define requirements, refine designs, and communicate project progress effectively.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Clear communicator, able to explain complex robotics concepts to cross-functional teams, from software engineers to biologists.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Interdisciplinary mindset, integrating feedback from various fields to develop thoughtful, iterative design improvements.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;Innovation \u0026amp;amp; Leadership Mindset\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Passionate about staying at the cutting edge of robotics, bringing fresh ideas from emerging technologies, best practices, and research to the team.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable taking initiative in uncharted territories, whether it’s developing new motion-planning algorithms or integrating novel sensors and hardware.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h1\u0026gt;Why Vivodyne?\u0026lt;/h1\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;High-Impact Mission – Play a pivotal role in transforming drug discovery and human therapeutics through advanced robotics and automation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Multi-Disciplinary Exposure – Work alongside leading experts in robotics, AI, biology, and microfluidics, expanding your expertise in a truly collaborative setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Growth Opportunities – A fast-growing startup environment with significant autonomy, ownership, and influence over best practices in the intersection of biotech and robotics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Innovative Culture – Join a team that prioritizes continuous learning, rigorous engineering and scientific standards, and bold problem-solving.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;If you\u0026#39;re excited about revolutionizing automation in organoid engineering and biotech—while pushing the boundaries of robotics, AI, and advanced systems—let’s connect! Please submit your resume and a brief statement of interest. We look forward to exploring the opportunity together.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$221,900\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$308,100 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4017627007,"name":"Hardware + Automation","child_ids":[],"parent_id":4036084007}],"offices":[{"id":4044173007,"name":"San Francisco (Brisbane)","location":"San Francisco, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/vivodyne/jobs/5096737007","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4612927007,"location":{"name":"San Francisco (Brisbane), CA"},"metadata":null,"id":5096737007,"updated_at":"2026-04-24T17:03:14-04:00","requisition_id":"52","title":"Senior Bioinformatician","company_name":"Vivodyne","first_published":"2026-04-01T16:30:56-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Vivodyne creates human data before clinical trials.\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;a href=\u0026quot;https://www.vivodyne.com\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;www.vivodyne.com\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;img src=\u0026quot;https://uploads-ssl.webflow.com/63ecc3195e0269612b3c70c2/65fb44cd6dd5597939714acf_job-posting-body-min%20(1).png\u0026quot; alt=\u0026quot;\u0026quot; width=\u0026quot;700\u0026quot; style=\u0026quot;max-width: 100%;\u0026quot;\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Role\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Software \u0026amp;amp; Data Science team at Vivodyne tackles some of the hardest problems at the intersection of human biology, large-scale data, and machine learning using uniquely rich imaging and multi-omics datasets from lab-grown human tissues.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are expanding our capabilities to generate high-throughput -omics data across automated human tissue models, with a primary focus on single-cell and bulk transcriptomics, secretomics, and proteomics. We\u0026#39;re looking for a Bioinformatician who can develop new analytical methods and build robust infrastructure to support them at scale.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will define how we process, store, integrate, and interpret biological datasets, making foundational decisions that shape the long-term utility of our data for internal research, AI/ML model development, and external partners. This means owning both the science (what question does this analysis answer, and how defensible is the conclusion?) and the engineering (does this pipeline run reliably at scale, and can someone else extend it?).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a high-impact, cross-functional role. You\u0026#39;ll sit within the Software \u0026amp;amp; Data Science organization and collaborate daily with experimental biologists, AI/ML researchers, software engineers, and client-facing teams.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a \u0026lt;strong\u0026gt;full-time, onsite role\u0026lt;/strong\u0026gt; in San Francisco.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Develop and Own Analytical Methods\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design, implement, and critically evaluate computational approaches for scRNA-seq, bulk RNA-seq, secretomics, and proteomics data including QC, normalization, batch correction, dimensionality reduction, clustering, differential expression, trajectory analysis, and multi-dataset integration.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Go beyond applying standard tools: develop or adapt methods for perturbation modeling, causal inference, network reconstruction, ligand-receptor inference, and multi-omics integration as the science demands.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Select and standardize tooling based on rigorous benchmarking, not convention. Challenge default choices when the data or use-case warrants it.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Build Scalable, Production-Grade Pipelines\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Architect end-to-end analysis workflows in Python and/or R using modern workflow orchestration (Nextflow, Snakemake, or equivalent) that are reproducible, version-controlled, and designed to run at the scale of tens to hundreds of thousands of samples.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with software and data engineers to productionize pipelines, ensure robust data ingestion and storage, and contribute to decisions on biological data architecture (storage formats, schema design, long-term data usability).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Write well-documented, testable code that other engineers and scientists can run, review, and extend.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Drive Biological Insight and Interpretation\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Own dataset analysis to answer biological and client-driven questions with rigor. Ground conclusions in the limits of the data and clearly communicate what can and cannot be concluded with confidence.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with experimental biologists to frame the most relevant biological questions, design analyses, and recommend experiments and data-generation strategies to fill key gaps.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Produce publication-quality figures, internal reports, and partner-facing deliverables that are decision-useful.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Shape Data Strategy\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Help define benchmarking strategies for internal tissue model development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proactively identify opportunities to leverage internal and public datasets to accelerate scientific progress.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to decisions around data standards, comparability, and the integration of omics features into downstream ML models and AI workflows.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Communicate Across Functions\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Translate complex multi-omic analyses into clear insights for biologists, AI/ML researchers, software engineers, and non-technical stakeholders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Tailor depth and framing to the audience while maintaining scientific rigor.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Requirements and Expectations\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Technical Expertise\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. in Computational Biology, Bioinformatics, Genomics, Systems Biology, Biostatistics, or a related quantitative field with deep focus on transcriptomics and/or proteomics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;2–5 years of post-PhD experience; some industry experience strongly preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong, hands-on proficiency in Python for bioinformatics (Scanpy and the broader scverse ecosystem in particular) with the judgment to know when existing tools are insufficient and the skill to build alternatives. Familiarity with R-based workflows (Seurat, Bioconductor, Monocle) is valued as evidence of breadth, but Python is the production language.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep experience with scRNA-seq datasets and workflows, including QC, batch correction, clustering, differential expression, annotation, and integration across experiments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with proteomics or secretomics analysis (Olink or similar high-dimensional panels), including normalization and cross-modality integration with transcriptomic profiles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfort in a Unix/Linux environment with standard dev tools (git, containers, CI/CD); experience with cloud environments (AWS) and workflow managers is a strong plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with data infrastructure for large-scale biological data (e.g., AnnData/H5AD, TileDB-SOMA, or similar) is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Problem Solving \u0026amp;amp; Ownership\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ability to independently structure and execute complex analytical projects from ambiguous initial questions to concrete, reviewable outputs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong biological intuition for distinguishing meaningful signal from artifact and the discipline to validate before interpreting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable navigating ambiguity in a fast-moving startup; can prioritize, make trade-offs, and hit agreed timelines.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; Communication\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Excellent written and verbal communication; able to explain computational methods and biological implications to biologists, engineers, and non-technical stakeholders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to collaborate across disciplines.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Innovation \u0026amp;amp; Leadership\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Track record of taking omics analyses from raw data to figures/tables suitable for publications, reports, or decision meetings.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to manage multiple analyses in parallel and ship work on predictable timelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;History of method development or meaningful adaptation of existing methods to novel data types or experimental designs.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Preferred Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with multi-modal data integration (e.g., combining imaging, transcriptomics, and proteomics features).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Background in drug discovery, toxicology, or translational research where multi-omic data inform therapeutic decisions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with representation learning or ML for biological data (embeddings for cells, genes, or proteins), especially in collaboration with ML specialists.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with organoids, primary tissues, or organ-on-chip systems.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$214,400\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$245,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4036089007,"name":"AI + Data Science","child_ids":[],"parent_id":4036084007}],"offices":[{"id":4044173007,"name":"San Francisco (Brisbane)","location":"San Francisco, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/vivodyne/jobs/5120631007","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4624156007,"location":{"name":"San Francisco (Brisbane), CA"},"metadata":null,"id":5120631007,"updated_at":"2026-04-24T17:10:41-04:00","requisition_id":"53","title":"Senior Full Stack Software Engineer","company_name":"Vivodyne","first_published":"2026-04-24T17:09:48-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Vivodyne creates human data before clinical trials.\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;a href=\u0026quot;https://www.vivodyne.com\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;www.vivodyne.com\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;img src=\u0026quot;https://uploads-ssl.webflow.com/63ecc3195e0269612b3c70c2/65fb44cd6dd5597939714acf_job-posting-body-min%20(1).png\u0026quot; alt=\u0026quot;\u0026quot; width=\u0026quot;700\u0026quot; style=\u0026quot;max-width: 100%;\u0026quot;\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Role\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We’re looking for an exceptional Senior Full-Stack Software Engineer to work hand in hand with our Product team to build polished, high-performance web applications using React with FastAPI on the backend and Postgres as a database.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The ideal candidate leads with deep frontend expertise in building sophisticated, stateful UIs in React/TypeScript, while bringing enough backend fluency to own features end-to-end. You\u0026#39;ll build rich, data-dense interfaces for scientific workflows where getting the interaction design and state management right is the hard part. Additionally, the ideal candidate is an \u0026#39;AI native\u0026#39; and uses their strong technical expertise to augment the prototyping speed provided by LLMs. You\u0026#39;ll ship deliverables in days, not months, and have a sharp instinct for system architectures that achieve rapid delivery and robust performance.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will be a core contributor to shaping our next-generation biotech platform that discovers and tests new drugs on lab-grown human tissues.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Own the building of scientific experiment design and results-monitoring tools that, together with our platform, have enabled Vivodyne to partner with a majority of the top-10 pharmaceutical companies in making better, safer cures to complex human diseases. You will be expected to deliver web applications that align with well-designed frames/user flows and product requirements that help scientists interact seamlessly with our unique datasets, robotic systems, and lab-grown tissues.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You’ll have the opportunity to work at the cutting edge of biotech and software engineering, collaborating with teams spanning tissue engineering, robotics, and AI. You\u0026#39;ll be working a few feet away from large precision robots, laser microscopes, and robot arms, surrounded by an exceptionally talent-dense team of experts from multiple scientific disciplines.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will be able to focus on building internal products and tools with incredible functionality, surrounded by sophisticated end users directly appreciative of the products you build---without needing to do integration testing for first-gen Chromebooks or handle bug reports from Fire tablets.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;While bringing a passion and exquisite skill for building and shipping high-quality applications that drive scientific discovery, you\u0026#39;ll be involved firsthand in the advancement of human health, you\u0026#39;ll watch thousands of human organ tissues grow before your eyes, and join an intense, fun, fast-moving team in shaping the future of human health.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Frontend-Led Full-Stack Development\u0026lt;/strong\u0026gt; — Architect and build complex React/TypeScript interfaces for scientific workflow applications; own backend integration points via API design and data layer work in Postgres.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;User Experience\u0026lt;/strong\u0026gt; — Create clean, responsive, and user-focused interfaces that translate complex requirements into intuitive designs, establishing best practices for component architecture and state management patterns.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Code Quality \u0026amp;amp; Best Practices\u0026lt;/strong\u0026gt; — Write well-tested, maintainable code with a focus on scalability, performance, and cost-efficiency.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; Communication\u0026lt;/strong\u0026gt; — Work closely with scientists, engineers, and AI researchers to gather requirements, provide updates, and deliver impactful solutions.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;High Velocity / AI Accelerated Development\u0026lt;/strong\u0026gt; — Leverage leading language models and agentic tools like Claude Code and Codex, or similar to ship reliable code quickly; maximize prototyping and component design velocity while balancing robustness of implementations\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Requirements and Expectations\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h3\u0026gt;Technical Excellence\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise in React, TypeScript, and modern frontend architecture (component composition, state management, performance profiling).\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficient in building visually appealing, high-performance React applications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong CSS/styling architectural skills (CSS modules, Tailwind etc.)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong data modeling skills for biotech applications, translating scientific needs into structured schemas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable in API design, schema definition, and query optimization with Postgres.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Solid foundation in data structures, algorithms, and software architecture (CS degree preferred).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;Accountability \u0026amp;amp; Problem-Solving\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Own full-stack development, ensuring high-quality, tested, and timely feature delivery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Balance speed and rigor to solve complex engineering challenges, from large-scale data ingestion to optimizing imagery metadata.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;Collaboration \u0026amp;amp; Communication\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Work cross-functionally with scientists, engineers, and AI researchers, aligning technical solutions with user needs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Keep end-users in mind, delivering intuitive, efficient workflows.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;Delivering Results\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Manage time effectively, handling multiple priorities while shipping production-ready features.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Champion best practices, maintain clear documentation, and uphold high coding standards.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;Architecture \u0026amp;amp; Design\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design scalable, reliable systems while anticipating and addressing bottlenecks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leverage open-source and existing frameworks to optimize development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;Leadership \u0026amp;amp; Influence\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Mentor junior engineers through code reviews and knowledge sharing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Advocate for full-stack best practices to drive scientific and business impact.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s or Master’s in Computer Science (or related field), or equivalent experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;5+ years building complex React applications with sophisticated state management, not just simple CRUD interfaces.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Fluency in TypeScript. Knowledge of TanStack ecosystem is a bonus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience Developing Applications that Render and Annotate Imagery is highly valued.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable working with APIs and understanding the data layer.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of Python (e.g. Pydantic, FastAPI).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of Postgres in production environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in High-throughput Laboratory Automation or Robotics is highly valued.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent Communication Skills for conveying technical concepts and aligning stakeholder expectations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Project Delivery Experience in fast-paced environments; comfortable balancing shifting priorities and multiple projects.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven Ability to collaborate across disciplines, from biology to automation to AI, delivering high-impact results.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track Record of shipping secure, maintainable, and well-tested code.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$204,400\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$285,600 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4017628007,"name":"Software","child_ids":[],"parent_id":4036084007}],"offices":[{"id":4044173007,"name":"San Francisco (Brisbane)","location":"San Francisco, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/vivodyne/jobs/5141418007","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4634135007,"location":{"name":"San Francisco (Brisbane), CA"},"metadata":null,"id":5141418007,"updated_at":"2026-05-19T09:56:52-04:00","requisition_id":"55","title":"Senior Scientist","company_name":"Vivodyne","first_published":"2026-05-19T09:56:52-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Vivodyne creates human data before clinical trials.\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;a href=\u0026quot;https://www.vivodyne.com\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;www.vivodyne.com\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;img src=\u0026quot;https://uploads-ssl.webflow.com/63ecc3195e0269612b3c70c2/65fb44cd6dd5597939714acf_job-posting-body-min%20(1).png\u0026quot; alt=\u0026quot;\u0026quot; width=\u0026quot;700\u0026quot; style=\u0026quot;max-width: 100%;\u0026quot;\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Role\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;This is a \u0026lt;strong\u0026gt;full-time, onsite role\u0026lt;/strong\u0026gt; in San Francisco.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will lead the development, optimization, and scaling of advanced human tissue models for therapeutic discovery at Vivodyne. This role is focused on building robust, biologically faithful in vitro tissue systems that generate actionable data and can be deployed reproducibly at scale within Vivodyne’s automated experimental platform.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a Senior Scientist on the Bioengineering team, you will own a scientific program centered around a specific tissue system or disease model (e.g. liver, lung, gut), driving projects from early biological hypothesis generation through mature, scalable workflows suitable for high-throughput experimentation and therapeutic evaluation.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will work cross-functionally with bioengineers, computational biologists, AI scientists, roboticists, hardware engineers, and translational researchers to develop next-generation human tissue platforms that enable deeper understanding of human biology and drug response.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role requires exceptional experimental rigor, deep technical expertise in complex cell culture systems, strong scientific reasoning, and the ability to make sound, data-driven decisions in ambiguous and fast-moving environments. We are looking for a scientist who combines deep biological intuition with disciplined execution and who consistently designs experiments that produce clear, actionable conclusions.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Tissue Model Development\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead development and optimization of complex in vitro human tissue models using primary human cells and advanced 3D culture systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design, execute, and interpret experiments to improve tissue phenotype, stability, scalability, reproducibility, and biological relevance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop healthy and disease-state tissue models across multiple organ systems and therapeutic areas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive mechanistic understanding of tissue behavior through multimodal characterization approaches.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Experimental Leadership\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Independently design rigorous experimental strategies with clear success criteria, controls, and actionable outcomes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Generate high-quality datasets using approaches including confocal imaging, transcriptomics, proteomics, flow cytometry, and functional assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyze and synthesize complex biological data to guide model optimization and program direction.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Troubleshoot difficult experimental problems systematically using first-principles reasoning and quantitative analysis.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish and refine SOPs and experimental workflows suitable for scalable automated execution.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Platform Scaling \u0026amp;amp; Automation\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Partner closely with robotics and hardware teams to adapt tissue workflows for automated operation and large-scale experimentation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support transfer of tissue models from exploratory R\u0026amp;amp;D into reliable production-grade workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify sources of experimental variability and implement strategies to improve robustness and reproducibility.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to the development of scalable assay and tissue characterization pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Cross-Functional Collaboration\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Serve as a scientific lead and subject matter expert for tissue biology programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Interface closely with AI, computational biology, software, automation, and translational science teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Present experimental findings clearly and effectively to internal leadership and external collaborators.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mentor junior scientists and contribute to building a culture of scientific rigor, operational excellence, and world class experimentation.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Scientific Documentation \u0026amp;amp; Operational Excellence\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Maintain meticulous experimental records, protocols, analyses, and decision rationale.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure experimental conclusions are reproducible, well-supported, and operationally actionable.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to internal scientific standards for data quality, assay validation, and experimental design.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive continuous improvement of workflows, assays, and organizational scientific practices.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Requirements and Expectations\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in bioengineering, cell biology, molecular biology, physiology, developmental biology, genetics, or a related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;2–4 years of industry experience following PhD and/or postdoctoral training in biotechnology, therapeutics, tissue engineering, or related fields.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated record of scientific achievement through high-impact publications, patents, awards, or other evidence of advancing the state of the art in your field.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise in mammalian cell culture, including primary human cells and complex 3D tissue models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Extensive hands-on experience designing and executing sophisticated in vitro experiments with strong experimental controls and reproducibility.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise with modern biomolecular and cellular characterization techniques including:\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;confocal imaging,\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;flow cytometry,\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;transcriptomic workflows,\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;proteomic assays,\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;next-generation sequencing workflows,\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;and interpretation of resulting datasets.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;Mastery of experimental design, assay development to fit experimental needs, and quantitative biological analysis.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to independently drive complex technical programs in fast-paced R\u0026amp;amp;D environments.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Preferred Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience developing organoid, organ-on-chip, or microphysiological systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience scaling biological workflows into automated or high-throughput systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with multimodal datasets integrating imaging, transcriptomics, proteomics, and functional readouts.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with computational analysis tools for biological data interpretation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience supporting translational, preclinical, or therapeutic discovery programs.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What We’re Looking For\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Scientific Judgment\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;p\u0026gt;You design experiments with intent. You understand how to distinguish signal from noise, identify the critical question, and execute the next experiment that most efficiently moves a program forward. You are rigorous, skeptical, and deliberate in your reasoning, and you hold a high standard for experimental quality and interpretation.\u0026lt;/p\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Experimental Excellence\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;p\u0026gt;You are an exceptional experimentalist with deep technical fluency and strong laboratory instincts. You understand the importance of controls, reproducibility, assay validation, and operational precision alongside speed. You can troubleshoot complex biological systems systematically and efficiently.\u0026lt;/p\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Ownership \u0026amp;amp; Execution\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;p\u0026gt;You take ownership of programs and outcomes. You are highly organized, reliable, and capable of managing multiple priorities while maintaining scientific quality and attention to detail. You understand that excellent science requires both creativity and disciplined execution.\u0026lt;/p\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; Communication\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;p\u0026gt;You communicate clearly, document thoroughly, and work effectively across disciplines. You can explain complex biological concepts to engineers, computational scientists, and leadership teams while incorporating feedback from diverse stakeholders.\u0026lt;/p\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Adaptability \u0026amp;amp; Focus\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;p\u0026gt;You remain thoughtful and effective in dynamic environments. You can tune out noise, prioritize effectively, and maintain focus on the highest-value scientific questions. You are comfortable operating in ambiguity while maintaining scientific rigor and clarity of thought.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Why Vivodyne?\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;High-Impact Mission\u0026lt;/strong\u0026gt; — Play a foundational role in transforming drug discovery through computational biology applied to the richest human tissue datasets in existence.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Method, Not Just Application\u0026lt;/strong\u0026gt; — You won\u0026#39;t just run pipelines. You\u0026#39;ll decide what pipelines should exist, whether they\u0026#39;re working, and what should replace them.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Multi-Disciplinary Exposure\u0026lt;/strong\u0026gt; — Work alongside experts in robotics, AI, tissue engineering, and microfluidics in a deeply cross-functional setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Growth Opportunities\u0026lt;/strong\u0026gt; — A fast-growing startup with significant autonomy, ownership, and direct influence over the biological data infrastructure and analytical strategy.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$115,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$160,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4017629007,"name":"Biology \u0026 Bioengineering","child_ids":[],"parent_id":4036086007}],"offices":[{"id":4044173007,"name":"San Francisco (Brisbane)","location":"San Francisco, California, United States","child_ids":[],"parent_id":null}]}],"meta":{"total":6}}