{"jobs":[{"absolute_url":"https://job-boards.greenhouse.io/primemedicine/jobs/6018864004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5164711004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6018864004,"updated_at":"2026-06-11T15:09:08-04:00","requisition_id":"632","title":"Accounting Operations Associate","company_name":"Prime Medicine","first_published":"2026-06-11T15:09:08-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Company Overview:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. \u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology \u0026amp;amp; oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit \u0026lt;a href=\u0026quot;http://www.primemedicine.com/\u0026quot;\u0026gt;www.primemedicine.com\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;u\u0026gt;Position Summary\u0026lt;/u\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Reporting to the Associate Director, Procurement, the Accounting Operations Associate will be responsible for managing the day-to-day procurement and accounts payable activities and providing general end user support across all Procure-to-Pay (P2P) functions\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;u\u0026gt;Key Responsibilities\u0026lt;/u\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Provide internal customer service support for the P2P processes and day-to-day activities, ensuring users are properly trained and transactions are recorded accurately.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain Vendor Master File and act as the primary contact for vendor inquiries regarding payment status and statement reconciliation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manage Accounts Payable mailbox to triage incoming mail appropriately and address external \u0026amp;amp; internal inquiries as needed.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead efforts around accounts payable efficiencies, including driving automation through AI adoption and other process enhancements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate \u0026amp;amp; execute the preparation of weekly payment run, working with accounting team to troubleshoot \u0026amp;amp; resolve any issues.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee and manage Concur for employee expense reports from review to reimbursement, ensuring compliance with company policies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support quarterly and annual financial audit processes by preparing the requested support and documentation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assist with special projects and ad-hoc analysis across accounting functions as assigned.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;u\u0026gt;Required Skills \u0026amp;amp; Competencies\u0026lt;/u\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree in finance or accounting, with 1-3 years of Procurement or Accounting experience (preferred).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in MS Office (especially Excel) and experience with accounting/ERP software\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated analytical skills to solve complex problems and address a variety of variables in situations with limited standardization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong organizational skills to effectively balance priorities, handle workload, and complete projects on time.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Organized and diligent, with time management abilities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong interpersonal skills for effectively communicating with internal \u0026amp;amp; external stakeholders of all levels.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to work independently across multiple financial systems and troubleshoot/resolve issues as needed.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Self-motivated and capable of working independently.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hybrid work position with some in-person attendance required (Cambridge, MA).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;U.S. Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$77,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$94,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4067707004,"name":"Finance","child_ids":[],"parent_id":4002430004}],"offices":[{"id":4001378004,"name":"Cambridge","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/primemedicine/jobs/5974789004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":5144432004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5974789004,"updated_at":"2026-06-10T08:32:08-04:00","requisition_id":"627","title":"Informatics Engineer","company_name":"Prime Medicine","first_published":"2026-04-19T14:24:36-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Company Overview:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. \u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology \u0026amp;amp; oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit \u0026lt;a href=\u0026quot;http://www.primemedicine.com/\u0026quot;\u0026gt;www.primemedicine.com\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;About the role\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We\u0026#39;re hiring an Informatics Engineer to build the scientific data and computing platform that powers Prime Medicine\u0026#39;s gene editing programs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will work in close partnership with our computational biology team and our cloud infrastructure team. The role suits someone who\u0026#39;s comfortable owning a platform end-to-end, building the engineering foundations that scientists across the organization rely on, including data pipelines and APIs through to AI-enabled internal tooling. Your engineering judgment about what to build and how to build it will shape how Prime Medicine works with scientific data day-to-day.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;What you\u0026#39;ll do\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and build the data platform connecting NGS instruments, laboratory informatics systems (Benchling), and AWS cloud compute; covering automated ingestion, provenance tracking, scalable storage, and observability.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build production-grade APIs, SDKs, and internal tools that bring genomic data and analytical capabilities to scientists across the organization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build the orchestration layer for the automated, event-triggered execution of our scientific pipelines. The pipelines themselves (amplicon-seq, off-target analysis, and others) are co-developed with our computational biology team; you\u0026#39;ll own how they run, scale, and integrate.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ship AI-powered and agentic capabilities such as RAG over internal scientific data, agentic workflows with human-in-the-loop review, and internal copilots that streamline routine workflows across the organization connecting both science and business needs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build integrations across the scientific tool chain so data moves reliably between ELNs, LIMS, instrument software, and cloud compute.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Translate scientific requirements into reliable, maintainable software, helping bring research prototypes into production-grade systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with computational biologists, lab scientists, and our cloud-support team to continuously improve platform performance, cost, and reliability.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;What we\u0026#39;re looking for\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is an Infrastructure engineering focused role, well suited to candidates whose primary background is software engineering, data engineering, or scientific platform engineering, with a strong interest in applying those skills to scientific problems.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Requirements\u0026lt;/strong\u0026gt;:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;5+ years of full-time engineering experience\u0026lt;/strong\u0026gt; (3+ for those with an MS or PhD) in production environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong Python programming skills.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Production AWS experience with depth in event-driven, cloud-native architectures\u0026lt;/strong\u0026gt;, including AWS Lambda, EventBridge (or comparable event-routing infrastructure), and Infrastructure as Code with Terraform or CDK.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Docker / containerization\u0026lt;/strong\u0026gt;, Git-based workflows, CI/CD, code review, and testing code in DEV/TEST environments before deploying to production.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;A track record of building integrations and automations.\u0026lt;/strong\u0026gt; \u0026lt;strong\u0026gt;Experience in a life-science related industry involving scientific or regulated data, such as biotech, pharma, healthtech, clinical informatics, scientific instrumentation, or agricultural genomics. \u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Nice to have\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;NGS expertise.\u0026lt;/strong\u0026gt; Knowledge of NGS technology, workflows and pipeline architecture is strongly preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Hands-on workflow orchestration experience.\u0026lt;/strong\u0026gt; Familiarity with Nextflow/NextFlow Tower/Seqera Platform preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Laboratory informatics experience\u0026lt;/strong\u0026gt; with Benchling or comparable ELN/LIMS, as an operator, builder, or administrator.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;AI / LLM tooling and agentic systems\u0026lt;/strong\u0026gt; (LangChain, LangGraph, MCPs, RAG architectures).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Gene editing familiarity:\u0026lt;/strong\u0026gt; CRISPR, base editing, prime editing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;GxP / 21 CFR Part 11 / regulated-software experience.\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Plotly Dash, Streamlit, Spotfire, Retool, \u0026lt;/strong\u0026gt;or similar tools for internal apps and data visualizations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience managing or querying relational databases (PostgreSQL, MSSQL).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Interview process\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The process includes a recruiter conversation, a hiring manager interview, and a small panel that includes computational biology, engineering, and wet lab partners. A Python coding exercise is part of the process\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Logistics and policy\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Hybrid with office in Cambridge, MA.\u0026lt;/strong\u0026gt; \u0026lt;strong\u0026gt;We are not currently able to sponsor visas.\u0026lt;/strong\u0026gt; US work authorization at the time of application is required.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Competitive base salary, equity, and standard benefits.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;U.S. Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$134,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$163,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4072619004,"name":"Informatics","child_ids":[],"parent_id":4002514004}],"offices":[{"id":4001378004,"name":"Cambridge","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/primemedicine/jobs/5812799004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5056492004,"location":{"name":"Watertown, MA"},"metadata":null,"id":5812799004,"updated_at":"2026-04-30T09:54:14-04:00","requisition_id":"601","title":"Senior Laboratory Operations Associate ","company_name":"Prime Medicine","first_published":"2026-02-25T11:45:12-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Company Overview:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. \u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology \u0026amp;amp; oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit \u0026lt;a href=\u0026quot;http://www.primemedicine.com/\u0026quot;\u0026gt;www.primemedicine.com\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;div\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;u data-olk-copy-source=\u0026quot;MailCompose\u0026quot;\u0026gt;Position Summary\u0026lt;/u\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;We are seeking a highly motivated Senior Laboratory Operations Associate with 3–5 years of hands-on experience supporting high-throughput, high-hazard chemistry, vivarium, and GMP operations. This individual will play a critical role in ensuring the smooth operation of a dynamic laboratory environment. The ideal candidate has a deep understanding of management of high-volume high hazard chemicals, asset management, is adaptable, detail-oriented, and a strong cross-functional communicator with a passion for operational excellence.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026amp;nbsp;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026lt;strong\u0026gt;K\u0026lt;u\u0026gt;ey Responsibilities\u0026lt;/u\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Under the guidance of the Senior Laboratory Manager, manage day-to-day operations in high-volume chemistry, biology, animal, and GMP laboratories, including supply management, asset management, chemical inventory, and waste handling.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Oversee management and administration of laboratory instrument service agreements, remedial repair, scheduling preventative maintenance, and digital asset management system.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Manage relationship with select vendors and suppliers.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Oversee the receipt, organization, and distribution of reagents and consumables to support chemistry workflows including 55-gallon drums of virgin chemicals and waste.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Ensure appropriate segregation, labeling, storage, and disposal of high-hazard chemicals, including Class A, Class B, water reactive materials, organic acids, inorganic acids, bases, and acutely toxic chemicals.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Coordinate with chemists to prepare and dispose of solid-phase resins, solvents, and purification materials in compliance with EHS protocols.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Monitor and maintain process systems and chemicals in 780 CMR/International Building Code (IBC) §307 designated High-Hazard Group Occupancy (H3 room).\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Collaborate with vivarium staff to support animal research workflows, including supply delivery, sanitization cycles, live animal deliveries, and carcass disposal in accordance with 105 CMR 480.000.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Support cross-functional workflows between R\u0026amp;amp;D and GMP labs.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Ensure documentation, materials movement, and environmental monitoring align with GMP compliance expectations.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Other responsibilities as required.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026amp;nbsp;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;u\u0026gt;Qualifications\u0026lt;/u\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026lt;strong\u0026gt;Education \u0026amp;amp; Experience\u0026lt;/strong\u0026gt;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· 3–5 years of direct hands-on experience in laboratory operations within a biotechnology environment.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Experience supporting high-hazard chemistry, vivarium operations, GMP manufacturing, and BSL-2 biology labs.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026amp;nbsp;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026lt;strong\u0026gt;Required Skills \u0026amp;amp; Competencies\u0026lt;/strong\u0026gt;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Experience working in ISO 5, 7, and 8 cleanroom environments.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Experience with ‘just-in-time’ supply chain management, KANBAN, 5S/Lean.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Familiarity with lab and facility management systems (e.g., LIMS, CMMS, asset management).\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Comfortable working in environments requiring strict compliance: H3 occupancy, BSL-2, vivarium, and GMP.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Strong organizational and multitasking skills with an ability to work independently.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Excellent communication skills, both verbal and written.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Familiarity with 527 CMR 1.00, RCRA, EPA, DOT, HAZWOPPER, and IATA regulations.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026amp;nbsp;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;\u0026lt;strong\u0026gt;Physical Requirements\u0026lt;/strong\u0026gt;\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Ability to be on-call to receive and respond to alarms within 1 hour.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Ability to lift 50lbs, stand for extended periods, and perform repetitive physical tasks.\u0026lt;/div\u0026gt;\n\u0026lt;div\u0026gt;· Comfortable working with hazardous materials while wearing appropriate PPE including the Advantage 420 Respirator, Tyvek Full GMP Sterile Coverall, lab coat, and ‘silvershield’ gloves.\u0026lt;/div\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;U.S. Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$82,010\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$113,300 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4067671004,"name":"Lab Management","child_ids":[],"parent_id":4002514004}],"offices":[{"id":4033789004,"name":"Arsenal St","location":"Watertown, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/primemedicine/jobs/5839127004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5069479004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5839127004,"updated_at":"2026-04-30T09:54:14-04:00","requisition_id":"619","title":"Senior Scientist, Drug Metabolism \u0026 Pharmacokinetics (DMPK)","company_name":"Prime Medicine","first_published":"2026-03-27T07:42:26-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Company Overview:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. \u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology \u0026amp;amp; oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit \u0026lt;a href=\u0026quot;http://www.primemedicine.com/\u0026quot;\u0026gt;www.primemedicine.com\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h1\u0026gt;Position Overview\u0026lt;/h1\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a motivated and skilled Senior Scientist to join the Nonclinical Development group, contributing to the DMPK function in support of exploratory and IND-enabling programs across Prime Medicine’s pipeline. Reporting to the Associate Director, DMPK/Bioanalytical Sciences, this individual will independently analyze and interpret datasets from \u0026lt;em\u0026gt;in vivo \u0026lt;/em\u0026gt;studies, contribute to nonclinical regulatory documents, and work cross-functionally with pharmacology, translational biology and external CROs, to ensure high-quality DMPK data packages are delivered to support program timelines. The ideal candidate has a strong foundation in \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt; pharmacokinetics for RNA therapeutics and/or LNP-based delivery systems, thrives in a fast-paced and matrixed organization, and possesses the flexibility and positive attitude needed to make meaningful contributions to the Nonclinical Development team.\u0026lt;/p\u0026gt;\n\u0026lt;h1\u0026gt;Primary Responsibilities\u0026lt;/h1\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Analyze and interpret PK study data from exploratory and IND-enabling \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Perform non-compartmental analysis (NCA) using Phoenix WinNonlin to derive key PK parameters (Cmax, AUC, T½, Vd, CL).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leverage expertise in DMPK to provide recommendations for \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt; study designs in collaboration with pharmacology and key stakeholders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Perform bioanalytical assay development (30%) and collaborate with bioanalytical scientists to trouble-shoot challenges during method development to ensure quantitative methods for key analytes (LNP lipid components, mRNA, pegRNA, PD biomarkers) meet regulatory expectations and data quality standards..\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to nonclinical regulatory documents including pharmacokinetics summaries and nonclinical study reports under the guidance of senior stakeholders in Nonclinical Development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain thorough records in the electronic laboratory notebook (ELN); prepare clear data summaries, presentations, and technical memos for program team and governance meetings.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h1\u0026gt;Qualifications\u0026lt;/h1\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Minimum Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;D. in pharmacokinetics, pharmaceutical sciences, pharmacology, biochemistry, or a related discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;6+ years of cumulative experience. Industry experience (biotech or pharmaceutical) with direct responsibility for \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt; DMPK study design, execution, and interpretation is required; postdoctoral training in a DMPK or translational pharmacology setting is strongly preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience with \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt; PK studies in preclinical models and proficiency in NCA using Phoenix WinNonlin or equivalent software.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with regulatory expectations for nonclinical DMPK assessments and bioanalytical assay development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to coordinate with external CROs, including scientific guidance, protocol development, and data review..\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong written and verbal communication skills; ability to present complex DMPK data clearly to multidisciplinary audiences.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Highly self-motivated, collaborative, and organized, with the ability to manage multiple priorities independently in a fast-paced matrix environment.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Preferred Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with PK/PD modeling concepts; experience with Phoenix WinNonlin modeling modules a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with LNP-based delivery systems and/or RNA therapeutics (mRNA, siRNA, ASO, sgRNA or related modalities).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with exploratory DMPK studies, evaluating new delivery vehicles and evaluation of biodistribution using \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with bioanalytical platforms supporting DMPK studies, including LC-MS/MS, RT-qPCR/ddPCR, ELISA/MSD.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability and excitement to contribute to the development and success of the Nonclinical Development team.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;U.S. Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$145,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$177,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4045133004,"name":"Technical Development \u0026 Operations","child_ids":[4067662004,4067804004,4076520004,4076521004,4067663004,4076522004,4076523004,4067664004,4067665004,4067666004],"parent_id":null}],"offices":[{"id":4001378004,"name":"Cambridge","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/primemedicine/jobs/5839123004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5069476004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5839123004,"updated_at":"2026-04-30T09:54:14-04:00","requisition_id":"618","title":"Senior Scientist, Safety Assessment ","company_name":"Prime Medicine","first_published":"2026-03-27T07:34:40-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Company Overview:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. \u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology \u0026amp;amp; oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit \u0026lt;a href=\u0026quot;http://www.primemedicine.com/\u0026quot;\u0026gt;www.primemedicine.com\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Position Overview\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are seeking an enthusiastic, self-motivated Senior Scientist to join the Nonclinical Development group, supporting the nonclinical safety assessment function for IND-enabling programs across Prime Medicine’s pipeline. Reporting to the Associate Director, Safety Assessment, the successful candidate will support the design, execution, and interpretation of nonclinical safety studies conducted both in-house and at CROs, with an initial focus on liver-targeted therapeutics. This role requires hands-on involvement in assay execution and troubleshooting, as well as active participation in study oversight of work being done at CRO and data analysis.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role requires collaboration within cross-functional teams. The ideal candidate will hold a Ph.D. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. \u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Primary Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Contribute to nonclinical safety activities as part of cross-functional Discovery and Development project teams, supporting program progression through IND-enabling stages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design, execute, and troubleshoot nonclinical safety studies, including hands-on laboratory work (~30%) to support assay development, data generation, and issue resolution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support the execution and oversight of nonclinical safety studies (GLP and non-GLP) at CROs, including active involvement in troubleshooting assay and study-related challenges.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyze and interpret study data with guidance and contribute to the preparation of study reports and supporting documents for regulatory submissions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with Pharmacology, DMPK, and other functions to support exploratory studies (e.g., exploratory toxicology, DMPK, biodistribution, and delivery platform evaluation).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to evaluation of new delivery approaches, Lipid and RNA components, and emerging targets to support pipeline expansion.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assist in identifying potential safety findings and contribute to discussions on data interpretation and next steps.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure studies and internal activities are conducted in compliance with regulatory guidelines and internal standards.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Preferred Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. in toxicology or a related discipline with 6+ years of biopharmaceutical industry experience, or M.S. in toxicology or a related field with 10+ years of relevant biopharmaceutical industry experience supporting drug development in nonclinical safety/toxicology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in large molecule therapeutic development, along with a background in immunology, is desirable.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understanding of toxicology principles, nonclinical safety evaluation, and the drug development process, with some experience interpreting toxicology data and contributing to technical and scientific reports.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrates strong scientific judgment and leadership with the ability to evaluate information, identify potential issues, and propose practical solutions with guidance as needed.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Highly organized and detail-oriented with strong attention to accuracy and quality.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong communication and collaboration skills, with the ability to work effectively across multidisciplinary teams and with external partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience supporting nonclinical studies at CROs is preferred but not required.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;U.S. Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$145,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$177,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4045133004,"name":"Technical Development \u0026 Operations","child_ids":[4067662004,4067804004,4076520004,4076521004,4067663004,4076522004,4076523004,4067664004,4067665004,4067666004],"parent_id":null}],"offices":[{"id":4001378004,"name":"Cambridge","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/primemedicine/jobs/5969061004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5141738004,"location":{"name":"Watertown, MA"},"metadata":null,"id":5969061004,"updated_at":"2026-04-30T09:54:14-04:00","requisition_id":"625","title":"Sr. Clinical Research Coordinator, Clinical Operations","company_name":"Prime Medicine","first_published":"2026-04-13T16:15:08-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Company Overview:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. \u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology \u0026amp;amp; oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit \u0026lt;a href=\u0026quot;http://www.primemedicine.com/\u0026quot;\u0026gt;www.primemedicine.com\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Position Overview:\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Join a collaborative, agile and dynamic Clinical Development Operations (CDO) team by leading and contributing to transformative clinical programs for patients in rare diseases and beyond.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;In this position, you will be hands-on in day-to-day study execution, working closely with internal study team members, clinical sites, and external CROs and vendors. This position is ideal for someone who thrives in a fast-paced, evolving environment, is comfortable wearing multiple hats, and is eager to learn more about clinical trial management and execution. This is a hybrid role requiring a combination of in-office presence (Watertown, MA) and remote work, with expectations aligned to team and business needs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Key Responsibilities:\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Support the execution of clinical trials from startup through closeout, ensuring adherence to protocol, timelines, and quality standards\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Assist with site startup activities, including regulatory document collection, IRB/EC submissions, and site readiness/activation\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Support development of study and site-facing materials (e.g., ICFs, recruitment materials, study manuals, CCGs, study tools) and coordinate cross-functional review and approval\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Prepare and maintain meeting minutes, action items, and follow-ups for key study team meetings\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Maintain study documentation (e.g., sponsor TMF oversight and ISF support) to ensure completeness, quality, and inspection readiness\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Oversee CRO/vendor TMF activities, ensuring alignment with sponsor expectations, TMF plans, and filing timelines\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Track study progress, enrollment, IRB/EC submissions and queries, and key operational metrics; proactively identify and escalate risks to timelines or deliverables\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Serve as a primary point of contact for CRAs and sites to address day-to-day operational questions and issues\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Track and monitor key subject visits and study milestones to ensure protocol compliance and data integrity\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Support inspection readiness activities, including TMF reviews, audit support, and resolution of findings\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Support clinical sample management activities, including coordination of central labs, sample logistics, tracking, and issue resolution\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Review clinical data, monitoring reports, and protocol deviations to ensure quality, compliance, and timely issue resolution\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Contribute to SOP development, process improvements, and operational best practices within a growing organization\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Qualifications:\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· BS/BA/RN Degree in science or a health-related field is preferred\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Minimum 2–4 years of clinical research experience; sponsor experience is strongly preferred.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Familiarity with clinical trial operations, ICH-GCP, and regulatory requirements\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Experience and understanding of EDC systems, TMF systems, and clinical trial documentation\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Familiarity with clinical data review and data management processes, including Data Monitoring Committees\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Highly organized with strong attention to detail\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Ability to manage multiple priorities with a sense of urgency in a fast-paced environment\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Strong communication and relationship-building skills\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Resourceful, proactive problem-solver with a “do-what-it-takes” mindset\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Comfortable operating in a dynamic environment with evolving processes and priorities\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Self-motivated, collaborative, and able to work both independently and cross-functionally\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Positive, team-oriented attitude with a passion for advancing innovative therapies for patients\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;· Excitement to contribute to Prime Medicine’s culture!\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability, protected veteran status, or any other characteristic protected by law.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;U.S. Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$94,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$114,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4067721004,"name":"Clinical","child_ids":[],"parent_id":4066936004}],"offices":[{"id":4001378004,"name":"Cambridge","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]}],"meta":{"total":6}}