{"jobs":[{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6144041004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5200376004,"location":{"name":"London"},"metadata":null,"id":6144041004,"updated_at":"2026-08-25T08:49:11-04:00","requisition_id":"468","title":"Application Support Engineer (Third Party Systems), London","company_name":"Isomorphic Labs","first_published":"2026-08-14T04:57:51-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a talented Integration Engineer to own, secure, and scale our suite of internal, multi-user tools and applications.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will be responsible for a number of vendor applications that we deploy in our own environments. You will bridge the gap between Integration, Operations, and Security. You will be responsible for the full software lifecycle; from configuring secure cloud environments, orchestrating application deployments, running automated security scanning, and executing continuous updates with minimal downtime.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Platform Deployment \u0026amp;amp; Lifecycle Management:\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Deploy, upgrade, patch, and maintain multi-user self-hosted software instances across cloud environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Plan and execute seamless, low-downtime application maintenance and database migration windows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate with customer identity platforms to provide secure access.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Configure monitoring and alerting, with runbooks for application health management\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Continuous Deployment \u0026amp;amp; Orchestration:\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Build and maintain continuous deployment pipelines to automate application delivery (primarily for Kubernetes).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain Infrastructure-as-Code (IaC) templates and configuration management scripts for reliable instance provisioning.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Application Security \u0026amp;amp; Vulnerability Scanning:\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Integrate continuous security scanning into pipelines to inspect application code, dependencies, and container images for vulnerabilities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Remediate identified CVEs and enforce compliance and security standards across all internal platform tooling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identity \u0026amp;amp; Access Integration: Configure Single Sign-On (SSO), Role-Based Access Control (RBAC), and directory integration (SAML 2.0 / OIDC) for onboarded applications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Endpoint \u0026amp;amp; Cloud Deployment: Automate and manage software rollouts across desktop fleets, headless Linux machines, and cloud environments using modern deployment pipelines and configuration tools.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Configuration \u0026amp;amp; Hardening: Enforce security baseline configurations, secrets management, and access controls for all newly introduced software packages.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Hands-on Kubernetes \u0026amp;amp; Containerization:\u0026lt;/strong\u0026gt; Experience deploying, managing, and scaling multi-user applications on Kubernetes\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;CI/CD \u0026amp;amp; Automation:\u0026lt;/strong\u0026gt; Proven track record building continuous deployment pipelines using tools such as GitHub Actions, GitLab CI, ArgoCD, or Jenkins.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Security Scanning \u0026amp;amp; Vulnerability Management:\u0026lt;/strong\u0026gt; Experience implementing and analyzing container and dependency security scanning tools\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Infrastructure as Code (IaC):\u0026lt;/strong\u0026gt; Proficiency with Terraform, OpenTofu, or similar for provisioning repeatable environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Identity \u0026amp;amp; Access Management (SSO):\u0026lt;/strong\u0026gt; Practical experience configuring Single Sign-On (SSO) and Directory integration via SAML 2.0 / OIDC (e.g., Okta, Azure AD/Entra ID).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Scripting Skills:\u0026lt;/strong\u0026gt; Proficiency in Python, Bash, or Go to automate maintenance routines and internal workflow.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;GitOps Methodology:\u0026lt;/strong\u0026gt; Hands-on experience with GitOps tools like ArgoCD or Flux for declarative state enforcement.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Database \u0026amp;amp; Storage Administration:\u0026lt;/strong\u0026gt; Experience backing up, restoring, and tuning databases commonly used by self-hosted applications (PostgreSQL, MySQL, Redis).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Observability Stacks:\u0026lt;/strong\u0026gt; Experience using monitoring, alerting, and logging tools\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044354004,"name":"Tech","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6209670004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5223374004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6209670004,"updated_at":"2026-09-28T11:10:46-04:00","requisition_id":"493","title":"Associate Director, Clinical Supply Chain, Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-09-28T11:10:46-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a proactive, self-driven, highly organized, and entrepreneurial Clinical Supply Chain colleague to lead end-to-end clinical trial material (CTM) planning, vendor management, packaging, labeling, inventory management, and global distribution operations. Reporting directly to the Head of Early Development, you will serve as the clinical supply authority within a lean Pharmaceutical Sciences \u0026amp;amp; CMC Manufacturing team, acting as a direct partner to Clinical Operations and the larger Clinical Development organization. As part of an AI-first company, you will help us reimagine how we bring new medicines to patients.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role is designed for growth. As our pipeline advances, you will be the foundational architect of our clinical supply operations - scaling systems, processes, and vendor networks to support future clinical studies in different modalities and therapeutics areas.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Operating within an agile model, you will execute operations through external clinical packaging and labeling vendors, central/regional depots, specialized temperature-controlled chain couriers, and Interactive Response Technology (IRT/RTSM) providers. Internally, you will bridge between drug manufacturing with Clinical Operations for clinical trial execution.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Clinical Supply Planning \u0026amp;amp; Execution\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Dynamic Demand Forecasting: Build and maintain flexible clinical supply models tailored to the unpredictable pace of clinical trials, ensuring uninterrupted patient dosing while minimizing drug waste.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Rapid-Response Resupply: Manage flexible investigational product fulfillment and site replenishment strategies to support dynamic protocol milestones, dose adjustments, and study demand fluctuations across participating trial sites.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Pharmacy Manuals \u0026amp;amp; Site Support: Collaborate with internal colleagues and Clinical CROs to author and review the Investigational Product (IP) Handling and Pharmacy Manuals, establishing clear site-level guidance for drug storage, handling, accountability, and dose preparation, reconciliation, and destruction.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Packaging, Labeling \u0026amp;amp; Distribution Logistics\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Packaging \u0026amp;amp; Label Design: Direct secondary packaging, blinding/kitting strategies, and label generation for clinical trial supplies, ensuring regulatory compliance with applicable regional and global standards and regulations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Depot \u0026amp;amp; Logistics Management: Select and manage central and regional clinical depots; oversee qualified domestic shipping lines, secure chain-of-custody protocols, and specialty courier operations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understand the latest retest/expiry dating for clinical supplies by coordinating with Analytical Development to get the latest shelf life on clinical supplies to ensure recovery/recalls can be done without interrupting or delaying the clinical study.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Temperature Monitoring \u0026amp;amp; Excursions (TEs): Implement continuous temperature monitoring solutions across shipments and depot storage.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Triage temperature excursions in real time, partnering with Analytical Chemistry and Quality Assurance to assess stability impact and execute rapid product disposition.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Accountability, Reconciliation \u0026amp;amp; Destruction: Direct end-of-study IP reconciliation, returns, and authorized destruction workflows across trial sites and depots in compliance with cGMP/GCP and ICH standards.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Direct qualified domestic and international shipping vendors and distribution strategies , QP release coordination , import/export permits/license requirements, depot networks and VAT planning and recovery.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Clinical CRO, IRT/RTSM \u0026amp;amp; Clinical Operations Partnership\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Clinical CRO Alignment: Serve as the primary clinical supply chain liaison to Clinical CROs, synchronizing supply readiness with clinical timelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;IRT/RTSM System Implementation: Partner with Clinical Operations and IRT providers to design system functional specifications, supply buffer strategies, reorder triggers, predictive resupply logic, and User Acceptance Testing (UAT).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Site Activation Readiness: Track country- and site-level regulatory approvals, import/export requirements, and depot release gates to ensure Investigational Product arrives on-site well in advance of First Patient In (FPI).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Supply Chain Scalability\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Small Molecule Scaling: Structure the transition from early, open-label studies to larger, multi-center, randomized, double-blind, placebo/comparator-controlled trials, including managing matching placebo/comparator supplies and complex blinded packaging.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Supply Systems Evolution: Drive the selection and implementation of supply chain enterprise software, inventory tracking systems, and digital dashboards as company development activities scale.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Quality, Compliance \u0026amp;amp; Vendor Governance\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Vendor Management: Direct technical RFPs, contract negotiations, Statements of Work (SOWs), and performance metrics (KPIs/SLAs) for clinical packaging/labeling CMOs/CPOs (Contract Manufacturing/Packaging Organizations), logistics providers, and storage depots.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Batch Release \u0026amp;amp; Import/Export Documentation: Review and approve packaging/labeling batch records, release documentation, material shipping authorizations, and domestic transport permits in partnership with QA.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;GxP Compliance \u0026amp;amp; Audit Readiness: Ensure all clinical supply activities comply strictly with cGMPs, ICH, GDPs and CGPs and internal quality management systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Direct technical RFIs, RFPs, SOWs, and KPIs, while tracking trial supply spend and vendor invoice approvals.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Education: Bachelor’s or Master’s degree in Supply Chain Management, Logistics, Life Sciences, Chemical/Industrial Engineering, Pharmacy, or a related discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Industry Experience: 7+ years of direct experience in clinical supply chain management, clinical logistics, or investigational material management within a pharmaceutical or biotechnology company.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Study Start-up Experience: Proven experience supporting clinical trials, with a firm grasp of logistics, rapid-response replenishment, and flexible kit demand.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Packaging \u0026amp;amp; Distribution: Practical experience managing secondary packaging, clinical labeling,depot operations, and temperature-controlled transportation planning/execution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;GxP \u0026amp;amp; Regulatory Rigor: Thorough working knowledge of cGMP, cGCP, Good Distribution Practices (GDP); global clinical supply regulations and experience working with Regulatory and Legal functions in these areas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exceptional communication, negotiation, and cross-functional leadership skills, with a proven ability to coordinate complex operational timelines across diverse technical and clinical stakeholders.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Preferred:\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Prior experience in a high-growth, venture-backed startup or lean biotech environment where autonomy, technical versatility, and building processes from the ground up are required.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Biologics Supply Chain Experience: Direct experience managing clinical supply logistics for biologic modalities and ancillary parenteral administration supplies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Blinded Trial Experience: Experience managing supplies for randomized, double-blind, placebo/comparator-controlled clinical trials, including blinding maintenance and placebo matching.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with Section 3.2.P (Drug Product / Container Closure) labeling sections or pharmacy-related components of regulatory filings (IND/IMPD).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4124682004,"name":"Clinical ","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6146410004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5201688004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6146410004,"updated_at":"2026-10-09T16:39:32-04:00","requisition_id":"469","title":"Associate Director, Translational Medicine, Oncology, Cambridge, MA ","company_name":"Isomorphic Labs","first_published":"2026-08-19T08:43:32-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;The experienced Associate Director of Translational Medicine will lead, own and execute the Translational Medicine strategy for Isomorphic’s oncology portfolio. Reporting to the Head of Translational Medicine, this is an opportunity for an innovative leader to play a foundational role in shaping and advancing oncology programs through clinical proof of concept. They will leverage AI and emerging technologies to ensure efficient outcomes with a high probability of success.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead and execute the Translational Medicine strategy\u0026lt;strong\u0026gt; \u0026lt;/strong\u0026gt;across oncology programs. Ensure readiness of clinical biomarker assays and delivery of corresponding data to address mechanism of action, predictive and prognostic insights, mechanisms of drug resistance and to inform future indications and combinations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as a core member of the oncology program teams and subject matter expert for cancer biology. Collaborate with cross-functional teams to set the program strategy and clinical trial design across tumor types and drug modalities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deliver clinically validated assays and advance companion diagnostic development for biomarker selected studies.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work closely with the early portfolio scientific teams to ensure clinical input is incorporated at the start of the drug development process, and preclinical insights are translated into the clinical design\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with AI and Computational Biology teams to identify, create and utilize innovative tools for analysis of biomarker and translational datasets, accelerate diagnostic advances and explore new approach methodologies (NAMs).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as a key contributor to the translational sections of clinical and regulatory documents including INDs, IBs, clinical protocols, lab manuals, and briefing books.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate across internal and external stakeholders to represent and communicate the translational strategy.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee and manage external CROs to ensure on time and robust data delivery\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. or similar in biology or related field\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;7+ years of translational experience within biotech or pharma including oncology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven success implementing and executing translational strategy, clinical biomarkers and diagnostic development in oncology studies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working cross-functionally with key stakeholders internally as well as external vendors and collaborators.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Significant expertise in cancer biology and drug development\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong appetite to work in an AI-first environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Willingness to go beyond traditional assays and approaches, incorporating cutting edge methodologies that may enhance therapeutic probability of success and velocity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Sense of urgency and accountability to operate in a fast-paced environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Flexibility to adapt to changing timelines and priorities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong leadership and excellent communication skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience working on global oncology studies across multiple clinical phases, tumor types and drug modalities (small molecules, biologics, peptides, glues)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Companion diagnostic experience across countries and through regulatory approval\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to conduct analysis across multi-omic datasets independently and in collaboration with biometrics\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience utilizing AI to enhance translational work\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4124682004,"name":"Clinical ","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6209688004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5223382004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6209688004,"updated_at":"2026-09-29T09:08:29-04:00","requisition_id":"494","title":"Candidate Experience Coordinator, Cambridge, MA ","company_name":"Isomorphic Labs","first_published":"2026-09-29T09:08:29-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As a Candidate Experience Coordinator, you are the engine of our Talent Acquisition (TA) function. You won’t just support recruitment; you will architect, own, and lead the candidate journey through interdisciplinary collaboration.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Overseeing complex global scheduling, you will own the holistic end-to-end candidate experience— running an efficient and exceptional interview process from the first touchpoint to the final stages. You will drive data integrity to influence hiring decisions, whilst also serving as a process engineer who identifies bottlenecks and implements smoother workflows. This position is designed as a launchpad for your career, giving you interdisciplinary visibility and significant project ownership across the talent acquisition lifecycle.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;1. Own the Candidate Experience Architecture\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Curate the Journey:\u0026lt;/strong\u0026gt; Act as a primary, consistent point of contact for candidates, ensuring every interaction is timely, seamless, and supportive. You will seamlessly balance high volume scheduling with candidate care.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Host the Onsite Experience:\u0026lt;/strong\u0026gt; Act as the host and central lead for our onsite (or virtual) interview days, ensuring candidates feel welcomed, prepared, and impressed.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Humanise Communication:\u0026lt;/strong\u0026gt; Partner across the team to design candidate communications. You will ensure our templates are authentic and aligned with our values, including managing early-stage rejections with empathy and professionalism.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Scheduling Excellence:\u0026lt;/strong\u0026gt; Orchestrate complex, interdisciplinary interview loops across multiple time zones with speed and efficiency, proactively managing any last-minute changes with candidates, interviewers, and hiring managers.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;2. Drive Operational Excellence \u0026amp;amp; Data Integrity\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Be a \u0026quot;Data Guardian”:\u0026lt;/strong\u0026gt; Champion the quality and consistency of our data within our ATS (Greenhouse). You will manage job set up, build interview processes and ensure\u0026amp;nbsp; candidate statuses are meticulously maintained to enable accurate reporting.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Onboarding Operations: Oversee critical onboarding and compliance operations, such as right-to-work checks, pobu (integrating people data with relevant google systems), and background checks. Upskill and educate the talent team on criticality of accurate data and Greenhouse (ATS) best practices in both hiring and onboarding processes.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Feedback Loops:\u0026lt;/strong\u0026gt; Partner with the Principal Talent Lead to analyse candidate survey data. You will turn these insights into meaningful actions, blending data-driven and experiential perspectives to continuously elevate our standards.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Identify \u0026amp;amp; Eradicate Bottlenecks:\u0026lt;/strong\u0026gt; Proactively flag recurring scheduling challenges or process delays. You won’t just follow the process; you will help evolve it by suggesting improvements and piloting new workflows.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;3. Enablement \u0026amp;amp; Strategic Partnership\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Scaling processes:\u0026lt;/strong\u0026gt; Utilising AI, you will assist in documenting core processes for TA, creating clear and consistent guides for everything from complex scheduling to offer approval workflows. Additionally, you will ensure effective training for any new coordinators and wider TA members.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Champion Interdisciplinary Partnership:\u0026lt;/strong\u0026gt; You will have opportunities for domain alignment with specific verticals, allowing you to build deeper context on the roles you support and partner closely with Hiring Managers, thereby leveraging diverse skills and perspectives across the business.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Exceptional Organisation:\u0026lt;/strong\u0026gt; Ability to prioritise multiple functions and tasks while maintaining the highest attention to detail in a fast-paced environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Experience Centric:\u0026lt;/strong\u0026gt; A strong focus on providing the best possible candidate experience, with the empathy to manage relationships through the entire recruitment lifecycle.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Tech \u0026amp;amp; Data Savvy:\u0026lt;/strong\u0026gt; Experience using online calendar/meeting applications (G-Suite preferred) and a data-driven approach with a strong desire to advocate for clean data.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Communication:\u0026lt;/strong\u0026gt; Excellent communication skills, capable of keeping stakeholders updated and writing \u0026quot;human-first\u0026quot; correspondence.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Global Mindset:\u0026lt;/strong\u0026gt; Experience scheduling and complex coordination across multiple time zones.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Process Mindset:\u0026lt;/strong\u0026gt; The ability to learn complex systems quickly and a willingness to question \u0026quot;how things are done\u0026quot; to find better solutions.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;ATS Expertise:\u0026lt;/strong\u0026gt; Deep experience with Applicant Tracking Systems, specifically \u0026lt;strong\u0026gt;Greenhouse\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Project Management:\u0026lt;/strong\u0026gt; Experience leading or contributing to operational projects (e.g., event logistics, data cleanup, survey rollouts).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Agency or Search Firm Experience:\u0026lt;/strong\u0026gt; Experience acting as the main point of contact for external partners.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044361004,"name":"Central  ","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6143052004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5199765004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6143052004,"updated_at":"2026-08-19T08:43:47-04:00","requisition_id":"467","title":"Clinical Contracts Manager, Cambridge, MA ","company_name":"Isomorphic Labs","first_published":"2026-08-19T08:43:47-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;The Clinical Contracts Manager acts as the primary point of contact for all vendor outsourcing and business contracting initiatives within their assigned therapeutic and functional areas. Operating at an organizational level, this role drives vendor selection, supports negotiation of Master Service Agreements (MSAs) and Clinical Trial Agreements (CTAs), and manages vendor related study budgets and contract lifecycle activities. The Clinical Contracts Manager collaborates closely with Clinical Operations, Data Management, Clinical Sciences, Clinical Systems, Biosample Operations, Finance, Legal, and other cross-functional stakeholders to ensure predictable trial execution, financial alignment, and compliance with GCP and FDA regulatory standards.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Vendor Management \u0026amp;amp; Contracting\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Provide primary outsourcing and vendor management support for clinical development functional areas across the portfolio.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Independently lead RFI and RFP processes, analyze supplier services, proposals, and budgets, conduct bid defense meetings, and recommend vendor selection for executive decision-making.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Negotiate and execute complex vendor agreements and Master Service Agreements (MSAs) with preferential terms and pricing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define and implement vendor assessment criteria, benchmark metrics, and process improvement initiatives to optimize clinical outsourcing.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Clinical Trial Execution \u0026amp;amp; Site Support\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Drive negotiations for Clinical Trial Agreements (CTAs) and investigator budgets directly with clinical sites.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner closely with Clinical Trial Managers, program teams, and CROs to ensure vendors deliver against study timelines, quality standards, and budget expectations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assess and integrate potential AI tools to facilitate and enable contract negotiations and management.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure full consistency between contractual agreements and operational trial implementation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Monitor study progress, vendor deliverables, and resource allocation throughout the study lifecycle, supporting teams in final financial reconciliation at study closeout.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Risk Management, Compliance \u0026amp;amp; Governance\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Actively monitor study progress for scope changes, driving negotiations for change orders and associated costs to minimize sponsor risk.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify contractual risks, mitigate scope creep, and ensure strict adherence to Fair Market Value (FMV) standards, legal requirements, and healthcare compliance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proactively address contractual challenges, develop risk mitigation plans, and facilitate escalation management for leadership review when needed.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Participate in vendor oversight and governance meetings, supporting study teams in resolving vendor performance issues.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Seek out, assess and potentially assist in onboarding potential AI solutions within this space that would prove helpful to the organization\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree (BA/BS); degree in Healthcare, Science or Finance preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Minimum 5+ years of experience in clinical outsourcing, contracting, procurement, or finance within a pharmaceutical, biopharma, CRO, or clinical research setting.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;In-depth knowledge of clinical trial execution, CRO outsourcing models, and regulatory guidelines (GCP/FDA).\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oncology and/or Rare Disease experience required.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to confidently and independently complete and/or drive all key responsibilities listed above.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong contract negotiation, budget management, and project management skills with a proven track record across multi-project timelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exceptional written and oral communication skills, with the ability to convey engagement objectives and maintain effective dialogue with internal and external partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrates an AI-curious mindset, with an interest in exploring and leveraging emerging AI technologies to streamline contract lifecycle management and enhance operational efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strategic and analytical thinker with excellent problem-solving capabilities and adaptability in fast-paced, matrixed environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to build strong cross-functional relationships, mentor team members, and drive efficient business solutions across functional and regional boundaries.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4124682004,"name":"Clinical ","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/4336321004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4215639004,"location":{"name":"London"},"metadata":null,"id":4336321004,"updated_at":"2026-07-17T05:51:39-04:00","requisition_id":"2","title":"General Application - Register Your Interest","company_name":"Isomorphic Labs","first_published":"2022-02-08T04:44:19-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;We are currently accepting expressions of interest from experienced:\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Software Engineers\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;ML Research Scientists\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;ML Research Engineers\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;ML Engineers\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Computational Chemists\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Technical Project/Program Managers\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Or general applications.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;text-decoration: underline;\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Please note:\u0026lt;/strong\u0026gt; \u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you have previously registered your details we will be in touch if/when something suitable opens up - you do not need to reapply.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are receiving huge levels of interest so our response may not be immediate, however, if a relevant role opens up, we\u0026#39;ll be sure to reach out and connect.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Thank you for your interest in Iso Labs!\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6222901004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5228263004,"location":{"name":"London"},"metadata":null,"id":6222901004,"updated_at":"2026-10-13T08:47:13-04:00","requisition_id":"501","title":"Head of External Drug Discovery Operations, London","company_name":"Isomorphic Labs","first_published":"2026-10-13T08:23:18-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About the External Drug Discovery Operations team\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are establishing a new, centralised External Drug Discovery Operations group to serve as the operational engine for all externalised wet-lab research across Isomorphic Labs. Partnering directly with Drug Discovery \u0026amp;amp; Medical Research (DDMR) and Data Generation teams, this centre of excellence orchestrates, oversees, and scales our global Contract Research Organisation (CRO) footprint. Comprising CRO Scientific Leads, CRO Operations Managers, and Compound Managers, the team ensures high-throughput, high-fidelity data generation.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;The Head of External Drug Discovery Operations is a highly impactful role to drive and optimise how we utilise external partners to accelerate our pipeline delivery. You will lead all externalised drug discovery and preclinical laboratory activities, bridging wet-lab execution and enterprise data strategy. You will design, establish, and scale a modern CRO infrastructure tailored for an AI-first drug design platform, ensuring external workflows yield structured metadata, standardised assays, and automated ingestion pipelines across diverse therapeutic modalities. In partnership with DDMR leadership, you will shape long-term external sourcing strategies to maximise operational agility, experimental quality, and cycle time reduction. You will lead a dedicated team of CRO Scientific Leads, CRO Operations Managers, and Compound Managers, fostering a culture of technical and operational excellence, and cross-functional collaboration with our project teams.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead CRO operational strategy and execution: Oversee all external drug discovery and preclinical operations, driving accountability for experimental throughput, data quality control (QC), and end-to-end turnaround times to feed internal computational pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embed AI-first data architecture: Partner with Data Engineering and Informatics to mandate that external partner deliverables adhere to strict data-generation-by-design standards (standardised schemas, rich metadata capture, machine-readable formats, and direct pipeline integration).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strategic partner governance: Establish vendor selection criteria, governance tiers, and rigorous KPIs. Cultivate collaborative, high-trust relationships with key CROs while enforcing deliverables and rapidly resolving scientific or operational bottlenecks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Internal stakeholder alignment: Partner across our London, Boston and Lausanne sites with the Heads of Biology, Chemistry, DPC and DMPK/Safety to forecast resourcing demands, balance internal/external capacity, and translate project milestones into actionable external work packages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate novel platforms and technologies: In collaboration with Business Development and Discovery Leadership, scout, assess, and onboard emerging CRO capabilities and specialised experimental platforms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Commercial and budget stewardship: Collaborate with Procurement, Legal, and Finance to manage the external discovery budget, negotiate MSAs/rate cards, and streamline SOW generation and invoice reconciliation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build and mentor a talented, motivated team: Recruit, lead, and develop a high-performing team of CRO Scientific Leads, Operations Managers, and Compound Management professionals.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. or Master’s degree in Chemistry, Biology, Pharmacology, or a related life sciences discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Substantial industry track record of biopharma R\u0026amp;amp;D leadership, leading external research, discovery CRO management, or externalised discovery programs within biotech or pharma.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Technical breadth and working knowledge across medicinal/synthetic chemistry, in vitro screening cascades, in vivo pharmacology, and ADMET workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Data-centric operational delivery, with proven experience instituting structured data collection frameworks with external vendors, including automated QC, data curation protocols, and machine-readable data transfers.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Practical experience of deploying modern productivity tools and automated workflow systems to streamline external research operations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Commercial and financial acumen, with demonstrated success managing £multi-million discovery budgets, negotiating complex vendor agreements (MSAs/SOWs), and partnering with corporate Procurement and Legal functions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record of team leadership and influencing others in a matrix structure, including recruiting, mentoring, and organising operational teams while effectively driving alignment across cross-functional matrix leaders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with small molecules and complex or emerging modalities.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;AI-first mindset, with practical experience structuring chemical and biological data streams for machine learning workflows and automated DMTA cycles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exposure to or interest in applying agentic AI solutions to streamline external research operations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with biologics workflows.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/5578430004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":4949315004,"location":{"name":"London"},"metadata":null,"id":5578430004,"updated_at":"2026-10-12T09:21:24-04:00","requisition_id":"298","title":"ML Research Engineer, London","company_name":"Isomorphic Labs","first_published":"2025-07-04T06:54:30-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;strong\u0026gt;Research Engineering (Machine Learning), London\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;We are looking for Research Engineers with different levels of experience - Senior, Staff, Principal or equivalent levels.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;This is an exciting opportunity for you to contribute to frontier research at the intersection of AI and drug design.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;Working in a highly creative, iterative environment, you will be partnering with scientists and engineers to advance foundational models that will transform the biopharmaceutical world as we know it.\u0026amp;nbsp; \u0026lt;br\u0026gt;\u0026lt;br\u0026gt;You will draw upon your existing engineering and Machine Learning experience whilst learning from those around you, to apply novel techniques and ideas to newly encountered computational biology and chemistry problems.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Implementation \u0026amp;amp; Optimisation:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Translate research concepts into practical implementations by developing and optimising state-of-the-art AI models, and building and maintaining robust codebases, data pipelines, and infrastructure for training and evaluation.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Experimentation \u0026amp;amp; Evaluation:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design, implement, and run experiments to evaluate the performance and robustness of ML models, using a full spectrum of state-of-the-art machine learning methods. Evaluating, tuning, and maintaining AI/ML models (which includes collecting and preparing data as needed)\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Evaluation \u0026amp;amp; Inference:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Implement algorithms and software to analyse and evaluate the performance of AI models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Optimising performance of AI/ML models such as Diffusion models, Transformers, GNNs, leveraging a deep understanding of the AI/ML hardware+software stack\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Advise on how to bring AI/ML models to production and/or integrating them into product offerings, and monitoring and refining their behavior.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Developing specialised tools/frameworks/infrastructure to aid in the work above\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; Knowledge Sharing:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Work closely with research scientists and engineers, contributing to team discussions, sharing knowledge, and actively participating in code reviews to foster a collaborative environment.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Innovation \u0026amp;amp; Impact:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Proactively identify and address technical challenges, stay updated on the latest AI advancements, and focus on developing solutions that enable scaling our wider foundation and applied model platforms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to execute on independent engineering projects and software development towards research goals.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Industry Experience: 4+ years of experience working in reputable tech companies or research labs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Academic Background: Advanced degree (Master’s or PhD) in a highly quantitative field (Computer Science, AI, Physics, Mathematics, etc.) or equivalent practical experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;ML Fundamentals: Deep understanding of machine learning principles and techniques.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Framework Expertise: Strong proficiency in deep learning frameworks such as JAX or PyTorch.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Modern Architectures: Hands-on experience building and working with modern model architectures (e.g., Transformers, GNNs, Diffusion Models).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Full ML Lifecycle: Experience taking models from conception to production (scoping, data analysis, training, debugging, evaluation, benchmarking, and deployment).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Engineering Excellence: Excellent software development skills with strong algorithms and data structures fundamentals.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaboration \u0026amp;amp; Communication: An excellent team player with strong written and verbal communication skills, able to collaborate seamlessly in a cross-disciplinary environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Agency: Self-directed with an ability to navigate ambiguity, propose and own complex projects, learn the necessary context, and readily adapt to new domains and developments.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Nice to have\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Proven Research Record: A history of scientific contributions (e.g., publications at NeurIPS, ICML, ICLR, CVPR) or significant contributions to state-of-the-art AI models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scale \u0026amp;amp; Performance: Experience training models across distributed systems (multi-GPU/multi-node) and optimising training and inference performance (e.g., XLA, Triton, CUDA, Pallas).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Domain Knowledge: A strong interest in, or knowledge of, biochemistry, computational biology, or drug discovery fundamentals.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Applied ML: Experience developing models developed for real-world applications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Infrastructure: Solid technical infrastructure knowledge and experience with low-level engineering (e.g., GCP, Kubernetes, Docker)\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044355004,"name":"ML Research","child_ids":[],"parent_id":null}],"offices":[{"id":4031081004,"name":"Lausanne ","location":"Lausanne, Vaud, Switzerland","child_ids":[],"parent_id":null},{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6240415004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5234578004,"location":{"name":"London"},"metadata":null,"id":6240415004,"updated_at":"2026-11-04T05:28:28-05:00","requisition_id":"511","title":"Operating Partner (AI Research), London","company_name":"Isomorphic Labs","first_published":"2026-11-04T05:28:28-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As an Operating Partner you\u0026#39;ll work as a member of a compact, agile, and high-impact team specialising in catalysing business critical initiatives across Iso through partnership with cross-functional organisational leaders. Together, we drive operational excellence, maximising productivity and accelerating progress toward our mission. Because agility, organisation, and flawless execution are critical, this role will dynamically evolve alongside the needs of our team and the leaders you partner with.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;You’ll work alongside the VPs of AI and their wider organisation to deliver the highest-priority initiatives in their org areas, in particular where these are strategic in nature, require cross-organisational influence or are outside of the normal rhythms of the business.\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Thought-Partner:\u0026lt;/strong\u0026gt; You’ll enable leaders and their teams to operate effectively by advising and soundboarding on their ideas for how to solve problems, accelerate, and maximise outputs across their organisation\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Prioritise and Coordinate:\u0026lt;/strong\u0026gt; You will distinguish critical leadership priorities from support tasks, establishing clear ownership and empowering teams to act. With a keen sense of timing, you will know when to revive paused initiatives, align stakeholders, and deliver actionable plans.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Deliver and Execute:\u0026lt;/strong\u0026gt; You’ll focus your time on maximising the impact of key initiatives, particularly those outside the normal day-to-day operating patterns, or of the highest strategic importance. You’ll prepare, present and gain agreement on proposals among stakeholders and then influence teams to execute - leveraging strong communication skills. You’ll follow up, problem-solve, close loops in a timely fashion and drive initiatives to completion.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Drive Cross-Functional Collaboration:\u0026lt;/strong\u0026gt; You’ll build relationships with key stakeholders across Iso to gain a holistic understanding of the organisation, instilling high levels of trust and providing hands-on partnership on important projects.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Translate and Communicate:\u0026lt;/strong\u0026gt; You’ll translate complex technical developments into clear, high-impact executive summaries and strategic presentations for a variety of stakeholders, including board meetings and key management presentations.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Drive efficiency: \u0026lt;/strong\u0026gt;You’ll empower others to be maximally efficient by optimising for leanness and proactively spotting and breaking down blockers and inefficiencies, balancing what the organisation needs in the short and longer term with a keen eye for how to scale most efficiently and effectively.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Executive Partnership \u0026amp;amp; Thought Leadership: Proven track record of operating shoulder-to-shoulder with senior executive leaders (e.g., C-Suite, VP-level) as a trusted advisor, strategic soundboard, and operational force-multiplier.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understand and Translate Complex Topics with Fluency: Strong ability to learn and absorb technical information, grasp key concepts of machine learning/frontier AI, with the confidence to probe, synthesize, and translate complex technical matters into actionable executive communication.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Complex Execution \u0026amp;amp; Ambiguity: Demonstrated ability to break down highly ambiguous, multi-faceted problems into concrete plans and drive them through to measurable completion with pace and precision.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Cross-Functional Influence: Proven ability to build rapid trust and drive alignment across diverse, interdisciplinary teams (research, engineering, product, and operations) without direct line authority.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Agility \u0026amp;amp; Low-Ego Mindset: High resilience and adaptability in dynamic scale-up environments, with a roll-up-your-sleeves mentality where no task is too big or too small.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Background in a Chief of Staff, Strategic Operations, or Operating Partner role within a fast-scaling tech or AI organization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity or working exposure to digital biology, computational chemistry, or biopharma workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience facilitating executive team rhythms, planning cycles, and organizational scaling mechanisms.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044359004,"name":"Business Development","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6184829004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5211964004,"location":{"name":"London"},"metadata":null,"id":6184829004,"updated_at":"2026-09-08T05:50:17-04:00","requisition_id":"478","title":"Research Engineer (LLM Performance), London","company_name":"Isomorphic Labs","first_published":"2026-09-08T05:48:51-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;This is an exciting opportunity for you to contribute to frontier research at the intersection of AI and drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Working in a highly creative, iterative environment, you will join the model performance and scaling team, where you will partner with scientists and engineers to scale foundational models that will transform the biopharmaceutical world as we know it.\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will draw upon your existing engineering experience whilst learning from those around you, to apply novel techniques and ideas to newly encountered model and systems performance optimizations, as well as machine learning, computational biology and chemistry problems.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Implement and optimize LLM post-training methods at scale on frontier models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with research teams to translate new methods into production-ready systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Relentlessly prioritize and execute on performance optimization opportunities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate and deploy frameworks for supervised fine-tuning, reinforcement learning and LLM evaluation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Diagnose and fix performance bottlenecks and communication overhead in distributed training and inference systems.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deploy low-precision methods to balance performance with accuracy, impacting real world drug design programs.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Significant experience with large scale distributed training of LLMs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with deep learning ML frameworks (either JAX or PyTorch).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of parallelism strategies and collective communication libraries (e.g. NCCL).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Good understanding of GPU architectures. Reasoning about performance concepts is more important than writing kernels from scratch\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent collaboration skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with general LLM serving stacks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of XLA, Triton, Pallas, CUDA or similar accelerator DSLs / compilers.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with optimising ML accuracy using low-precision formats.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior experience building, deploying and maintaining production systems on GCP.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Interest in chemistry and biology.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044355004,"name":"ML Research","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6140840004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5198741004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6140840004,"updated_at":"2026-11-02T15:28:58-05:00","requisition_id":"461","title":"Research Leader (DMPK), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-09-03T12:09:23-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About the DMPK and Quantitative Pharmacology team\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;The DMPK and Quantitative Pharmacology team, part of the Preclinical Development group, accelerates the delivery of high quality drug candidates by developing innovative and creative AI-first solutions. By applying our domain expertise and through collaboration with the entirety of our world-class drug discovery disciplines and ML researchers, we ensure that drug-like properties are at the heart of our drug design engine. We shape the development of state-of-the-art ADME and toxicology predictive models. We rethink drug discovery from Hit ID to first-in-human (FIH) trials by optimising the context of use of these models.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;At Isomorphic Labs, DMPK Leads drive the DMPK strategy of drug discovery projects to deliver high quality clinical candidates whilst using and contributing to the optimisation of state-of-the-art computational and AI ADME models.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As part of the Drug Design and Medical Research team and through close collaboration with the Technology teams, you will be supporting the business alongside world leading AI/ML Drug Design Platform teams. You will collaborate to deliver scientific expertise and strategic direction to drive both improvements in the Platform and apply this to real drug design projects.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you are a skilled and ambitious scientist looking to take the next step in your career, joining Isomorphic Labs will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and implement stage-appropriate DMPK strategies with AI-first approach, integrating quantitative pharmacology and overall project strategies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design screening cascade and mechanistic experiments to support project progression in a data-driven manner.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate DMPK, PD and toxicological data to extract decision-making information, including dose and safety window predictions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define Quantitative Pharmacology strategy in collaboration with Pharmacology Leads.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Optimise the use of Iso’s datasets to address fundamental DMPK questions and advance the field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Optimise molecule design based on physico-chemistry and biotransformation knowledge in collaboration with Chemistry Leads.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain knowledge of state-of-the-art technologies and methods to increase confidence in human PK prediction.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author DMPK sections of regulatory documents.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace and champion a culture of inclusion and continuous professional development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in either Pharmaceutical Science, Pharmacy, Chemistry, or another relevant subject.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;7-10+ years’ professional experience in a DMPK role, operating within a biotech or pharma setting, solving small molecule DMPK-related problems in drug discovery with a track record of working collaboratively to deliver high quality candidates.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Practical experience developing DMPK and quantitative pharmacology packages to support early clinical development, including authoring and reviewing regulatory documents, ideally in oncology or immunology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of partnering closely with Preclinical and Clinical teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;In depth knowledge of biotransformation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;In depth knowledge of PK modelling and scaling of ADME properties.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with peptides and other new modalities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Advanced knowledge of PK/PD modelling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Good understanding of machine learning techniques.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with Python and R.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6240752004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5234721004,"location":{"name":"London"},"metadata":null,"id":6240752004,"updated_at":"2026-11-03T08:23:34-05:00","requisition_id":"512","title":"Research Leader / Senior Research Investigator (Computational Drug Design), London","company_name":"Isomorphic Labs","first_published":"2026-11-03T04:32:36-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;br\u0026gt;We’re hiring for our Computational Chemistry team across two different focus areas which are:\u0026amp;nbsp;\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026amp;nbsp;\u0026amp;nbsp;• Early-Stage \u0026amp;amp; Hit ID Specialist: Drive early portfolio target selection and progression and lead in silico hit-finding strategies.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026amp;nbsp;\u0026amp;nbsp;• Portfolio Specialist: Lead computational chemistry strategy across active portfolio programs, partnering with medicinal chemists to optimise leads toward candidate nomination.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Working as either a Program Lead or a Computational Chemistry Lead, you will provide scientific expertise and strategic direction for portfolio drug discovery projects, guiding them from initiation towards clinical candidate selection. Working alongside world-leading ML scientists, you will play a critical role in enhancing our AI platform through your technical expertise, and apply these improvements to drug design projects. You will have experience of working broadly across drug discovery projects, with the ability to think originally and critically, knowing when to apply innovative ideas, and think with a fresh approach. If you are a skilled Computational Chemist with a passion for applying cutting-edge technology to complex scientific challenges, this role offers an unparalleled opportunity for impact and growth.\u0026amp;nbsp;\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;As part of this hiring, some roles will have people management responsibilities for building teams of 2-3 Computational Chemists. In this case, you will be responsible for line managing and mentoring a talented and high-performing team, encouraging their scientific growth and career development. You’ll champion our cross-disciplinary approach, fostering a supportive team culture where continuous learning and the adoption of next-generation tools are the standard, not the exception.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Apply AI-first approaches to provide technical and strategic directions, and execute drug design programs. Take ownership as either an overall Program Lead or Computational Chemistry Lead.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate cross-functionally to support the data-driven delivery of high quality scientific solutions to complex technical problems\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish principles for embedding cutting-edge AI/ML into modern computational chemistry workflows, ensuring seamless integration across ML, Biology, and Chemistry teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide strategic input and technical direction to our ML platform teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Target Discovery: Successfully identify and validate therapeutic targets for early-stage portfolio projects\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;If Program Leadership: Champion the drug discovery pipeline, overseeing external collaborations (with CROs) and leading programs to meet critical go/no-go milestones. Prepare detailed scientific proposals and reports to support new and ongoing programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace and champion our culture of inclusion and continuous professional development.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Computational Chemistry, or a related scientific field, or equivalent industrial experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ / 5+ years of professional experience in a Computational Drug Design role, operating within a biotech, pharma or CRO setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record of project leadership / leading computational chemistry efforts on drug discovery programs, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in writing and implementing Python scripts for analysis and tool development, and/or utilising pipelining tools to support cheminformatics and design workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A genuine passion for drug discovery and enthusiasm for the potential of ML to transform the field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior experience leveraging machine learning and generative AI methods for hit finding (e.g. ultra-large virtual screening and active learning), molecular design and lead optimisation (e.g. REINVENT, cofolding and AI-powered ligand/pose scoring methods).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;For a people / program management position: experience of leading a high-performing scientific team, mentoring and empowering them to thrive in their roles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong track record of scientific achievements, evidenced by publications, patents, and presentations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication (written and verbal) and interpersonal skills, with an ability to work effectively in a cross- functional, collaborative team environment.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of strategic thinking and creative problem solving with a strong growth mindset, adaptability, and eagerness to learn new concepts and techniques.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with using frontier large language models and systems\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of other specific drug discovery approaches like fragment-based drug design (FBDD), and alternative modalities like PROTACs, molecular glues, PPI inhibitors or stabilisers, peptides etc.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understanding of drug metabolism and pharmacokinetics (ADME + DMPK) principles.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6140838004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5198739004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6140838004,"updated_at":"2026-08-28T14:57:54-04:00","requisition_id":"463","title":"Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-08-28T14:57:54-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About the Applied Computational Drug Design team\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are a dynamic team of Computational Chemists transforming how drug discovery happens. By partnering deeply with our machine learning colleagues, we are doing more than just leveraging the Isomorphic Labs drug design engine - we are actively shaping it. We use our computational expertise to challenge and refine our algorithms, creating a powerful symbiotic relationship between data and computation that drives our internal and collaborative portfolios. Our team works closely together in a supportive environment, where everyone is valued for their computational chemistry expertise and the experience they bring to the group. We have a strong growth mindset and prioritise continued development and learning.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We’re hiring at the Research Leader and Senior Scientist levels, and you can apply for either position using the application form below. These roles are ideal for experienced computational chemists who are eager to shape the future of drug discovery at the intersection of computational chemistry and artificial intelligence.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Working as either a Program Lead or a Computational Chemistry Lead, you will provide scientific expertise and strategic direction for portfolio drug discovery projects, guiding them from initiation towards clinical candidate selection. Working alongside world-leading ML scientists, you will play a critical role in enhancing our AI platform through your technical expertise, and apply these improvements to drug design projects. You will have experience of working broadly across drug discovery projects, with the ability to think originally and critically, knowing when to apply innovative ideas, and think with a fresh approach. If you are a skilled Computational Chemist with a passion for applying cutting-edge technology to complex scientific challenges, this role offers an unparalleled opportunity for impact and growth.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As part of this hiring, some roles will have people management responsibilities for building teams of 2-3 Computational Chemists. In this case, you will be responsible for line managing and mentoring a talented and high-performing team, encouraging their scientific growth and career development. You’ll champion our cross-disciplinary approach, fostering a supportive team culture where continuous learning and the adoption of next-generation tools are the standard, not the exception.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Apply AI-first approaches to provide technical and strategic directions, and execute drug design programs. Take ownership as either an overall Program Lead or Computational Chemistry Lead.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate cross-functionally to support the data-driven delivery of high quality scientific solutions to complex technical problems\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish principles for embedding cutting-edge AI/ML into modern computational chemistry workflows, ensuring seamless integration across ML, Biology, and Chemistry teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide strategic input and technical direction to our ML platform teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;If Program Leadership: Champion the drug discovery pipeline, overseeing external collaborations (with CROs) and leading programs to meet critical go/no-go milestones.\u0026lt;br\u0026gt;Prepare detailed scientific proposals and reports to support new and ongoing programs.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace and champion our culture of inclusion and continuous professional development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Computational Chemistry, or a related scientific field, or equivalent industrial experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ / 5+ years of professional experience in a Computational Drug Design role, operating within a biotech, pharma or CRO setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record of project leadership / leading computational chemistry efforts on drug discovery programs, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in writing and implementing Python scripts for analysis and tool development, and/or utilising pipelining tools to support cheminformatics and design workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A genuine passion for drug discovery and enthusiasm for the potential of ML to transform the field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;For a people / program management position: experience of leading a high-performing scientific team, mentoring and empowering them to thrive in their roles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong track record of scientific achievements, evidenced by publications, patents, and presentations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication (written and verbal) and interpersonal skills, with an ability to work effectively in a cross-functional, collaborative team environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of strategic thinking and creative problem solving with a strong growth mindset, adaptability, and eagerness to learn new concepts and techniques.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Prior experience leveraging machine learning and generative AI methods for hit finding (e.g. ultra-large virtual screening and active learning), molecular design and lead optimisation (e.g. REINVENT, cofolding and AI-powered ligand/pose scoring methods).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of other specific drug discovery approaches like fragment-based drug design (FBDD), and alternative modalities like PROTACs, molecular glues, PPI inhibitors or stabilisers, peptides etc.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understanding of drug metabolism and pharmacokinetics (ADME + DMPK) principles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Fluency in Python with ability to write code for new tools.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of authorship of relevant scientific manuscripts and/or inventorship of composition of matter patents.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with or managing activities at contract research organisations (CROs).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6131996004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5194384004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6131996004,"updated_at":"2026-08-11T11:47:41-04:00","requisition_id":"451","title":"Research Leader / Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-07-31T12:56:27-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic labs are seeking exceptional individuals to join a highly impactful In vitro and Cellular Pharmacology sub-team, within our Translational Sciences team, which specialises in small molecules. We’re hiring at the Research Leader and Senior Scientist levels, and you can apply for either position using the application form below.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;These roles are ideal for experienced in vitro pharmacologists with significant working knowledge of biophysical, biochemical and/or cell-based functional assays, and extensive experience of providing quantitative in vitro pharmacology expertise within drug discovery projects. You will be responsible for defining in vitro strategies and screening cascades for our drug design projects, advancing our oncology, immunology and partnership portfolios from early drug discovery through to candidate selection, and ultimately to clinical phase work. These are exciting opportunities to work closely with world-leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions to drive our projects forward. By overseeing externalized CRO activities, you will close the loop between computational biological insights and real-world laboratory validation. You will have experience of working broadly across drug discovery projects, with the ability to think originally and critically, knowing when to apply innovative ideas, and think with a fresh approach. If you are a skilled In vitro / Cellular Pharmacologist with a passion for applying cutting-edge technology to complex scientific challenges, this role offers an unparalleled opportunity for impact and growth.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As part of this hiring, some roles will have people management responsibilities for building teams of 2-3 In vitro / Cellular Pharmacologists. In this case, you will be responsible for line managing and mentoring a talented and high-performing team, encouraging their scientific growth and career development. You’ll champion our cross-disciplinary approach, fostering a supportive team culture where continuous learning and the adoption of next-generation tools are the standard, not the exception.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design efficient and comprehensive biological screening cascades for a variety of internal and partnered drug design programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Guide the optimization and implementation of biophysical and biochemical assays, including SPR, ITC, and enzymatic methodologies, to rigorously evaluate target interaction, pharmacological potency, and molecular specificity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Direct the development and refinement of functional and phenotypic cellular assays, bridging the gap between biochemical engagement and biological potency to advance target validation and mechanistic understanding.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work with CROs to design decision-making experiments, and deliver the highest quality biological data to inform the path to the clinic.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate, interpret, and synthesize complex binding, kinetic, and dose-response information; generate precise technical documentation to guide strategic decision-making and support IND-enabling data packages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Act as a vital bridge between computational prediction and experimental reality, collaborating closely with:\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;AI/ML and Data Science teams: To translate in silico predictions into testable hypotheses and provide clean data loops to train future models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Medicinal Chemistry: To guide SAR-driven design cycles with rapid, reliable potency and selectivity data.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Structural Biology: To align biophysical binding data with structural insights informing lead optimization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;In vivo Pharmacology and Translational Sciences: To ensure a seamless handoff of validated leads into in vivo efficacy and translational study design.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026amp;nbsp;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. in Pharmacology, Biochemistry, Cell Biology, Biophysics, or a related scientific discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ years / 5+ years of professional experience in a Translational Sciences role, operating within a biotech, pharma or CRO setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of project leadership / leading biology within small molecule drug discovery programs, ideally from inception to clinical candidate delivery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;For a people management position, experience of leading a high-performing scientific team, mentoring and empowering them to thrive in their roles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Extensive experience in the design and implementation of biological screening cascades applied to drug design projects from hit identification to candidate selection phases.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep knowledge of experimental in vitro pharmacology techniques including biophysical, biochemical and/or cellular assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to provide technical guidance within matrixed organizations, effectively steering cross-functional programs and execution through collaboration.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with CROs in acquiring and interpreting high quality biological data in a timely manner.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Dynamism and agility, with ability to work across several projects and therapeutic areas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Effective communication across a broad interdisciplinary team, working with key stakeholders with different skills and backgrounds.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience of leading biology within drug discovery programs from inception to clinical candidate delivery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience partnering with Data Science groups in setting up systems for ingestion of biological data.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of contributing to drug design projects which have then delivered Clinical Candidates.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of designing and implementing assays and screening cascades for alternative modalities or alternative chemistries e.g peptides or molecular glues.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;General knowledge of machine learning modelling applied to biological systems and drug discovery.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6132115004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5194420004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6132115004,"updated_at":"2026-08-11T11:58:15-04:00","requisition_id":"452","title":"Research Leader / Senior Scientist (In vivo Pharmacology \u0026 Translational Sciences), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-07-31T13:37:59-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic labs are seeking exceptional individuals to join a highly impactful Translational Biology sub-team, within our Translational Sciences team, which specialises in small molecules. We’re hiring at the Research Leader and Senior Scientist levels, and you can apply for either position using the application form below.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;These roles are ideal for experienced translational biologists with a skill for designing fit-for-purpose screening cascades to provide robust experimental evidence that our ML-designed medicines will have the desired therapeutic product profiles (TPPs). You will be responsible for establishing and implementing translational strategies, advancing our oncology, immunology and partnership portfolios from early drug discovery through to candidate selection and ultimately to clinical phase work. These are exciting opportunities to work closely with world leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions in disease to drive our projects forward. By overseeing externalized CRO activities, you will close the loop between computational biological insights and real-world laboratory validation. You will have experience of working broadly across drug discovery projects, with the ability to think originally and critically, knowing when to apply innovative ideas, and think with a fresh approach. If you are a skilled In vivo Pharmacologist with a passion for applying cutting-edge technology to complex scientific challenges, this role offers an unparalleled opportunity for impact and growth.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As part of this hiring, some roles will have people management responsibilities for building teams of 2-3 In vivo Pharmacologists. In this case, you will be responsible for line managing and mentoring a talented and high-performing team, encouraging their scientific growth and career development. You’ll champion our cross-disciplinary approach, fostering a supportive team culture where continuous learning and the adoption of next-generation tools are the standard, not the exception.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026amp;nbsp;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Oversee the comprehensive planning, methodology development, fiscal management, and implementation of target-specific in vitro and in vivo pharmacology, PK/PD, and safety assessments throughout our project portfolios.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design robust translation strategies explicitly geared toward clinical translation, leveraging datasets and biomarkers to inform patient selection frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Play a critical role in defining the most appropriate model paradigm (in vivo, ex vivo patient-derived tissue etc) for each project’s translational package, including developing a biomarker strategy to deliver early clinical proof of concept.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work with CROs to design decision-making experiments, and deliver the highest quality biological data to inform the path to the clinic.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide scientific expertise to the ML and computational biology teams, to support the development of world-leading models of biological systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Distill biological data into useful insights and recommendations for project leaders, project team members, and partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Be closely integrated within or lead projects to provide strategic input to deliver project success.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyze and interpret experimental data to deliver high-quality reports that drive go/no-go decisions and support IND regulatory filings.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Act as a vital bridge between computational prediction and experimental reality, collaborating closely with:\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;ML and Data Science Teams: To translate in silico predictions into physical validation protocols and provide clean data loops to train future models, iteratively improving the predictive accuracy of our proprietary drug design platform.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Discovery Biology and Lead Optimization: To seamlessly transition hits generated by our drug design engine into advanced preclinical characterization and guide SAR-driven design cycles with rapid, reliable preclinical efficacy data.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;DMPK and Toxicology: To align in vivo efficacy with ADME and exposure data, informing safety windows and dose selection.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Clinical Development and Program Management: To translate preclinical PK/PD hypotheses into first-in-human trial designs, biomarker strategies, and patient inclusion criteria.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. in Pharmacology, Immunology, Cancer Biology, Molecular Biology, or a related scientific discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ years / 5+ years of professional experience in a Translational Sciences role, operating within a biotech, pharma or CRO setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of project leadership / leading biology within small molecule drug discovery programs, ideally from inception to clinical candidate delivery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;For a people management position, experience of leading a high-performing scientific team, mentoring and empowering them to thrive in their roles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep understanding of target, mechanism, and disease interdependencies, with expert knowledge of innovative translational models in oncology and/or immune disorders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Extensive pharma/biotech experience developing Target Product Profiles (TPPs) and converting them into biological screening cascades, to guide impactful drug development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record in constructing translational data packages and biomarker strategies to inform clinical trial design.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in designing PK/PD experiments for human dose prediction and phasing translational biology activities collaboratively with ADMET, formulation, and clinical specialists.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record managing multi-vendor CRO networks, including contract negotiation, timeline accountability, and data quality oversight.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exceptional project management and leadership skills, with the ability to lead and influence matrixed teams without direct authority and manage multiple complex external studies simultaneously.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Dynamism, agility, and effective communication across broad interdisciplinary teams and key stakeholders with diverse backgrounds.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Track record of driving strategic de-risking and SAR strategies, collaborating effectively across disciplines, including medicinal chemistry and DMPK. Good understanding of medicinal chemistry concepts.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;General knowledge of machine learning modelling applied to biological systems and drug discovery.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6140839004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5198740004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6140839004,"updated_at":"2026-08-11T11:26:57-04:00","requisition_id":"462","title":"Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-08-11T11:18:15-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About the Medicinal Drug Design team\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are a dynamic team of Medicinal Chemists transforming how drugs are designed. By partnering deeply with our machine learning colleagues, we are doing more than just leveraging the Isomorphic Labs drug design engine - we are actively shaping it. We use our domain expertise to challenge and refine our algorithms, creating a powerful symbiotic relationship that drives our internal and collaborative portfolios. Our team works closely together in a supportive environment, where everyone is valued for their medicinal chemistry expertise and the experience they bring to the group. We have a strong growth mindset and prioritise continued development and learning.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We’re hiring at the Research Leader and Senior Scientist levels, and you can apply for either position using the application form below. These roles are ideal for experienced medicinal chemists who are eager to shape the future of drug discovery at the intersection of medicinal chemistry and artificial intelligence.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Working as either a Project Lead or a Medicinal Chemistry Lead, you will provide scientific expertise and strategic direction for portfolio drug discovery projects, guiding them from initiation towards clinical candidate selection. Working alongside world-leading ML scientists, you will play a critical role in enhancing our AI platform through your technical expertise, and apply these improvements to drug design projects. You will have experience of working broadly across drug discovery projects, with the ability to think originally and critically, knowing when to apply innovative ideas, and think with a fresh approach. If you are a skilled Medicinal Chemist with a passion for applying cutting-edge technology to complex scientific challenges, this role offers an unparalleled opportunity for impact and growth.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As part of this hiring, some roles will have people management responsibilities for building teams of 2-4 Medicinal Chemists. In this case, you will be responsible for line managing and mentoring a talented and high-performing team, encouraging their scientific growth and career development. You’ll champion our cross-disciplinary approach, fostering a supportive team culture where continuous learning and the adoption of next-generation tools are the standard, not the exception.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Invent new medicines. Rapidly drive drug discovery programs to value inflection points by deploying your knowledge of modern discovery principles and synthetic organic chemistry, taking ownership as either an overall Project Lead or Medicinal Chemistry Lead.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate cross-functionally to support the data-driven delivery of high quality scientific solutions to complex technical problems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Represent the company externally, interacting with existing and prospective collaborators and Contract Research Organisations (CROs).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide strategic input and technical direction to our ML platform teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Effectively manage CRO resources and monitor KPIs to maintain delivery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Generate intellectual property positions and capture the value derived from IsoLabs’ investment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prepare detailed scientific proposals and reports to support new and ongoing programs.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace and champion our culture of inclusion and continuous professional development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Medicinal Chemistry, Synthetic Organic Chemistry, or a related technical field, or equivalent industrial experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ / 5+ years of professional experience in a Medicinal Chemistry role, operating within a biotech, pharma or CRO setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record of project leadership / leading medicinal chemistry efforts on drug discovery projects, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination), with familiarity of optimisation of ADME properties.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;For a people management position, experience of leading a high-performing scientific team, mentoring and empowering them to thrive in their roles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of driving a problem through structure-based drug design.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent strategic thinking, problem-solving, and decision-making capabilities applied to complex drug discovery challenges.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of working with and closely managing CRO resources.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong track record of scientific achievements, evidenced by publications, patents, and presentations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A genuine passion for drug discovery and enthusiasm for the potential of ML to transform the field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication (written and verbal) and interpersonal skills, with an ability to work effectively in a cross-functional, collaborative team environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of creative problem solving with a strong growth mindset, adaptability, and eagerness to learn new concepts and techniques.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience of successful application of fragment-based drug design approaches.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6188302004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5213069004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6188302004,"updated_at":"2026-11-02T13:40:50-05:00","requisition_id":"481-1","title":"Research Leader (Toxicology), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-09-11T04:33:48-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About the Preclinical Development team\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;The Preclinical Development team accelerates the delivery of high quality candidates by developing innovative and creative AI-first solutions. Through collaboration with the entirety of the drug discovery disciplines and the ML researchers, we ensure that safety, druggability and developability are at the heart of our drug design engine. We shape the development of state-of-the-art toxicology predictive models. We rethink drug discovery from HitID to First in Human trials by optimising the context of use of these models.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As a Toxicology Lead, you will develop the safety assessment strategy of drug discovery and development projects from inception to regulatory submission. Working closely with the drug design platforms (small molecules and biologics), you will drive the optimisation of Iso’s assets with an AI-first approach in mind. In addition, you will guide the development of our AI predictive toxicology platform in order to increase the probability of success of Iso’s assets and contribute to the reduction of animal testing in drug discovery, in collaboration with the AI/ML research and data strategy teams.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you are an experienced, innovative and ambitious scientist looking to play an active part in the AI-driven transformation of the pharmaceutical industry, joining Isomorphic Labs will lift you out of your comfort zone and provide an amazing opportunity for personal growth and development.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Discovery and development support\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and implement safety assessment strategies with an AI-first approach to support small molecules and biologics drug discovery projects.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design screening cascades and mechanistic experiments to support project progression in a data-driven manner.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop SAR understanding of toxicology main liabilities to optimise chemical and biological matter where needed.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define regulatory safety assessment packages to support successful acceptance by regulatory agencies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author toxicology sections of regulatory documents.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Predictive toxicology strategy\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Partner with Machine Learning colleagues to build the predictive toxicology aspects of the drug design platform and identify, generate and analyse data from which to develop and improve predictive toxicology models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify state-of-the-art technologies and methods that could bring transformational benefits to our platform or ways of working.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;CRO interactions\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Since Isomorphic Labs outsource all wet-lab work to external vendors, you will maintain and develop close relationships with the CRO network to:\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ensure high quality and timely data generation to support our portfolio projects.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leverage the scientific expertise of our external collaborators to enhance the team\u0026#39;s impact.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee the delivery of data generation campaigns purposefully designed to support the development of AI-based toxicology models.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;People\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Mentor junior members of the team.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace and champion a culture of inclusion and continuous professional development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. in Toxicology, Pharmacology, Biology, or DVM/MD with relevant experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Board Certification.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Extensive professional experience working in a senior toxicology role across different therapy areas within the biotech or pharma setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience filing successful INDs/CTAs for both small molecules and biologics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep understanding of Global Regulatory Guidelines regarding safety assessment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of partnering closely with Discovery and Clinical teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication (written and verbal), interpersonal and influencing skills, with an ability to work effectively in a cross-functional, collaborative team environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of creative problem solving with a strong growth mindset, adaptability, willingness to challenge conventional thinking and eagerness to learn new concepts.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with peptides and other new modalities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Good understanding of machine learning techniques.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with Python and KNIME.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6230745004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5230961004,"location":{"name":"London"},"metadata":null,"id":6230745004,"updated_at":"2026-10-21T06:37:03-04:00","requisition_id":"503","title":"Research Leader (Toxicology), London","company_name":"Isomorphic Labs","first_published":"2026-10-21T06:17:24-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About the Toxicology team\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;The Toxicology team operates at the cutting-edge intersection of preclinical development and artificial intelligence, redefining how safety is assessed from the very beginning of the drug discovery process. Through collaboration with drug program teams, subject matter experts and ML researchers, we ensure that safety is a key pillar of our drug design engine. We shape the development of state-of-the-art toxicology predictive models, optimising their context of use to rethink drug discovery from HitID to First in Human trials.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As a Research Leader (Toxicology), you will own the safety assessment strategy of specific drug discovery and development projects from inception to regulatory submission. Working closely with the drug design platforms (small molecules and biologics), you will drive the optimisation of Iso’s assets with an AI-first approach in mind. In addition, you will guide the development of our AI predictive toxicology platform in order to increase the probability of success of Iso’s assets and contribute to the reduction of animal testing in drug discovery, in collaboration with the AI/ML research and data strategy teams.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you are an experienced, innovative and ambitious project toxicologist looking to play an active part in the AI-driven transformation of the pharmaceutical industry, joining Isomorphic Labs will lift you out of your comfort zone and provide an amazing opportunity for personal growth and development.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Portfolio deliverables\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;As a core member of project teams, tailor and implement project-specific safety assessment strategies with an AI-first approach to support small molecules and biologics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design screening cascades and mechanistic experiments to elucidate and mitigate safety risks, supporting project progression in a data-driven manner.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide technical expertise to develop SAR understanding of toxicology liabilities to enable optimisation of chemical and biological matter.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define regulatory safety assessment packages to support successful acceptance by regulatory agencies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Communicate clear integrated risk assessments and recommendations to internal stakeholders\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author and defend toxicology sections of regulatory documents.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;CRO interactions\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Since Isomorphic Labs outsource all wet-lab work to external vendors, you will maintain and develop close relationships with the CRO network to:\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ensure high quality and timely data generation to support our portfolio projects.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leverage the scientific expertise of our external collaborators to enhance the team\u0026#39;s impact.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee the delivery of data generation campaigns purposefully designed to support the development of AI-based toxicology models.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;People\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Empower fellow team members by sharing your expertise in toxicology, fostering a culture of continuous learning and mutual support.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace and champion a culture of inclusion and continuous professional development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Toxicology, Pharmacology, Biology, or related technical field, or equivalent industrial experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ years of professional experience working in a senior toxicology role within a biotech or pharma setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record of delivering successful non-clinical safety strategies as a project representative across different therapy areas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience designing, implementing and filing successful IND packages for both small molecules and biologics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep understanding of Global Regulatory Guidelines regarding safety assessment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of partnering closely with Discovery and Clinical teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication (written and verbal), interpersonal and influencing skills, with an ability to work effectively in a cross-functional, collaborative team environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of creative problem solving with a strong growth mindset, adaptability, willingness to challenge conventional thinking and eagerness to learn new concepts.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Board certification\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with peptides and other new modalities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Good understanding of the application of AI/ML techniques in drug discovery\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6235913004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5232678004,"location":{"name":"London"},"metadata":null,"id":6235913004,"updated_at":"2026-10-27T06:57:19-04:00","requisition_id":"508","title":"Research Lead (Formulation Sciences), London ","company_name":"Isomorphic Labs","first_published":"2026-10-27T06:44:40-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As part of the ongoing expansion of our Drug Design and Medical Research function (DDMR), we are looking to recruit a Formulation expert keen to impact drug discovery project\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will be supporting the business alongside world leading AI/ML Drug Design Platform teams. You will collaborate to deliver scientific expertise and strategic direction to drive both improvements in the Platform and apply this to real drug design projects.\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a member of the DPC and Preclinical formulation team, you will be responsible for supporting the rapid progression of multiple drug discovery/DPC and preclinical development projects by providing (pre)-formulation expertise to the program team leveraging significant external CRO resources.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you are a skilled and ambitious scientist looking to take the next step in your career, joining the Isomorphic Labs now will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.\u0026amp;nbsp;\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop and execute comprehensive (pre)-formulation strategies for small molecules across the drug discovery and preclinical development lifecycle working closely with the drug design, pre-clinical and CMC function.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and refine innovative formulation technologies, such as solid dispersions and co-crystals, to optimise solubility, stability, and manufacturability.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and interpret stability studies utilising ICH and ASAP methodologies, while implementing rigorous in-process controls to ensure product performance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate across multi-disciplinary preclinical teams to deliver seamless and integrated solutions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author technical reports, protocols, and regulatory submissions in strict alignment with internal policies and global regulatory requirements.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in pharmaceutical science, or a related technical field, or equivalent experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;6+ years of professional experience within a biotech or pharma setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated expertise in the development of oral solid dosage forms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience of supporting IND packages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep technical proficiency in preformulation, manufacturing processes, and the implementation of advanced drug delivery technologies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Rigorous understanding of global regulatory guidelines, including ICH and FDA.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication (written and verbal), interpersonal and influencing skills, with an ability to work effectively in a cross-functional, collaborative team environment.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Specialised knowledge and practical experience in the development of amorphous dispersions is highly advantageous.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6237340004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5233270004,"location":{"name":"London"},"metadata":null,"id":6237340004,"updated_at":"2026-10-28T06:43:20-04:00","requisition_id":"509","title":"Research Lead / Senior Scientist (DMPK), London","company_name":"Isomorphic Labs","first_published":"2026-10-28T06:43:20-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;At Isomorphic Labs, DMPK Leads drive the DMPK strategy of drug discovery projects to deliver high quality clinical candidates whilst using and contributing to the optimisation of state-of-the-art computational and AI ADME models.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As part of the Drug Design and Medical Research team and through close collaboration with the Technology teams, you will be supporting the business alongside world leading AI/ML Drug Design Platform teams. You will collaborate to deliver scientific expertise and strategic direction to drive both improvements in the Platform and apply this to real drug design projects.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you are a skilled and ambitious scientist looking to take the next step in your career, joining Isomorphic Labs will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with biologics, peptides and other new modalities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define and implement stage-appropriate DMPK and ADME strategies across multiple modalities\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Utilise state-of-the-art modelling (e.g., ML/AI and PBPK) to extrapolate preclinical data and predict human dosing, efficacy, and safety windows\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experienced author and reviewer of DMPK regulatory documents and experience in responding to regulatory queries\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and implement stage-appropriate DMPK strategies with AI-first approach, integrating quantitative pharmacology and overall project strategies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design screening cascade and mechanistic experiments to support project progression in a data-driven manner.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate DMPK, PD and toxicological data to extract decision-making information, including dose and safety window predictions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define Quantitative Pharmacology strategy in collaboration with Pharmacology Leads.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Optimise the use of Iso’s datasets to address fundamental DMPK questions and advance the field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Optimise molecule design based on physico-chemistry and biotransformation knowledge in collaboration with Chemistry Leads.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain knowledge of state-of-the-art technologies and methods to increase confidence in human PK prediction.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author DMPK sections of regulatory documents.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embrace and champion a culture of inclusion and continuous professional development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in either Pharmaceutical Science, Pharmacy, Chemistry, or another relevant subject.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ years’ professional experience as a DMPK Lead, solving DMPK-related problems in drug discovery with a track record of working collaboratively to deliver high quality candidates.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in supporting DMPK across multiple modalities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comprehensive understanding of drug metabolism, pharmacokinetics, PKPD principles, and translational research.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Practical experience developing DMPK and quantitative pharmacology packages to support early clinical development, including authoring and reviewing regulatory documents, ideally in oncology or immunology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of partnering closely with Preclinical and Clinical teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated cross-functional leadership and exceptional interpersonal, communication, and collaborative problem-solving capabilities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;In depth knowledge of biotransformation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of utilising and applying NAMs to further project understanding\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strategic thinker with strong communication skills, capable of working across multiple disciplines\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Advanced knowledge of PKPD modelling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Good understanding of machine learning techniques.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with R, Python and KNIME.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/5704870004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5004960004,"location":{"name":"London"},"metadata":null,"id":5704870004,"updated_at":"2026-07-17T05:51:39-04:00","requisition_id":"335","title":"Research Scientist (Applied LLMs), London","company_name":"Isomorphic Labs","first_published":"2025-11-11T09:32:54-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Research Scientist - Applied Large Language Models\u0026lt;/strong\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As a Research Scientist focused on the application of Large Language Models (LLMs), you will play an exciting role in bringing cutting edge technologies to bear across our research areas to transform the drug discovery world as we know it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Working in a highly creative, fast-paced and interdisciplinary environment, you will be partnering with leading research scientists and engineers to conceive, design, and develop cutting edge LLM applications that help to unlock new modelling capabilities and predictive power which will be critical to the organisation’s success. You will draw upon your existing deep understanding and experience whilst learning from those around you, to apply novel techniques and ideas to newly encountered computational biology and chemistry problems.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Depending on your experience:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will both partner with teams across our existing research areas and create and lead standalone projects, bringing together a variety of disciplined scientists and engineers to pursue some of the most ambitious modelling problems through the application of LLMs - as well as providing technical mentorship and people management for others in the ML community at Isomorphic Labs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will be instrumental in leading machine learning based research projects, building the models, and algorithms that will power our platform to drive us close to achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Contribute to core research in machine learning by pushing the boundaries of Large Language Models in their application to the world of drug discovery\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and refine LLM-driven approaches for multiple use cases across our research areas, using your extensive knowledge of the field to modify and apply models and explore their capabilities when applied to complex biological and medical challenges.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify and create novel ML techniques and the required data to train and apply models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyse and tune experimental results to inform future experimental directions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Implement and scale training and inference engineering frameworks\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Report and present research findings and developments clearly and efficiently, to both other ML scientists and scientists of different disciplines\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Iterate collaboratively with scientists and domain experts, sharing your own domain experience\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Suggest and engage in team collaborations to meet ambitious research goals\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;strong\u0026gt;Depending on your experience:\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide technical mentorship and guidance to the ML research community, advising on projects, and shaping our research roadmap based on your deep technical expertise.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide developmental support to other ML research scientists.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Create, lead, and run ML research projects, fostering collaborative and diverse teams to solve high priority modelling problems. Cultivate a diverse and inclusive research culture.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Essential\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD or equivalent practical experience in a technical field\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Highly specialized LLM builder with a passion for, and strong experience in, applying LLMs to novel problem spaces\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep understanding and experience of model architectures, training methods, and techniques for application of LLMs, including deployment for bespoke use cases and applications, established experience in post-training, reasoning, test-time scaling, tool-use, alignment, agents, LLM research, as well as reinforcement learning and fine-tuning\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong knowledge of linear algebra, calculus and statistics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience using ML frameworks such as JAX, PyTorch, or TensorFlow, and scientific software such as NumPy, SciPy, or Pandas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Depending on your experience: project supervision, leadership, or management.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong knowledge of LLM landscape today, and likely developments for the near future\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with real-world datasets.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Nice to have\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in machine learning or computer science.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Relevant research experience to the position such as post doctoral roles, a proven track record of publications, or contributions to machine learning codebases.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A strong background in biology or medicine, enabling you to bridge the gap between advanced AI capabilities and complex scientific problems in drug discovery\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working in a scientific environment across disciplines (particularly biology, chemistry, physics), and with real world biological or chemical datasets and biological or chemistry software\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in computational chemistry, bioinformatics, or related fields would be highly beneficial, along with a track record of applying AI to real-world scientific challenges\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with multi-parameter optimization\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in any of: large scale deep learning, generative models, graph neural networks, deep learning for drug discovery, deep learning for computer vision, 3D graphics/robotics, real-world applied RL\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044355004,"name":"ML Research","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/5224363004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":4737295004,"location":{"name":"London"},"metadata":null,"id":5224363004,"updated_at":"2026-07-17T05:51:39-04:00","requisition_id":"184","title":"Research Scientist (Machine Learning), London","company_name":"Isomorphic Labs","first_published":"2024-07-06T07:00:52-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Research Scientist (Machine Learning), London\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As a Research Scientist in machine learning (ML), you will play an exciting role in building greenfield machine learning based models and algorithms that will power our platform to transform the drug discovery world as we know it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Working in a highly creative, fast-paced and interdisciplinary environment, you will be partnering with leading engineers and scientists to conceive, design, and develop cutting edge machine learning algorithms to unlock new modelling and predictive power which will be critical to the organisation’s success. You will draw upon your existing deep research experience whilst learning from those around you, to apply novel techniques and ideas to newly encountered computational biology and chemistry problems.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Depending on your experience:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will create and lead projects, bringing together a variety of disciplined scientists and engineers to pursue some of the most ambitious modelling problems with deep learning - as well as providing technical mentorship and people management for others in the ML community at Isomorphic Labs\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will be instrumental in leading greenfield machine learning based research projects, building the models, and algorithms that will power our platform to transform the drug discovery world as we know it.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Contribute to our research directions in machine learning by using your extensive knowledge of the field to apply world-leading ML algorithms to drug discovery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify and create novel ML techniques and the required data to train.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop the architectures and training algorithms of machine learning models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyse and tune experimental results to inform future experimental directions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Implement and scale training and inference engineering frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Report and present research findings and developments clearly and efficiently, to both other ML scientists and scientists of different disciplines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Iterate collaboratively with scientists and domain experts, sharing your own domain experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Suggest and engage in team collaborations to meet ambitious research goals.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;strong\u0026gt;Depending on your experience:\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide technical mentorship and guidance to the ML research community, advising on projects, and shaping our research roadmap based on your deep technical expertise.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide developmental support to other ML research scientists.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Create, lead, and run ML research projects, fostering collaborative and diverse teams to solve high priority modelling problems.Cultivate a diverse and inclusive research culture.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Essential\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD or equivalent practical experience in a technical field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A proven track record in machine learning using deep learning techniques, including designing new architectures, hands-on experimentation, analysis, and visualisation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong knowledge of linear algebra, calculus and statistics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience using ML frameworks such as JAX, PyTorch, or TensorFlow, and scientific software such as NumPy, SciPy, or Pandas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A passion for applying ML research to real world problems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Depending on your experience: project supervision, leadership, or management.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Nice to have\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in machine learning or computer science.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Relevant research experience to the position such as post doctoral roles, a proven track record of publications, or contributions to machine learning codebases.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working in a scientific environment across disciplines (particularly biology, chemistry, physics).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with biological or chemical data and biological or chemistry software.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with real-world datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with ML on accelerators.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in any of: large scale deep learning, generative models, graph neural networks, deep learning for drug discovery, deep learning for computer vision, 3D graphics/robotics, real-world applied RL.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044355004,"name":"ML Research","child_ids":[],"parent_id":null}],"offices":[{"id":4031081004,"name":"Lausanne ","location":"Lausanne, Vaud, Switzerland","child_ids":[],"parent_id":null},{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6136171004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5196267004,"location":{"name":"London"},"metadata":null,"id":6136171004,"updated_at":"2026-11-02T09:35:35-05:00","requisition_id":"457","title":"Security Engineer (Corporate Security), London","company_name":"Isomorphic Labs","first_published":"2026-08-06T11:42:16-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As a Security Engineer (Corporate Security)\u0026amp;nbsp;you will play a pivotal role in creating and maintaining a resilient, user-friendly and scalable corporate security environment at Isomorphic Labs. Operating with a proactive, service-minded approach and a strong bias for AI and automation, you will safeguard our workforce, identity systems, and sensitive data.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;In this unique and polyvalent role, you will implement and maintain pragmatic corporate security controls across a wide range of domains such as IAM, DLP, corporate/external applications, and data governance. You will participate in detection and incident response and develop long-lasting measures to improve our corporate security posture. Beyond technical controls, you will also build scalable and secure operational processes across a wide range of domains such as data transfer or systems integration that will materially impact IsoLabs’ mission. You will directly support AI/medical researchers on security topics and will ensure our cross-functional teams can innovate rapidly, securely, and with total confidence.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Corporate Identity \u0026amp;amp; Access Management (IAM): Design, optimize, and support corporate IAM structures, including group architectures, identity system integration, and streamlined employee onboarding/offboarding workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Corporate Security Controls: Audit corporate systems security and deploy/maintain a wide range of security tools (e.g., logging, monitoring \u0026amp;amp; DLP, data labeling, AI agents).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Data Governance: Collaborating with Corp Engineering, enhance data governance and security within corporate systems (Google Workspace, Confluence, Jira, Slack, etc.) by gathering user needs and co-developing scalable operating models, appropriate configurations, and SOPs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Incident Response \u0026amp;amp; Alert Triage: Partner closely with Detection \u0026amp;amp; Response security engineers to improve and triage corporate security alerts, support incident response efforts when issues arise and address Google’ vulnerabilities and bugs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Security Awareness: Promote corporate security rules, support security awareness training and run social engineering exercises.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Workplace Security: Collaborate with Workplace and Tech teams to ensure the security of physical systems (badges, lab workstations) and offices.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Security of Operations \u0026amp;amp; Processes: Translate key user needs and security compliance requirements into clear operational processes—such as establishing workflows for onboarding new tools, setting up data transfers and external system integrations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Third-Party Risk Management (TPRM): Execute standardized vendor and software audits, improve SaaS Security Posture Management (SSPM) through tools, and address third-party integrations and supply-chain safety risks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Automation \u0026amp;amp; AI Integration: Leverage AI tools and agentic workflows to automate routine security tasks, optimize triage, and streamline operations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;User Enablement: Act as a positive, proactive point of contact for internal teams, delivering user-oriented security solutions that reduce friction while upholding high security standards.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Fluency in navigating complex multi-org corporate systems’ workflows and processes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with Atlassian’s and/or Google’s tech stacks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in collecting user needs and business requirements, turning high-level guidance into efficient SOPs, policies, and guidelines documents.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong foundation in Corporate Systems Security and IAM, including hands-on experience with SSO, user lifecycle management, and directory/group structures.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in basic Python, Go, or PowerShell to interface with REST APIs across SaaS ecosystems (Slack, Google Workspace, Okta).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of SaaS Security Posture Management (SSPM), and ideally, experience using tools like AppOmni, Adaptive Shield, or native SaaS log analysis to spot misconfigurations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience implementing Data Loss Prevention (DLP) corporate controls, data classification/labeling, and corporate data governance frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Practical experience establishing or executing standardized vendor technical security assessments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Background in supporting security incident response and handling daily security alert triage.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A strong bias for automation and an eagerness to leverage AI tools or agentic scanning mechanisms within corporate security workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proactive, positive, and highly user-oriented mindset with exceptional communication skills to collaborate with technical and non-technical stakeholders alike.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience in high-growth tech environments, BioTech, ML-centric companies, or the pharmaceutical industry.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with OWASP Top 10 for LLMs, prompt injection prevention, and secure integration of internal AI assistants.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience building or integrating AI-driven automation, agentic workflows, or custom scripts for security operations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understanding of security patterns for Electronic Lab Notebooks (ELNs), Laboratory Information Management Systems (LIMS), or High-Performance Computing (HPC) environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with GitHub Enterprise security settings, secret scanning, and developer environment hardening.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with common data protection regulations and security frameworks (e.g., GDPR, ISO 27001).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Relevant industry certifications (e.g., Security+, CISSP, CISA, GSEC).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044354004,"name":"Tech","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6219237004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5226562004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6219237004,"updated_at":"2026-10-07T08:43:16-04:00","requisition_id":"497","title":"Senior Finance Business Partner (Clinical), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-10-07T08:43:16-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As our Senior Finance Business Partner (Clinical Development), you will serve as the dedicated financial strategic partner to our growing Clinical Development team. You will be a critical contributor to the success of this team and will be responsible for financial management of all clinical-related work.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a new role supporting our team based in Cambridge, MA. You will have the opportunity to bring financial thought leadership and rigor to key stakeholders as Iso progresses more medicines into the clinic as we march towards our mission to Solve All Disease.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About you\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Collaborative Partner:\u0026lt;/strong\u0026gt; Someone who builds trusting relationships, acts as a strategic thought partner and can bridge between science and finance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Proactive Problem Solver\u0026lt;/strong\u0026gt;: A curious, resourceful mindset with the drive to resolve issues pragmatically and optimise our playbook and processes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Detail and Process Oriented\u0026lt;/strong\u0026gt;: Highly organized and meticulous with clinical trial budgets. Capable of balancing multiple operational workflows whilst maintaining high standards.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Independent and Growth-Oriented\u0026lt;/strong\u0026gt;: A self-starter, always looking for ways to streamline processes and leverage technology to increase efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Business \u0026amp;amp; Financial Partnering: \u0026lt;/strong\u0026gt;Serve as the primary finance partner for the Clinical Development team. Provide strategic thought partnership to support delivery of clinical portfolio objectives.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Budgeting and Forecasting: \u0026lt;/strong\u0026gt;You will guide end-to-end clinical budgeting, forecasting, and resource planning. You will build and maintain bottoms-up financial models for clinical studies (e.g. tracking site activations, patient enrolment, pass-through costs etc)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Vendor Oversight \u0026amp;amp; Advisory: \u0026lt;/strong\u0026gt;Partner with Clinical Operations and Procurement during RFP processes to evaluate, benchmark, and negotiate budgets with clinical vendors. Support vendor onboarding, invoice review/approval, P2P processes and troubleshooting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Reporting \u0026amp;amp; Process Improvement: \u0026lt;/strong\u0026gt;Deliver regular variance analysis and continuously enhance financial reporting and workflows to support portfolio growth. Develop robust and efficient accruals processes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Cambridge Finance Lead: \u0026lt;/strong\u0026gt;As our first finance hire in Cambridge, MA, you will act as the Cambridge site finance lead and partner closely with the site leadership team.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Clinical Finance Expertise: \u0026lt;/strong\u0026gt;Direct experience managing clinical development finances (CROs, sites) and FP\u0026amp;amp;A/partnering within biotech, pharma, or life sciences. Deep experience in financial analysis including building and maintaining robust patient-driven financial models.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Education \u0026amp;amp; Analytical Skills: \u0026lt;/strong\u0026gt;Degree in Finance, Accounting, Economics, or other quantitative field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Communication \u0026amp;amp; Rigor: \u0026lt;/strong\u0026gt;Clear executive-level communicator for both technical and non-technical audiences. Strong attention to detail and ability to manage competing priorities in a fast-paced environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Teamwork and collaboration: \u0026lt;/strong\u0026gt;Proven track record in business partnering and excellence in stakeholder management.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;AI to drive efficiency: \u0026lt;/strong\u0026gt;Experience in utilizing LLMs and other AI to drive efficiency\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Professional accounting qualification (e.g., ACA, ACCA, CIMA, CPA, or equivalent).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience using Google Workspace (Sheets, Slides etc) .\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience managing financial systems (e.g. ERP, procurement).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044361004,"name":"Central  ","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6219244004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5226565004,"location":{"name":"London"},"metadata":null,"id":6219244004,"updated_at":"2026-10-07T08:43:44-04:00","requisition_id":"498","title":"Senior Finance Business Partner (Drug Design and Development), London, UK","company_name":"Isomorphic Labs","first_published":"2026-10-07T08:43:44-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As our Senior Finance Business Partner (Drug Design and Development), you will serve as the dedicated partner to our drug discovery organisation for both strategic and operational finance. You will be a critical contributor to the success of this team and will be responsible for financial management of all drug development-related work from discovery to preclinical testing.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a new role supporting our team based in London. You will have the opportunity to bring financial thought leadership and rigor to key stakeholders as Iso builds its drug portfolio and march towards its mission to Solve All Disease.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About you\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Collaborative Partner:\u0026lt;/strong\u0026gt; Someone who builds trusting relationships across all levels, acts as a strategic thought partner and bridges between science and finance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Proactive Problem Solver\u0026lt;/strong\u0026gt;: A curious, resourceful mindset with the drive to resolve issues proactively and pragmatically, and to optimise our playbook and processes for future success.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Detail and Process Oriented\u0026lt;/strong\u0026gt;: Highly organized and meticulous with budgets, forecasts, and reporting. Able to balance multiple workflows whilst maintaining high standards.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Independent and Growth-Oriented\u0026lt;/strong\u0026gt;: A self-starter, always looking for ways to streamline processes and leverage technology (particularly AI) to increase efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Business \u0026amp;amp; Financial Partnering: \u0026lt;/strong\u0026gt;Serve as the primary finance partner for the Drug Design and Development team. Provide strategic thought partnership to support delivery of portfolio objectives.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Budgeting and forecasting:\u0026lt;/strong\u0026gt; Lead end-to-end budgeting, forecasting, and resource planning.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Program and asset economics:\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Provide financial decision support for the Portfolio Steering Team. Build project-level NPV and risk-adjusted valuation models for pipeline assets to support portfolio prioritization.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with Business Development to model economics for biopharma partnerships and licensing deals, research collaborations and milestones.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Research Oversight \u0026amp;amp; Advisory: \u0026lt;/strong\u0026gt;Partner with our External Research team and Procurement during RFP processes to evaluate, benchmark, and negotiate budgets with vendors.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Reporting \u0026amp;amp; Process Improvement: \u0026lt;/strong\u0026gt;Deliver regular variance analysis and continuously enhance financial reporting and workflows to support portfolio growth. Oversee robust and efficient accruals processes.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Drug Development Finance Expertise: \u0026lt;/strong\u0026gt;Direct experience managing R\u0026amp;amp;D / drug development finance and FP\u0026amp;amp;A/partnering within biotech, pharma, or life sciences.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Finance modeling:\u0026lt;/strong\u0026gt; Deep experience building and maintaining robust financial models for portfolio prioritisation and project NPV.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Education \u0026amp;amp; Analytical Skills: \u0026lt;/strong\u0026gt;Degree in Finance, Accounting, Economics or other quantitative field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Communication \u0026amp;amp; Rigor: \u0026lt;/strong\u0026gt;Clear executive-level communicator for both technical and non-technical audiences. Strong attention to detail and ability to manage competing priorities in a fast-paced environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Teamwork and collaboration: \u0026lt;/strong\u0026gt;Proven track record in business partnering, influencing senior leadership, and excellence in stakeholder management.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;AI to drive efficiency: \u0026lt;/strong\u0026gt;Experience in utilizing LLMs and other AI to drive efficiency\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Professional accounting qualification (e.g., ACA, ACCA, CIMA, CPA, or equivalent).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Life sciences background/experience highly desirable\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience using Google Workspace (Sheets, Slides etc) .\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience implementing or managing financial systems (e.g. ERP, procurement).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044361004,"name":"Central  ","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6202766004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5221061004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6202766004,"updated_at":"2026-09-24T06:27:10-04:00","requisition_id":"485","title":"Senior Legal Counsel, Clinical  ","company_name":"Isomorphic Labs","first_published":"2026-09-24T06:27:10-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;As Senior Legal, Clinical, you will play a pivotal role in advancing our drug candidates into and through clinical development. Working as part of our global legal function, and embedded directly alongside our clinical operations and development teams in Cambridge, you will serve as the dedicated legal partner driving the drafting, negotiation and execution of high-volume, critical clinical research agreements. Your expertise will safeguard IsoLabs\u0026#39; intellectual property and regulatory posture, while accelerating clinical trial initiation, directly contributing to our mission of bringing AI-designed medicines to patients at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Draft, review, negotiate and execute a wide variety of clinical research agreements, including Clinical Trial Agreements (CTA), Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements.\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as the primary, day-to-day legal business partner embedded directly alongside the Clinical Development team.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with internal stakeholders to establish, scale and optimise standardised clinical contracting playbooks and template libraries to streamline study start-up timelines.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify, manage and mitigate legal, regulatory, intellectual property, data privacy, and compliance risks across global clinical operations.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate closely with cross-functional Legal \u0026amp;amp; Business Operations colleagues (IP, Corporate Legal and Privacy) to ensure end-to-end alignment on trial governance and data rights.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manage outside counsel and clinical transactions legal budget.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proactively evaluate, pilot, and embed cutting-edge AI technologies into the clinical contracting lifecycle to accelerate legal operations.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;J.D. or equivalent law degree with active U.S. state bar admission in good standing (Massachusetts Bar or eligible for in-house registration in MA).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Substantial, direct experience structuring, drafting, and negotiating complex clinical trial agreements, Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements.\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience gained either within a biotechnology/pharmaceutical in-house legal department or a specialised life sciences law firm practice.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expert knowledge of clinical trial execution, CRO outsourcing models and regulatory guidelines (GCP/ICH).\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to work autonomously and prioritise a high volume of transactions in a fast-paced, high-growth environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong collaborative mindset with exceptional stakeholder communication skills, tailored to embedding directly with scientific, medical and clinical operations teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with global and multi-jurisdictional clinical trial contracting landscapes (US, UK, and EU regulatory frameworks).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience navigating clinical data rights and IP provisions at the intersection of computational biology, data-intensive research, or AI-driven platforms.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044361004,"name":"Central  ","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6239325004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5234205004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6239325004,"updated_at":"2026-10-30T13:23:25-04:00","requisition_id":"510","title":"Senior Legal Counsel, Corporate Transactions, Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-10-30T12:25:16-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are hiring an exceptional, strategic, and results-driven Senior Legal Counsel, Corporate Transactions, to support and execute high-impact strategic transactions, including business development, corporate development, and other expanding deal pipelines. Reporting to the Head of Corporate Legal, you will play a key role in supporting transaction execution, scaling the legal function, and building our partnership network.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role directly addresses our increasing transaction volume and complexity across corporate, business, and strategic deal pipelines, including specialized research collaborations, co-development agreements, M\u0026amp;amp;A \u0026amp;amp; investment deals. By bringing experienced transaction execution in-house, you will accelerate deal velocity and support our evolving partnership strategy.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a core operational driver, you will scale our partnership strategy by establishing deal playbooks, standardizing term sheets, and building robust due diligence processes for corporate development and other strategic initiatives. You will also lead comprehensive risk mitigation across data licensing \u0026amp;amp; corporate structuring. Ultimately, this role reinforces partnering and IsoLegal\u0026#39;s contributions as essential investments to power Isomorphic Labs toward achieving its mission, directly aligning with and enabling our corporate priorities.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Partner closely with deal team stakeholders and cross-functional teams to structure, draft, negotiate, and close complex corporate, business development, corporate development, and strategic transaction deal pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manage various transactions across their lifecycle, handling specialized research collaborations, co-development partnerships and data licensing agreements from concept through execution and kick-off.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Play a leading role on all aspects of the transaction lifecycle from initial outreach through to final contract closing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive operational scaling within the IsoLegal function by developing standardized deal playbooks, template term sheets, and efficient due diligence workflows tailored to streamline corporate development and other strategic initiatives.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead legal due diligence efforts, mitigating corporate, data licensing, information security and technology transfer risks while ensuring regulatory and contractual compliance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Streamline deal execution through tech enablement to decrease reliance on external legal counsel, optimize legal expenditures, and empower deal teams with business-minded legal counsel.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as a key liaison to BD, scientific, and leadership stakeholders, aligning legal risk management directly with Iso\u0026#39;s strategic objectives and company goals.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Operate at the interface of various stakeholders including Business Development, Alliance Management, Legal and scientific and research teams to capture requirements for contract drafting.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;J.D. or equivalent legal qualification with significant corporate transactional experience within biotech, pharma, or life sciences technology sectors.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;5 years experience at a highly-rated law firm advising on transactions\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated success structuring and executing complex transactions, including research collaborations, co-development agreements \u0026lt;span style=\u0026quot;text-decoration: underline;\u0026quot;\u0026gt;and\u0026lt;/span\u0026gt; data licensing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven expertise in legal risk mitigation, particularly around data governanc \u0026lt;span style=\u0026quot;text-decoration: underline;\u0026quot;\u0026gt;and \u0026lt;/span\u0026gt;complex corporate structures.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience scaling legal operations, including building deal playbooks and standardizing term sheets and diligence processes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strategic thinker with proven experience in defining and executing long-term growth plans.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Significant understanding of the drug development lifecycle, from early-stage research through clinical development and commercialisation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to thrive in a fast-paced, entrepreneurial, and globally distributed environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;High level of personal integrity and dedication to fostering a collaborative culture.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with leveraging AI tools and legal technology to streamline day-to-day workflows, including contract review, drafting, and research.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Advanced degree (PhD or MS) or industry experience in life sciences.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working on buy-side M\u0026amp;amp;A transactions or corporate VC.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working in-house supporting business or corporate development teams.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044361004,"name":"Central  ","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6231897004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5231401004,"location":{"name":"London"},"metadata":null,"id":6231897004,"updated_at":"2026-10-23T05:42:59-04:00","requisition_id":"505","title":"Senior Research Investigator (Biologics Computational Science), London","company_name":"Isomorphic Labs","first_published":"2026-10-23T05:41:11-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your Impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We’re seeking a Senior Research Investigator to join our Computational Sciences team, specialising in Biologics. You will contribute to the design of novel large molecule therapeutics, harnessing the transformative power of our cutting-edge AI drug design engine. This role requires a unique blend of scientific expertise and the intellectual curiosity to explore uncharted territory in therapeutic design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You’ll play a pivotal role in our drug design projects, working with key internal and external stakeholders to drive the progress of complex projects in early discovery through to candidate selection and, ultimately, advancing candidates towards the clinic. This is an extraordinary opportunity to collaborate closely with Isomorphic Labs’ world-leading AI, ML, and drug discovery experts, developing imaginative new approaches, based on generative AI, to design and optimise protein-based therapeutics.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What You Will Do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Identify opportunities for computational modelling to enhance biologics discovery programs, including developing new methods.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with machine learning and biologics discovery teams to develop computational and machine learning methods for predicting biologics properties from sequence, including affinity, developability and immunogenicity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Apply computational methods to discover novel therapeutics.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Benchmark existing computational methods and develop baseline models.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyse data from lab experiments to inform decisions for biologics discovery programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Determine what data to generate to improve machine learning models. Implement model-aware prioritization to ensure we are collecting the highest-value data points, laying the foundations for active learning.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop methods for predicting functional properties of biologics, expressed in terms of biophysical constraints.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Skills and Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience using computational and machine learning methods to predict biologics properties.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience developing computational methods to predict biologics properties from sequence, such as affinity, developability or immunogenicity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;PhD or equivalent in computer science, computational biology, structural biology, biochemistry or related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficient programming skills with a strong emphasis on Python.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience preparing datasets, benchmarking models, and working with structure-based metrics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable learning new ways of working in fast changing environments\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to Have\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Industry experience in a pharma or biotech environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working in multidisciplinary large molecule drug discovery teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with structural modelling of biologics, including 3D protein structure tools.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience using generative-design methods for biologics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working with complex biologics modalities, such as antibody-drug conjugates (ADC’s) or multispecifics.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6232044004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5231455004,"location":{"name":"London"},"metadata":null,"id":6232044004,"updated_at":"2026-10-23T15:50:22-04:00","requisition_id":"506","title":"Senior Research Investigator, (Biologics Pharmacology), London","company_name":"Isomorphic Labs","first_published":"2026-10-23T15:50:22-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Your Impact\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We’re seeking a Senior Research Investigator specialising in biologics drug development to contribute to the pharmacology and translational biology strategy of our novel large molecule therapeutics, harnessing the transformative power of our cutting-edge AI drug design engine. This role requires a unique blend of scientific expertise and the intellectual curiosity to explore uncharted territory in therapeutic design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Within the Biologics Design and Research team, you will play a pivotal role in our drug discovery projects, working with key internal and external stakeholders to drive the pharmacology strategy of complex projects in early discovery through to candidate selection and, ultimately, advancing candidates towards the clinic. This is an extraordinary opportunity to collaborate closely with Isomorphic Labs’ world-leading AI, ML, and drug discovery experts, developing imaginative new approaches, based on generative AI, to design and optimise protein-based therapeutics.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;What You Will Do\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Translational Biology Strategy: \u0026lt;/strong\u0026gt;Design, execute, and oversee comprehensive pharmacology plans for our large molecule therapeutics.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;In Vivo \u0026amp;amp; In Vitro Evaluation: \u0026lt;/strong\u0026gt;Lead the design and execution of \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt; efficacy and complex \u0026lt;em\u0026gt;in vitro\u0026lt;/em\u0026gt; functional assays to ensure high-quality data generation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Drive Project Milestones:\u0026lt;/strong\u0026gt; Act as the Biology Lead for assigned projects, coordinating complex internal workflows and external CROs to efficiently progress candidates toward critical go/no-go decisions and program milestones.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;New Target Identification:\u0026lt;/strong\u0026gt; Collaborate with computational biology and design teams to identify, evaluate, and bring new biologics projects into the portfolio, assessing biological feasibility and therapeutic potential.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Collaborative Platform Building:\u0026lt;/strong\u0026gt; Partner closely with interdisciplinary teams (ML, Biology, CompBio) to help build our generative AI platform, ensuring the pharmacology data you generate is effectively fed back into design loops, while collaborating to deploy these cutting-edge tools to discover novel therapeutic strategies.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and Qualifications\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Immunology, Cancer Biology, Molecular Biology, Biochemistry, Pharmacology or a related scientific discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;5+ years’ professional experience in an industry role within a biotech or pharma setting.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A strong scientific expertise in, and in-depth understanding of, disease models and their use in biologics drug development. A strong interest in applying the latest technological advances to better predict translation to patients.\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Significant experience in the design and execution of studies to support project progression in the field of biologics drug discovery and development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience within the immunology, inflammation or oncology therapeutic areas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A proficiency with modalities such as multi-specifics or antibody drug conjugates (ADCs).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated proficiency in fostering and managing external collaborations with Contract Research Organizations (CROs) and world-leading academic groups.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A genuine passion and enthusiasm for applying AI/ML to drug design and how this can transform the field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication (written and verbal) and interpersonal skills, with a proven ability to work effectively in a cross-functional, collaborative team environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Track record of creative problem solving of some of the most difficult problems in drug discovery, with a strong growth mindset, adaptability, and eagerness to learn new concepts and techniques.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience leveraging machine learning or computational biology techniques for biologics design and optimisation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in antibody discovery, engineering, and optimisation strategies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;In-depth understanding of protein structure-function relationships of antibodies.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6233140004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5231782004,"location":{"name":"London"},"metadata":null,"id":6233140004,"updated_at":"2026-11-03T11:02:14-05:00","requisition_id":"507","title":"Senior Research Investigator / Research Leader  (Translational Pharmacology), London","company_name":"Isomorphic Labs","first_published":"2026-11-03T09:45:58-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are seeking an accomplished and visionary translational biologist to join our Translational Pharmacology team in London, working at the forefront of multidisciplinary, AI-first drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;In this role, you will shape and advance our exploratory research portfolio, with an initial core focus on neurodegenerative diseases as well as adjacent high unmet need indications. Operating at the interface of disease biology, translational science, and AI-driven molecular design, you will translate deep mechanistic insights of human disease into robust therapeutic hypotheses, target validation packages, and decision-critical experimental workflows to progress programs from target identification to portfolio entry.\u0026lt;br\u0026gt;\u0026lt;br\u0026gt;Working shoulder-to-shoulder with world-leading machine learning researchers, computational biologists, and drug designers, you will bridge the gap between dry-lab predictive models and experimental biology—ensuring our AI platforms are grounded in disease-relevant biology and guiding next-generation medicines towards clinical reality.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026amp;nbsp;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Therapeutic Area Strategy \u0026amp;amp; Target Discovery:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Partner with therapeutic area leadership to define and evolve our neurodegeneration research strategy, identifying priority indications, emerging biological mechanisms, and high-value therapeutic opportunities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate insights across human genetics, disease pathology, clinical datasets, and advanced cellular models to critically evaluate target tractability, translational relevance, and competitive differentiation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive early portfolio progression decisions by establishing rigorous go/no-go target validation criteria.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Translational Biology \u0026amp;amp; Experimental Execution:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop human disease-relevant therapeutic hypotheses that connect target modulation directly to clinically meaningful outcomes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Translate therapeutic concepts and target product profiles (TPPs) into biologically rigorous screening cascades for internal and partnered programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Profile novel chemical matter emerging from our in silico generative design pipelines, building comprehensive pre-clinical data packages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Embed early translational thinking around target engagement indicators, translational biomarkers, and patient stratification strategies.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Cross-Functional Collaboration with AI/ML Teams:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Work closely with AI/ML, computational biology, and structural biology teams to design assays and experimental systems that meaningfully benchmark and evaluate AI-designed molecules.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide critical biological domain expertise to ML teams to guide and inform generative models of biological systems and disease pathways.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Scientific Leadership \u0026amp;amp; External Partnerships:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Serve as the scientific lead for portfolio programs, directing scientific strategy, managing timelines, and ensuring the delivery of decision-quality data.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design, oversee, and manage outsourced studies with external Contract Research Organisations (CROs) and academic/co-development collaborators.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain strong awareness of global scientific advances, competitive clinical landscapes, and emerging translational technologies in neurodegeneration and diseases of aging.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;br\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h4\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h4\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD or equivalent industrial/research experience in Neuroscience, Translational Medicine, Pharmacology, Cellular/Molecular Biology, or a related discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep mechanistic understanding of neurodegenerative disease biology, including cellular and molecular drivers of pathology in complex, high-unmet-need indications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expert practical knowledge of translational models (\u0026lt;em\u0026gt;in vitro\u0026lt;/em\u0026gt;, \u0026lt;em\u0026gt;ex vivo\u0026lt;/em\u0026gt;, and \u0026lt;em\u0026gt;in vivo\u0026lt;/em\u0026gt;), patient-derived cellular systems, and the design of robust screening cascades from Target ID through Hit-to-Lead/Lead Optimisation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated success in advancing therapeutic hypotheses through target validation and profiling novel chemical matter to build decision-quality data packages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven experience designing, contracting, and managing external research studies with CROs and academic collaborators.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience collaborating closely with bioinformatics, cheminformatics, or computational biology teams, utilising data-driven approaches for target discovery and compound progression.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Highly collaborative, agile, and driven to thrive in a high-velocity, interdisciplinary team environment.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Track record of driving strategic compound de-risking and SAR in close collaboration with medicinal chemistry and DMPK teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of biophysical, biochemical, and cellular screening techniques (e.g., SPR, TR-FRET, mass spectrometry, high-content imaging) and how machine learning models interact with these assay outputs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Broad biological experience in diseases of aging or neuroinflammation outside classical neurodegeneration.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior experience in early clinical biomarker discovery or target engagement assay development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/5990644004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5151784004,"location":{"name":"London"},"metadata":null,"id":5990644004,"updated_at":"2026-10-07T11:37:53-04:00","requisition_id":"404","title":"Senior Technical Program Manager (InfoSec), London","company_name":"Isomorphic Labs","first_published":"2026-05-07T11:54:54-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As InfoSec Technical Program Manager, you will translate Isolabs’ security strategy into engineering reality. Reporting to the CISO, with a strong functional tie to the TPM Discipline Lead, you will operate at the critical intersection of risk management and research velocity. You will steer the InfoSec Roadmap, driving complex security initiatives—from protecting proprietary AI models to embedding Zero Trust architecture—across a fast-moving, highly regulated landscape.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Going beyond traditional project management, you are a technical enabler who partners directly with engineering and ML teams. You will navigate architectural roadblocks, secure sensitive drug discovery pipelines, and ensure leadership has the data-driven, operational visibility needed to protect a pioneer in digital biology.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Structure and drive multi-quarter security project roadmap, balancing long-term strategic initiatives (e.g., Cloud Security, Platform IAM, Secure SDLC) with immediate business needs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead ad-hoc initiatives and high-priority business requests, such as securing sensitive regulated data transfers for drug discovery to architecting guardrails for novel Agentic AI workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive the end-to-end delivery of security projects by working hand-in-hand with engineers, navigating the complex Alphabet/Google Ecosystem, and ensuring high-quality execution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Educate and advocate for InfoSec across the business, acting as a “product manager” regarding InfoSec’s capabilities, assets, responsibilities, and SLAs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build extensive and trusting relationships with engineers, researchers and leaders across the company. Act as the bridge between the business and security in order to provide balanced recommendations to the CISO and the TPM Lead.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design automated, data-driven dashboards that provide the CISO and engineering leaders with clear visibility into program health, operational KPIs, and risk reduction metrics.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Technical Credibility: Deep fluency across Security, Tech, and AI, allowing you to partner effectively with senior engineers and researchers.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strategic Execution: Proven track record of driving complex roadmaps from concept to delivery. You excel at navigating ambiguity and taking decisive action when scientific and financial stakes are high.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Pragmatic Risk Management: Ability to make calculated trade-offs between security posture, technical debt, and research velocity without stalling innovation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Cross-Functional Influence: Exceptional ability to influence without formal authority, championing security as a core priority across engineering, ML, and business teams.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proactive Problem Solving: You anticipate architectural bottlenecks, untangle cross-team dependencies, and turn complex organisational friction into clear, actionable project plans.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Translational Communication: Highly skilled at translating CISO’s objectives into technical requirements and condensing complex technical and organisational challenges into concise and actionable plans for leadership.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Domain expertise in highly regulated, data-intensive industries (Life Sciences, Pharma, Deep Tech).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience navigating GCP and the internal Alphabet/Google ecosystem (on-corp)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Engineering background with hands-on skill regarding Cloud Architecture, Zero Trust, IAM, and security observability.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with\u0026amp;nbsp; InfoSec and AI Management Frameworks (ISO 27001, ISO 42001) and emerging AI security frameworks (e.g., OWASP Top 10 for LLMs, MITRE ATLAS).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Industry-standard security or program management certifications (e.g., CISSP, CISM, CCSP, or Agile/Scrum methodologies).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044354004,"name":"Tech","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/5837899004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5069005004,"location":{"name":"London"},"metadata":null,"id":5837899004,"updated_at":"2026-09-23T03:55:30-04:00","requisition_id":"388","title":"Staff Software Engineer (Inference Platform), London","company_name":"Isomorphic Labs","first_published":"2026-03-26T06:46:11-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Your Impact\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are building the largest foundation models in biotech and applying them immediately to cure disease. You will play a pivotal role in ensuring the reliability and scalability of the foundations that make this possible.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a Principal Engineer, you will lead the efforts to harden our systems, ensuring our groundbreaking AI is built on an unshakeable base, working closely with the research team and the Applied ML teams to ensure the infrastructure is stable, reliable and can operate with more data and larger models as we grow.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;What You Will Do\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop and operate our inference platform, serving fleets of cutting-edge machine learning models to scientific applications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design strategy and build roadmaps for maturing the platform.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Architect and optimize our next-generation inference services. You will solve core scaling limits, ensuring high-throughput performance and feature parity across our model serving stack.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to core technical decisions on tooling and architectural design while partnering with science, product, and operations teams to align infrastructure with biotech R\u0026amp;amp;D cycles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deliver high-quality and well-tested user-focused features.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Skills and Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Proven experience in architecting and managing large-scale AI/ML workloads in a production environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Orchestration: Significant experience deploying and managing complex workloads within Kubernetes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in cloud compute design, specifically within Google Cloud Platform (GCP).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Professional familiarity with NVIDIA GPU generations and the intricacies of high-performance compute.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong programming skills and a \u0026quot;reliability-first\u0026quot; approach to software development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Nice to Have:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;A career history that spans both ML Software Engineering and Infrastructure SRE roles.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience leading multi-disciplinary projects and navigating complex stakeholder requirements in a fast-paced environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with workload scheduling, ML efficiency research, and hardware benchmarking.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with Google TPU generations and specialized ML-driven R\u0026amp;amp;D cycles.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044354004,"name":"Tech","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6180357004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5210591004,"location":{"name":"London"},"metadata":null,"id":6180357004,"updated_at":"2026-10-23T11:38:05-04:00","requisition_id":"477","title":"Team Coordinator, President Team, London","company_name":"Isomorphic Labs","first_published":"2026-09-04T12:07:45-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are looking for an energetic, highly reliable and proactive Team Coordinator to join the President Team. Reporting directly to the President’s Executive Assistant, you will be the essential \u0026quot;boots on the ground\u0026quot; force ensuring the day-to-day physical operations, guest experiences and events of the executive suite run flawlessly.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is an execution-focused, highly collaborative role for a true \u0026quot;do-er\u0026quot; who thrives on detail, mucks in wherever needed and takes pride in being a warm, professional extension of Isomorphic Labs’ President Team.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Executive Support \u0026amp;amp; Meeting Readiness\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Own the end-to-end physical preparation for executive meetings, including printing and binding high-stakes materials, ensuring tech is connected, and preparing meeting spaces to immaculate standards to ensure pristine room and tech readiness.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Own the physical logistics, environmental readiness and material distribution for all of the President’s internal speaking engagements and events, including company-wide forums, fireside chats and leadership presentations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Act as the face of the President’s team by greeting high-profile external guests, facilitating their arrival experience, and providing flawless hospitality (making coffees, teas, and setting up refreshments) with a high-touch, warm presentation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Take charge of local, practical details around the office and event venues—knowing the best pickup/drop-off points, tracking traffic or courier delays, and handling the local neighborhood logistics so everything runs without friction.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Handle real-time adjustments on the President\u0026#39;s travel days, coordinating directly with drivers or transport providers to ensure arrivals, departures, and transitions are perfectly timed and seamless.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Run day-to-day administrative errands, including picking up executive lunches, organising couriers, and handling urgent operational requests while remaining highly proactive, responsive, and dynamic to real-time on-the-ground changes and issues that arise.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish great working relationships and closely liaise with internal stakeholders, alongside external workplace teams, to ensure seamless suite operations.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Team Operations \u0026amp;amp; Stakeholder Engagement\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Coordinate and deliver the end-to-end operational and space logistics for key leadership meetings, internal team milestones, and stakeholder events.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Help bring team culture to life by driving the sourcing, logistics, and delivery of internal recognition projects and milestone keepsakes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support the external operations of the President\u0026#39;s Office by handling the physical distribution, courier logistics, and preparation of outward-facing materials with high attention to detail.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Event \u0026amp;amp; Offsite Support\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Travel to select offsites and external leadership events to oversee physical space setup and ensure room layouts match the agenda\u0026#39;s requirements while providing proactive, on-the-ground reactive logistics support to dynamically handle real-time shifts.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Act as the primary on-the-ground point of contact for external coaches and facilitators, ensuring they have all physical materials, tech, and space requirements fully sorted.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;You possess a high bias for action. No task is too small, and you genuinely enjoy \u0026quot;mucking in\u0026quot; to solve problems before others even notice them, showing deep responsiveness to the unexpected.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You understand that small things matter—whether it\u0026#39;s the alignment of a printed document, the creative presentation of a gift, or the temperature of a meeting room.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be operating around sensitive information and high-profile guests; you bring a calm, polished, warm, approachable, and strictly confidential presence to the workplace.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You can switch gears instantly when schedules shift and maintain an upbeat, solution-oriented attitude under pressure.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You can track multiple moving parts—from vendor deliveries for custom gifts to organizing presentation materials for global events and offsites—while actively liaising with external workplace stakeholders.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Reporting Structure \u0026amp;amp; Growth\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role offers a unique window into high-level executive operations. You will report directly to the Executive Assistant to the President, sitting within a tight-knit support ecosystem that flows up into the President\u0026#39;s Senior Operating Partner.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044361004,"name":"Central  ","child_ids":[],"parent_id":null}],"offices":[{"id":4026429004,"name":"London ","location":"London, England, United Kingdom","child_ids":[],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null},{"absolute_url":"https://job-boards.greenhouse.io/isomorphiclabs/jobs/6220158004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":5227036004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6220158004,"updated_at":"2026-11-02T05:57:14-05:00","requisition_id":"499","title":"Technical Program Manager (Drug Discovery), Cambridge, MA","company_name":"Isomorphic Labs","first_published":"2026-10-09T10:13:18-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;About Iso\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Your impact\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;As part of the ongoing expansion of our Drug Design and Medical Research (DDMR) function, we are looking to recruit our first Technical Program Manager to our Cambridge, MA office.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a member of the Technical Program Management team you will be responsible for facilitating all aspects of small molecule drug discovery program management for Cambridge programs, providing hands-on support to our AI-first Drug Design programs, ensuring smooth integration with our London office. You will work in alignment with the drug design teams in Cambridge and liaise with key internal stakeholders across finance, legal, alliance management and AI/tech.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you are an organised, skilled and ambitious individual looking to take the next step in your career, joining Isomorphic Labs now will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;What you will do\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;As a member of the TPM team you will be responsible for supporting DDMR with program planning, dynamically monitoring timelines, action tracking, risk reporting, driving effective meetings and stakeholder management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will manage and monitor program budgets with respect to forecasting and actual spend to support the program team, DDMR and TPM team as well as report out to senior stakeholders\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will provide help to program teams to effectively liaise with CROs and other external providers/partners, helping with contract reviews and processing\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will help to build and embed processes and operating systems, ensuring integration and alignment across Isolabs\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;Skills and qualifications\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;h5\u0026gt;\u0026lt;span style=\u0026quot;font-size: 12pt;\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/h5\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At least a BSc in Biology, Chemistry or related discipline\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven industry experience in contributing to, managing or leading early stage / discovery small molecule and / or glue and / or peptide drug design programs\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understanding of small molecule / glue / peptide drug discovery \u0026amp;amp; development processes in the context of project \u0026amp;amp; program planning, and governance\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of managing budgets, including planning, forecasting, monitoring, troubleshooting and working to identify efficiencies\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of operational program management processes\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with program risk management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience supporting teams in fast-paced and constantly changing environments\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to adaptively interact and confidently communicate with diverse key stakeholders\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Patient, organised and detail-oriented\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;span style=\u0026quot;font-size: 12pt;\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Nice to have:\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Advanced degree in Biology, Chemistry or related discipline\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Program management qualification\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience of working in an ML drug discovery environment\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working with Jira and / or confluence or other program management software\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Culture and values\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We are guided by our shared values. It\u0026#39;s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Thoughtful\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Brave\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Determined\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Together\u0026lt;br\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400;\u0026quot;\u0026gt;Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Creating an extraordinary company\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;We believe that to be successful we need a team with a range of skills and talents. We\u0026#39;re building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;br\u0026gt;Hybrid working\u0026lt;/strong\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and \u0026lt;strong\u0026gt;would require you to be able to come into the office 3 days a week\u0026lt;/strong\u0026gt; (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Please note that when you submit an application, your data will be processed in line with our \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;privacy policy\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;br\u0026gt;\u0026amp;gt;\u0026amp;gt; \u0026lt;a href=\u0026quot;https://www.isomorphiclabs.com/work-with-us#current-job-openings\u0026quot;\u0026gt;Click to view other open roles at Isomorphic Labs\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4044357004,"name":"DDMR","child_ids":[],"parent_id":null}],"offices":[{"id":4061239004,"name":"Cambridge, MA","location":"Cambridge, Massachusetts, United States","child_ids":[4061240004],"parent_id":null}],"ai_disclaimer":null,"include_ai_disclaimer":null,"ai_opt_out_request_url":null}],"meta":{"total":34}}