{"jobs":[{"absolute_url":"https://job-boards.greenhouse.io/discmedicine/jobs/5074900008","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":4405777008,"location":{"name":"Massachusetts - Hybrid"},"metadata":null,"id":5074900008,"updated_at":"2026-06-01T10:35:05-04:00","requisition_id":"2026016","title":"Associate Director, Analytical Development \u0026 Clinical Quality Control","company_name":"Disc Medicine","first_published":"2026-05-14T16:11:51-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.\u0026amp;nbsp; \u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;COMPANY OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;POSITION OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Associate Director of Quality Control will manage quality activities for biologics programs in clinical development, ensuring compliance with ICH and GMP guidelines. The primary functions include method validation and method transfers to and from CDMOs. Additionally, this role will lead and or participate in specification setting activities for early and late-stage biologics programs as well as manage method life cycle. Significant contributions from this role will be essential for facilitating regulatory filings of Disc Medicine assets.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position reports to the Director of Analytical Development and Clinical Quality Control within the Technical Operations organization at Disc Medicine. The ideal candidate should have 10-12 years of experience in quality control management in the pharmaceutical or biotech industry.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;RESPONSIBILITIES:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role will have extensive technical expertise and be responsible for method validation and method transfer for Disc Medicine’s clinical development programs. The technical responsibilities include:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Author, review, and approve method transfer protocols and reports from transferring and receiving CDMOs per regulatory requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author, review, and approve method validation protocols and reports from transferring and receiving CDMOs per regulatory requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author, revise, and approve governing SOPs, protocols, reports and memos in accordance with current GMP, ICH, and global regulatory guidelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead or participate in specification setting activities for early and late-stage biologics programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manage method lifecycle, including periodic reviews to assess method performance\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manage Quality System records for QC activities: author, assess, review Deviations, Change Controls, CAPAs, and other applicable quality-related investigations and events\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support GMP audits and inspections.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Act as the team leader to ensure alignment and effective communication among cross-functional areas, including analytical development, process development, formulation development, manufacturing, supply chain, regulatory, quality assurance, and other internal and external partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and improve processes to ensure compliance with global regulatory requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish and maintain a network of external partners to fulfill technical and capacity requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support the budget planning and resource allocation to support laboratory operations and staffing.\u0026lt;strong\u0026gt;\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;REQUIREMENTS:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;A B.S. degree is required; an advanced degree (e.g., M.S./Ph.D.) in a related field is preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;At least 10-12 years of experience in the biopharmaceutical industry, including prior leadership experience in quality control functions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with a track record of method validation, method transfer, and hands-on management of day-to-day testing operations for outsourced biologics therapeutics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of statistics and statistical tools (GraphPad Prism, JMP) to assist in trending and or specification setting\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of Quality processes such as change control, CAPAs, and deviations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience and knowledge with Root Cause Analysis tools for OOS investigations is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience conducting QC OOS investigations and write-ups in conjunction with CDMOs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with Veeva, LIMS and Smartsheet desirable.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of bioanalytical and analytical methods, including but not limited to LC-MS, GC-MS, UV-vis, IR/FT-IR, HPLC (SEC, icIEF), CE-SDS, ELISA, cell-based potency assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of quality systems, global regulatory requirements (example: 21 CRF Part 11/210/211,820), and Guidance documents.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of technical writing for CMC sections of regulatory documents (IND, MAAs)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exceptional organizational, interpersonal, and communication skills, both verbal and written, with the ability to facilitate meetings, conduct training, and to present information in an advisory capacity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Attention to detail, excellent review skills, and the ability to organize and manage multiple tasks in a fast-paced environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Able to travel up to 25%.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to work both independently and collaboratively with project teams and cross-functionally, to build productive relationships with internal and external partners, to influence decision-making, and to engage in conflict resolution.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The annual base salary range for this position is listed below. Actual pay rates are determined by considering multiple factors including qualifications, relevance of experience, education \u0026amp;amp; credentials, subject matter expertise, and internal parity.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Salary Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$158,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$193,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit their resume to be considered for current and future opportunities.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine respects your privacy.\u0026amp;nbsp; For information about how Disc processes your personal data in the context of your candidacy, please see our\u0026amp;nbsp;\u0026lt;a href=\u0026quot;https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.discmedicine.com%2Fwp-content%2Fuploads%2F2025%2F06%2FPrivacyNotice_Final.pdf\u0026amp;amp;data=05%7C02%7Cedomann%40discmedicine.com%7Cd1d721d1a5eb43f683f108de4ed273ff%7C6deedf28ffbe4ca88c8985f256117dc6%7C1%7C0%7C639034862964186947%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C\u0026amp;amp;sdata=rVgNWYR6Rq2ayA3M1wMMAXbW3%2FDFE1SYvsXsfsvYmII%3D\u0026amp;amp;reserved=0\u0026quot;\u0026gt;Privacy Notice\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4006075008,"name":"302 - Analytical Development and Clinical QC","child_ids":[],"parent_id":4006060008}],"offices":[{"id":4005299008,"name":"United States","location":"Massachusetts, United States","child_ids":[4005307008,4005313008,4005314008,4005315008,4005308008,4005318008,4005309008,4005310008,4005306008,4005316008,4005317008,4005311008,4005312008,4034635008,4034636008,4034637008],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/discmedicine/jobs/5077926008","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":4407160008,"location":{"name":"Massachusetts - Hybrid"},"metadata":null,"id":5077926008,"updated_at":"2026-05-18T09:28:21-04:00","requisition_id":"2026017","title":"Associate Director, Drug Product","company_name":"Disc Medicine","first_published":"2026-05-18T09:28:21-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.\u0026amp;nbsp; \u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;COMPANY OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;POSITION OVERVIEW\u0026lt;/strong\u0026gt;\u0026lt;strong\u0026gt;:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Reporting to Executive Director, Biologics Drug Product; the Principal Scientist / Associate Director in Biologics Drug Product Development will be responsible for providing leadership for drug product technical elements of assets within the biologics pipeline programs, focusing on antibodies and/or proteins. The technical elements of this role may be responsible encompass biologics formulation development, drug product process development, technology transfer and manufacturing support, as well as development of subcutaneous delivery devices. This role will also be expected to contribute to authoring early and late-stage clinical filings as well as commercial filings. This position requires significant hands-on industry experience in the biologics formulation and drug product process development and manufacturing support areas, with a focus on antibodies and proteins.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;RESPONSIBILITIES:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Provide leadership to multiple technical elements of drug product development for Disc Medicine’s biologic drug product programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead selected clinical and/or commercial formulation studies for antibody and/or biologics programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead drug product process development and characterization activities for selected unit operations supporting early and/or late-stage clinical programs up to and including process performance qualification batches (PPQ).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;If necessary, participate in selecting and recommending appropriate external providers (CMOs/CROs), to support formulation and fill/finish process development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide significant technical leadership to drug product process transfers to CMOs as well as oversee drug product formulation, process development, and manufacturing at contract development and manufacturing organizations (CDMO)s.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide expertise across various areas of biologics drug product development, such as in-use compatibility, extractables/leachables, and filter validation studies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;As necessary, contribute to device selection, design control, and/or validation activities for subcutaneous delivery systems, such as pre-filled syringes, needle safety devices, and/or autoinjectors.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Form effective relationships and collaborate well with the CMC leader(s) and CMC functions, including drug substance, analytical development, quality control, supply chain, and quality and regulatory organizations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contributed to the budget management of assigned programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Engage with CMC and/or Executive Leadership, as appropriate, to proactively identify and communicate technical risks and provide scientific recommendations for mitigation plans.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to a positive workplace culture that prioritizes collaboration, ensures accountability, and a commitment to continuous improvement.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026amp;nbsp;REQUIREMENTS:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;A BS/MS in Chemical Engineering, Pharmaceutical Sciences, or similar areas is required.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;10-15 years in the pharmaceutical / biopharmaceutical industry with a minimum of 4-6 years of hands-on experience with early and/or late-stage drug product development programs, such as formulation, process, and/or device development and technology transfer.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledgeable in sterile drug product development, technology transfer, and manufacturing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in formulation development of antibody products through various stages of the product lifecycle, including first in human through to commercial formulations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in contributing to the authoring drug product sections of early and late-stage clinical filings, as well as commercial filings, is highly preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong ability to communicate well with cross-functional groups, including Drug Substance, Analytical Development, Quality, Regulatory, and Program Management.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Significant experience working within CMC teams and with CMC team leaders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior experience working with domestic and international CDMOs for development and GMP manufacturing activities, including person in plant support.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to contribute to high-performing teams, including exceptional communication as well as fostering cross-functional teamwork.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent collaboration and interpersonal skills with ability to convey complex ideas succinctly.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Travel of 20-30% may be required.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The annual base salary range for this position is listed below. Actual pay rates are determined by considering multiple factors including qualifications, relevance of experience, education \u0026amp;amp; credentials, subject matter expertise, and internal parity.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Salary Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$167,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$205,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit their resume to be considered for current and future opportunities.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine respects your privacy.\u0026amp;nbsp; For information about how Disc processes your personal data in the context of your candidacy, please see our\u0026amp;nbsp;\u0026lt;a href=\u0026quot;https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.discmedicine.com%2Fwp-content%2Fuploads%2F2025%2F06%2FPrivacyNotice_Final.pdf\u0026amp;amp;data=05%7C02%7Cedomann%40discmedicine.com%7Cd1d721d1a5eb43f683f108de4ed273ff%7C6deedf28ffbe4ca88c8985f256117dc6%7C1%7C0%7C639034862964186947%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C\u0026amp;amp;sdata=rVgNWYR6Rq2ayA3M1wMMAXbW3%2FDFE1SYvsXsfsvYmII%3D\u0026amp;amp;reserved=0\u0026quot;\u0026gt;Privacy Notice\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4068263008,"name":"306 - Biologics DP Mfg.","child_ids":[],"parent_id":4006060008}],"offices":[{"id":4005299008,"name":"United States","location":"Massachusetts, United States","child_ids":[4005307008,4005313008,4005314008,4005315008,4005308008,4005318008,4005309008,4005310008,4005306008,4005316008,4005317008,4005311008,4005312008,4034635008,4034636008,4034637008],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/discmedicine/jobs/5077955008","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":4407173008,"location":{"name":"Massachusetts - Hybrid"},"metadata":null,"id":5077955008,"updated_at":"2026-05-13T14:35:21-04:00","requisition_id":"2026018","title":"Director, Clinical Quality Control","company_name":"Disc Medicine","first_published":"2026-05-07T09:37:41-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.\u0026amp;nbsp; \u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;COMPANY OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;POSITION OVERVIEW\u0026lt;/strong\u0026gt;\u0026lt;strong\u0026gt;:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As Disc Medicine transitions from a clinical-stage organization to a commercial-stage one, the company is introducing a new role: Director of Clinical Quality Control. The successful candidate will play a crucial role in driving the company’s growth and achieving strategic objectives.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Director of Quality Control will manage stability studies for various small-molecule and biologics programs in clinical development, ensuring compliance with ICH and GMP guidelines. The primary functions include protocol design; coordination and execution of various stability studies at CDMOs; statistical analysis; and expiration dating.\u0026amp;nbsp; Additionally, this role will oversee the end-to-end supply of reference standards for quality control testing, including sourcing/production, qualification, inventory and distribution, as well as lifecycle monitoring. Significant contributions from this role will be essential for facilitating regulatory filings of Disc Medicine assets.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position reports to the Head of Analytical Development and Clinical Quality Control within the Technical Operations organization at Disc Medicine. The ideal candidate should have at least 10 years of experience in quality control management in the pharmaceutical or biotech industry.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;RESPONSIBILITIES:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role will have extensive technical expertise and be responsible for stability and reference standard management for Disc Medicine’s clinical development programs. The technical responsibilities include:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Evaluate, select, and manage CDMOs for QC stability testing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Direct stability studies per ICH guidance, sample pulls, and data analysis to determine retest periods and product shelf-life.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Create, revise, and approve SOPs, stability protocols, and reports in accordance with current GMP, ICH, and global regulatory guidelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Create, implement, and manage stability databases, forecast stability testing, and report on metrics, perform data trending and statistical analysis to support expiry dating.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manage Quality System records for QC Stability: create, assess, review Deviations, Change Controls, CAPAs, and other applicable stability-related investigations and events\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee the sourcing, characterization, qualification, retesting, and inventory management of primary and working reference standards.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author and review the stability and reference standard sessions of the global health authority dossier for clinical trials and commercial licensure.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support GMP audits and inspections.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Act as the team leader to ensure alignment and effective communication among cross-functional areas, including analytical development, process development, formulation development, manufacturing, supply chain, regulatory, quality assurance, and other internal and external partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and improve processes to ensure compliance with global regulatory requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish and maintain a network of external partners to fulfill technical and capacity requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support the budget planning and resource allocation to support laboratory operations and staffing.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026amp;nbsp;REQUIREMENTS:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;A B.S. degree is required; an advanced degree (e.g., M.S./Ph.D.) in a related field is preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;At least 12-15 years of experience in the biopharmaceutical industry, including prior leadership experience in quality control functions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of product stability, setting of specifications, product shelf-life management, and experience with QC OOS investigations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of data management tools and statistical process control, and data integrity requirements and expectations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with Veeva, LIMS and Smartsheet desirable.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of bioanalytical and analytical methods, including but not limited to LC-MS, GC-MS, UV-vis, IR/FT-IR, HPLC (SEC, icIEF), CE-SDS, ELISA, cell-based potency assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with method validation, method transfer, and hands-on management of day-to-day testing operations for outsourced small molecules and biologics therapeutics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of quality systems, global regulatory requirements (example: 21 CRF Part 11/210/211,820), and Guidance documents.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of technical writing for CMC sections of regulatory documents (IND, MAAs)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exceptional organizational, interpersonal, and communication skills, both verbal and written, with the ability to facilitate meetings, conduct training, and to present information in an advisory capacity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Attention to detail, excellent review skills, and the ability to organize and manage multiple tasks in a fast-paced environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Able to travel up to 25%.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to work both independently and collaboratively with project teams and cross-functionally, to build productive relationships with internal and external partners, to influence decision-making, and to engage in conflict resolution.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The annual base salary range for this position is listed below. Actual pay rates are determined by considering multiple factors including qualifications, relevance of experience, education \u0026amp;amp; credentials, subject matter expertise, and internal parity.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Salary Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$198,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$242,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit their resume to be considered for current and future opportunities.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine respects your privacy.\u0026amp;nbsp; For information about how Disc processes your personal data in the context of your candidacy, please see our\u0026amp;nbsp;\u0026lt;a href=\u0026quot;https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.discmedicine.com%2Fwp-content%2Fuploads%2F2025%2F06%2FPrivacyNotice_Final.pdf\u0026amp;amp;data=05%7C02%7Cedomann%40discmedicine.com%7Cd1d721d1a5eb43f683f108de4ed273ff%7C6deedf28ffbe4ca88c8985f256117dc6%7C1%7C0%7C639034862964186947%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C\u0026amp;amp;sdata=rVgNWYR6Rq2ayA3M1wMMAXbW3%2FDFE1SYvsXsfsvYmII%3D\u0026amp;amp;reserved=0\u0026quot;\u0026gt;Privacy Notice\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4006075008,"name":"302 - Analytical Development and Clinical QC","child_ids":[],"parent_id":4006060008}],"offices":[{"id":4005299008,"name":"United States","location":"Massachusetts, United States","child_ids":[4005307008,4005313008,4005314008,4005315008,4005308008,4005318008,4005309008,4005310008,4005306008,4005316008,4005317008,4005311008,4005312008,4034635008,4034636008,4034637008],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/discmedicine/jobs/5074028008","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":null,"location":{"name":"United States"},"metadata":null,"id":5074028008,"updated_at":"2026-01-16T11:38:26-05:00","requisition_id":null,"title":"Join Our Talent Community","company_name":"Disc Medicine","first_published":"2026-01-16T11:31:03-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.\u0026amp;nbsp; \u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;COMPANY OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;JOIN OUR TALENT COMMUNITY\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Not seeing a position that matches your interests?\u0026amp;nbsp; Not ready to Apply?\u0026amp;nbsp; No problem. Stay connected with us by joining our Talent Community.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;By signing up, you\u0026#39;ll receive updates on career opportunities and company news tailored to your professional interests. Whether you\u0026#39;re exploring future roles or simply want to stay informed, our Talent Community keeps you updated.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As we continue to advance our clinical pipeline and progress towards commercialization, we\u0026#39;re eager to connect with driven professionals ready to make an impact. Whether your background is in R\u0026amp;amp;D, Tech Ops, Commercial, Medical Affairs, or General \u0026amp;amp; Administrative, we invite you to connect with us today.\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit their resume to be considered for current and future opportunities.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine respects your privacy.\u0026amp;nbsp; For information about how Disc processes your personal data in the context of your candidacy, please see our\u0026amp;nbsp;\u0026lt;a href=\u0026quot;https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.discmedicine.com%2Fwp-content%2Fuploads%2F2025%2F06%2FPrivacyNotice_Final.pdf\u0026amp;amp;data=05%7C02%7Cedomann%40discmedicine.com%7Cd1d721d1a5eb43f683f108de4ed273ff%7C6deedf28ffbe4ca88c8985f256117dc6%7C1%7C0%7C639034862964186947%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C\u0026amp;amp;sdata=rVgNWYR6Rq2ayA3M1wMMAXbW3%2FDFE1SYvsXsfsvYmII%3D\u0026amp;amp;reserved=0\u0026quot;\u0026gt;Privacy Notice\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[],"offices":[]},{"absolute_url":"https://job-boards.greenhouse.io/discmedicine/jobs/5238098008","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":4483323008,"location":{"name":"Remote in WA, OR, CA"},"metadata":null,"id":5238098008,"updated_at":"2026-06-03T16:56:16-04:00","requisition_id":"2026040","title":"Medical Science Liaison, Associate - West Coast","company_name":"Disc Medicine","first_published":"2026-06-02T10:46:49-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.\u0026amp;nbsp; \u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;COMPANY OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;POSITION OVERVIEW\u0026lt;/strong\u0026gt;\u0026lt;strong\u0026gt;:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is searching for a Medical Science Liaison (MSL) that will strategically support the medical objectives of Disc Medicine’s clinical development programs. This role will be responsible for identifying, developing, and maintaining strong relationships with Key Opinion Leaders (KOLs) and a network of healthcare professionals (HCPs), engaging in peer-to-peer conversations and providing scientific and clinical expertise.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;RESPONSIBILITIES:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Identify, develop and maintain strong relationships with KOLs, academic institutions, community centers, and HCPs in relevant areas of focus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Engage in meaningful peer-to-peer exchanges with the appropriate therapeutic area community (e.g., hematologists, dermatologists, hepatologists, rare disease community).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as a scientific expert and resource, providing accurate support to internal and external stakeholders and timely information about Disc’ clinical data, ongoing research and programs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide internal stakeholders with feedback and actionable insights from interactions and discussions with KOLs and HCPs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assist with company-sponsored trials, investigator-initiated trials (IITs) or research collaborations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deliver scientific presentations and trainings to internal and external stakeholders\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assist with organizing regional advisory boards as applicable, and presenting at advisory board meetings within your territory.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build a trustful and collaborative working relationship with cross-functional colleagues.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Focus on delivering results and demonstrate ownership in key medical projects.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Adhere to all relevant compliance and regulatory guidelines, ensuring all activities are conducted ethically and within legal boundaries.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026amp;nbsp;REQUIREMENTS:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Advanced Clinical/Science degree or professional credentials required (PhD, MD, PharmD, MSc)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;5–8 years of industry experience as a Medical Science Liaison (MSL) or in a similar role, including required experience in dermatology; hematology experience strongly preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication and presentation skills and the ability to effectively communicate complex scientific concepts to diverse audiences\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to work cross-functionally and communicate effectively with a variety of internal / external stakeholders and across senior management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Must be intellectually curious, professional, and adaptable\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Willingness to travel extensively to engage with KOLs, HCPs, and attend scientific conferences\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong analytical skills, especially understanding and interpreting scientific and clinical research and literature\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in Microsoft Office programs and CRMs is required.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The annual base salary range for this position is listed below. Actual pay rates are determined by considering multiple factors including qualifications, relevance of experience, education \u0026amp;amp; credentials, subject matter expertise, and internal parity.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Salary Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$185,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$230,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit their resume to be considered for current and future opportunities.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine respects your privacy.\u0026amp;nbsp; For information about how Disc processes your personal data in the context of your candidacy, please see our\u0026amp;nbsp;\u0026lt;a href=\u0026quot;https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.discmedicine.com%2Fwp-content%2Fuploads%2F2025%2F06%2FPrivacyNotice_Final.pdf\u0026amp;amp;data=05%7C02%7Cedomann%40discmedicine.com%7Cd1d721d1a5eb43f683f108de4ed273ff%7C6deedf28ffbe4ca88c8985f256117dc6%7C1%7C0%7C639034862964186947%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C\u0026amp;amp;sdata=rVgNWYR6Rq2ayA3M1wMMAXbW3%2FDFE1SYvsXsfsvYmII%3D\u0026amp;amp;reserved=0\u0026quot;\u0026gt;Privacy Notice\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4006083008,"name":"405 - Medical Affairs and Patient Advocacy","child_ids":[],"parent_id":4006060008}],"offices":[{"id":4005299008,"name":"United States","location":"Massachusetts, United States","child_ids":[4005307008,4005313008,4005314008,4005315008,4005308008,4005318008,4005309008,4005310008,4005306008,4005316008,4005317008,4005311008,4005312008,4034635008,4034636008,4034637008],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/discmedicine/jobs/5235423008","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":4482066008,"location":{"name":"Massachusetts - Hybrid"},"metadata":null,"id":5235423008,"updated_at":"2026-06-01T08:41:21-04:00","requisition_id":"2026039","title":"Principal Scientist/Associate Director, Analytical Development \u0026 Clinical Quality Control","company_name":"Disc Medicine","first_published":"2026-06-01T08:41:21-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.\u0026amp;nbsp; \u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;COMPANY OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;POSITION OVERVIEW\u0026lt;/strong\u0026gt;\u0026lt;strong\u0026gt;:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Reporting to a Director of Analytical Development/Clinical QC, this position requires expert knowledge of the biopharmaceutical drug development process in late-stage development, with working knowledge and experience in method development, transfer of analytical methods, and management of external vendors. This individual will contribute to late-stage analytical development strategy and content of regulatory filings. Excellent communication skills, attention to detail, and organizational skills are essential for this role.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;RESPONSIBILITIES:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Characterize biologic therapeutics using standard analytical extended techniques to explore relationships between structure and function. These techniques include but are not limited: chromatographic techniques (CEX, SEC, HILIC, etc.), mass spectrometry-based techniques including peptide mapping (LC/MS) and intact mass, capillary electrophoresis, differential scanning calorimetry (DSC) or fluorimetry (DSF), glycosylation content measurement, ELISA, and potency assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee development of standard protein analysis methods through external vendors and guide transfer analytical methods to separate analytical and QC testing facilities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop analytical techniques to measure product and process impurities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strengthen relationships with external CDMO partners to establish and manage appropriate scopes of work, and to ensure all activities are within program expectations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide oversight into external testing facilities for non-GMP and GMP testing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead method performance investigations, troubleshooting, and laboratory investigations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working and up-to-date knowledge of ICH guidelines and other regulatory guidance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author, review and edit SOPs, protocols, reports, and quality related documentation for internal and external stakeholders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide authorship and review for regulatory documents for multiple countries.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate cross-functionally across multi-disciplinary teams including Analytical Development, Process Development, Drug Product Development, Regulatory, Quality Assurance, Supply Chain, and others.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026amp;nbsp;REQUIREMENTS:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelors degree is required. An advanced degree (M.S./Ph.D.) is preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;10-12+ years of related experience in the biopharmaceutical industry experience, with 2+ years in late-stage development of antibody or related therapeutics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with multiple analytical methods and specification development; troubleshooting experience with analytical methods using external vendors\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Good knowledge of cGMP and global regulatory requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop relationships and collaborate well with cross-functional groups, including Process Development, Manufacturing, Quality, and Regulatory.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Self-starter with demonstrated ability to deliver high-quality results in a fast-paced development environment. Ability to effectively prioritize and deliver on tight timelines while remaining flexible in a changing environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication and interpersonal skills; ability to convey complex ideas succinctly.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in IND and BLA filings is highly desired.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to travel occasionally\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The annual base salary range for this position is listed below. Actual pay rates are determined by considering multiple factors including qualifications, relevance of experience, education \u0026amp;amp; credentials, subject matter expertise, and internal parity.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Salary Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$158,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$193,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit their resume to be considered for current and future opportunities.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine respects your privacy.\u0026amp;nbsp; For information about how Disc processes your personal data in the context of your candidacy, please see our\u0026amp;nbsp;\u0026lt;a href=\u0026quot;https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.discmedicine.com%2Fwp-content%2Fuploads%2F2025%2F06%2FPrivacyNotice_Final.pdf\u0026amp;amp;data=05%7C02%7Cedomann%40discmedicine.com%7Cd1d721d1a5eb43f683f108de4ed273ff%7C6deedf28ffbe4ca88c8985f256117dc6%7C1%7C0%7C639034862964186947%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C\u0026amp;amp;sdata=rVgNWYR6Rq2ayA3M1wMMAXbW3%2FDFE1SYvsXsfsvYmII%3D\u0026amp;amp;reserved=0\u0026quot;\u0026gt;Privacy Notice\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4006075008,"name":"302 - Analytical Development and Clinical QC","child_ids":[],"parent_id":4006060008}],"offices":[{"id":4005299008,"name":"United States","location":"Massachusetts, United States","child_ids":[4005307008,4005313008,4005314008,4005315008,4005308008,4005318008,4005309008,4005310008,4005306008,4005316008,4005317008,4005311008,4005312008,4034635008,4034636008,4034637008],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/discmedicine/jobs/5152328008","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"education":"education_required","internal_job_id":4442869008,"location":{"name":"Massachusetts - Hybrid"},"metadata":null,"id":5152328008,"updated_at":"2026-03-25T16:40:10-04:00","requisition_id":"2026034","title":"Principal Scientist/Associate Director, DMPK","company_name":"Disc Medicine","first_published":"2026-03-16T09:50:50-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.\u0026amp;nbsp; \u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;COMPANY OVERVIEW:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;POSITION OVERVIEW\u0026lt;/strong\u0026gt;\u0026lt;strong\u0026gt;:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine’s Drug Metabolism and Pharmacokinetics (DMPK) team is seeking an experienced scientist to support the application of pharmacokinetic (PK) and pharmacodynamic (PD) sciences in our drug discovery and development portfolios, with more focus on biologics programs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a key member of the cross‑functional teams, you will apply in vitro, in vivo, and modeling approaches to characterize the absorption, distribution, metabolism, excretion (ADME), and PK/PD properties of small molecules and biologics.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will serve as a DMPK project representative and contribute across all stages of portfolio advancement, from early compound screening and optimization through IND‑enabling studies and regulatory submissions. Responsibilities include experimental design, data analysis and interpretation, human PK and efficacious dose projection, reporting, and strategic guidance.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role requires regular interaction with internal and external partners to ensure timely, high‑quality delivery of ADME/PKPD data and to drive DMPK strategy for both Discovery and Development programs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;RESPONSIBILITIES:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Serve as the DMPK representative on biologics and/or small molecule project teams, providing scientific and strategic leadership.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design, conduct, interpret, and report in vitro ADME, in vivo PK, and PK/PD studies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and maintain compound selection criteria to support consistent decision‑making across projects.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner effectively with modeling and simulation experts, toxicologists, and clinical pharmacologists for human PKPD prediction, toxicology and clinical study support.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Summarize and present scientific results to project teams, leadership, and broader stakeholders.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee external CRO partners to ensure high‑quality data generation within budget and timelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute expert‑level guidance to regulatory submissions for biologics and/or small molecules.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026amp;nbsp;REQUIREMENTS:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;MS in DMPK, biology, chemistry, or related field with 8+ years of relevant experience, or PhD (or equivalent) with 5+ years of relevant industry experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated expertise in large‑molecule PK, PKPD, and general discovery or development areas.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong working knowledge of ADME, PK, PKPD for small molecules is an important plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to evaluate and apply innovative PK and PK/PD approaches to predict human PK, generate hypotheses, design studies, inform clinical plans, and support regulatory filings is highly preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working effectively and collaboratively with cross‑disciplinary teams; ability to lead, influence, and contribute to decision‑\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent written and verbal communication skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;The annual base salary range for this position is listed below. Actual pay rates are determined by considering multiple factors including qualifications, relevance of experience, education \u0026amp;amp; credentials, subject matter expertise, and internal parity.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Salary Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$184,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$224,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit their resume to be considered for current and future opportunities.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Disc Medicine respects your privacy.\u0026amp;nbsp; For information about how Disc processes your personal data in the context of your candidacy, please see our\u0026amp;nbsp;\u0026lt;a href=\u0026quot;https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.discmedicine.com%2Fwp-content%2Fuploads%2F2025%2F06%2FPrivacyNotice_Final.pdf\u0026amp;amp;data=05%7C02%7Cedomann%40discmedicine.com%7Cd1d721d1a5eb43f683f108de4ed273ff%7C6deedf28ffbe4ca88c8985f256117dc6%7C1%7C0%7C639034862964186947%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C\u0026amp;amp;sdata=rVgNWYR6Rq2ayA3M1wMMAXbW3%2FDFE1SYvsXsfsvYmII%3D\u0026amp;amp;reserved=0\u0026quot;\u0026gt;Privacy Notice\u0026lt;/a\u0026gt;.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4006061008,"name":"201 - EDCP","child_ids":[],"parent_id":4006060008}],"offices":[{"id":4005299008,"name":"United States","location":"Massachusetts, United States","child_ids":[4005307008,4005313008,4005314008,4005315008,4005308008,4005318008,4005309008,4005310008,4005306008,4005316008,4005317008,4005311008,4005312008,4034635008,4034636008,4034637008],"parent_id":null}]}],"meta":{"total":7}}