{"jobs":[{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7922812","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3436760,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Science Programs","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You’ll develop data analysis workflows for spatiotemporal and multi-omics datasets.You will build visualization tools that enable exploration and interpretation of complex biological data across space and time.","value_type":"long_text"}],"id":7922812,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1685","title":"Computational Biologist","company_name":"Biohub","first_published":"2026-05-19T19:04:03-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our Vision\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;We pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;We enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;br\u0026gt;Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(0, 0, 0); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Biohub Chicago is seeking an exceptional Computational Biologist, Spatiotemporal Multi-Omics \u0026amp;nbsp;to join our growing team. We are looking for a creative and collaborative bioinformatics researcher who is excited to build the analytical foundation for our spatiotemporal multi-omics technology platform.\u0026lt;br\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop data analysis workflows for spatiotemporal and multi-omics datasets.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build visualization tools that enable exploration and interpretation of complex biological data across space and time.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate proteomics, metabolomics, and related datasets, and explore machine learning or transfer learning approaches to support biological discovery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate closely with experimental scientists, communicate findings clearly, and contribute to publications, presentations, and open-source software as appropriate.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering or a related quantitative discipline.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Minimum 2 years of experience in developing bioinformatic methods, analysis pipelines, or software tools for biological data using appropriate programming language.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Minimum of 1 year of experience in at least one of the following areas: spatial data analysis, multi-omics integration, or machine learning for biological applications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A strong record of research productivity, including publications, open-source contributions, or both.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A collaborative mindset, strong communication skills, and enthusiasm for working closely with wet-lab teams.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;(Preferred)\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;1+ year of experience with imaging mass spec (e.g., MALDI)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;1+ year of experience with single-cell proteomics and/or metabolomics\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;1+ year of experience building visualization tools, or scientific software.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Chicago, IL\u0026amp;nbsp; base pay range for a new hire in this role is $130,000 - $163,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;\u0026amp;nbsp;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7712408","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3373718,"location":{"name":"San Francisco, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub San Francisco"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will help lead image analysis for our next-generation Optical Pooled Screening program.","value_type":"long_text"}],"id":7712408,"updated_at":"2026-06-05T19:01:33-04:00","requisition_id":"R1620","title":"Computational Biologist II, CellxState","company_name":"Biohub","first_published":"2026-03-12T13:28:15-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Through our multi-dimensional imaging program, we build imaging tools that capture life across scales — from single proteins to whole organisms — revealing how proteins and cells function, communicate, and assemble into living systems. These observations are laying the groundwork for a new generation of AI models that can predict cellular behavior and guide the development of better treatments for widespread diseases. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/imaging/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our work brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Part of the Imaging Grand Challenge, The CELLxSTATE Program builds next-generation technologies to decode and control how cells make decisions — combining live-cell imaging, multi-omics, and AI at unprecedented scale.\u0026amp;nbsp; We also create large reference datasets that can be mined and reused by the entire community for discovery, like our OpenCell project that maps protein localization and interactions (\u0026lt;a href=\u0026quot;https://opencell.czbiohub.org/\u0026quot;\u0026gt;https://opencell.czbiohub.org/\u0026lt;/a\u0026gt;). Our science is fully open-source and published in journals like Science, Nature Methods, and Cell (\u0026lt;a href=\u0026quot;https://biohub.org/leonetti/publications/\u0026quot;\u0026gt;https://biohub.org/leonetti/publications/\u0026lt;/a\u0026gt;).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;At the core of our current efforts is multiDPS (Multimodal Dynamic Pooled Screening), a high-throughput platform that integrates custom microscopy, automation, CRISPR screening and molecular profiling to map and predict dynamic cell states.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a \u0026lt;strong\u0026gt;Computational Biologist \u0026lt;/strong\u0026gt;to help lead image analysis for our next-generation Optical Pooled Screening program. This is a great opportunity for candidates with a strong interest in data science, engineering, and cell biology, supported by experts in a highly collaborative and well-funded scientific environment. We embrace team science and our projects bring together biologists, technology developers, engineers, data scientists, and AI/ML experts.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design, develop, and maintain scalable image analysis pipelines for large-scale fluorescent microscopy datasets, with an emphasis on image quality robustness and computational efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate emerging multi-modal data types (e.g., spatial transcriptomics) into unified, AI-ready datasets that support downstream modeling and discovery.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Advance our bio-image analysis capabilities (e.g., segmentation, tracking, image-stitching, and image registration).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner closely with biologists and automation engineers to implement end-to-end quality control metrics, ensuring the fidelity of our experimental and computational pipelines.\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Architect modular and reusable processing frameworks that can flexibly support multiple experiment types within a shared infrastructure.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Publish and disseminate impactful findings through preprints, papers, and software repositories (e.g., GitHub).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Computational Biology, Biology, or Computer Science, or a MS with relevant job experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;At least 4 years of experience in Python-based image analysis or scientific computing. Experience with fluorescence microscopy, confocal, or lightsheet is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Fluency with computational tools and infrastructure such as Python, Github, and Slurm.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with modern biological data formats such as OME-Zarr and AnnData.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience designing workflows for large, complex datasets, including scalable storage formats, and reliable metadata and experiment tracking.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A proven track record of individual innovation, together with a strong ability to work collaboratively.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A passion for research and understanding how cells work.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;An enthusiasm for team science and open science - this position will be embedded in a large multi-disciplinary team.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent written and oral communication skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The San Francisco, CA base pay range for a new hire in this role is $153,000 - $210,100. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":58664,"name":"Chan Zuckerberg Initiative","location":"Redwood City, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7286341","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3260235,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will work at the intersection of foundation models, reasoning systems, and experimental immunology — developing frameworks for how these tools can be integrated into experimental workflows.","value_type":"long_text"}],"id":7286341,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1481","title":"Computational Biologist, Immune Perturbation","company_name":"Biohub","first_published":"2025-09-30T19:09:25-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/inflammation/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub is seeking a Computational Biologist to join our interdisciplinary AI/ML team within the Virtual Immune System initiative. This is a hands-on research role focused on building and evaluating lab-in-the-loop experimental systems and closing the cycle between computational models of immune cell behavior and wet-lab validation. The ideal candidate brings strong biological intuition, computational rigor, and experience applying machine learning to genomics or perturbation biology.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will work at the intersection of foundation models, reasoning systems, and experimental immunology — developing frameworks for how these tools can be integrated into experimental workflows. This means defining what questions are addressable, designing experiments that stress-test model predictions, guiding analysis, and evaluating performance across the loop. The environment is highly collaborative and interdisciplinary, spanning immunology, automation engineering, and machine learning, with direct applications to human health and disease.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design computationally-guided experiments leveraging reasoning models, foundation models, and automated lab infrastructure to address open questions in immunology and inflammation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with experimental scientists, automation engineers, and AI/ML researchers to define addressable biological questions, close the loop between model predictions and wet-lab validation, and iterate on experimental strategy.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and document best practices for designing experimental workflows, including data acquisition strategy, analysis pipelines, and frameworks for iterative refinement across the loop.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Critically evaluate model predictions by stress-testing outputs against external datasets, known biology, and expert intuition — identifying failure modes and feeding improvements back into model development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to publications, open-source tools, and translational applications that advance the field of computationally driven immune system modeling.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Immunology, Computer Science/Statistics, Computational Biology/Genomics, or a related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;3 to 5 years of experience of applying machine learning and computational approaches to biological problems, particularly in genomics or genetic perturbation screening (e.g., CRISPR-based screens, Perturb-seq).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with foundation models, LLMs, or reasoning models and a drive to rigorously evaluate where they do and don\u0026#39;t work when applied to biological questions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong biological intuition and a clear scientific point of view — able to identify which questions are tractable, design experiments that test model predictions, and know when results don\u0026#39;t pass the smell test.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong programming and data skills (Python preferred), with an emphasis on reproducibility and clear documentation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Effective cross-domain communicator with experience working alongside experimentalists, engineers, or other non-computational collaborators to translate between domains and validate computational predictions.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;The Chicago, IL base pay range for a new hire in this role is $162,000.00 - $202,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif; font-size: 12pt;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: rgb(126, 140, 141); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":305998,"name":"Platform","child_ids":[],"parent_id":305996}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7286324","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3260226,"location":{"name":"New York, NY (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["Science"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"Biohub NY seeks to recruit an outstanding scientist to serve as Group Leader (equivalent to a Principal Investigator in academia), leading our Immune Cell Reprogramming research program.\n\nThe Group Leader will build, lead, and oversee a small research team focused on elucidating immune cell mechanisms in disease at the cellular and molecular levels, with the ultimate goal of developing novel immunotherapies. The program should include a strong research emphasis on T cell exhaustion, including strategies to understand, prevent, and/or reverse this process.","value_type":"long_text"}],"id":7286324,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1467","title":"Group Leader, Immune Cell Reprogramming","company_name":"Biohub","first_published":"2026-04-23T16:57:49-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/immune-cell-reprogramming/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub NY seeks to recruit an outstanding scientist to serve as\u0026amp;nbsp;\u0026lt;strong\u0026gt;Group Leader \u0026lt;/strong\u0026gt;(equivalent to a Principal Investigator in academia), leading our Immune Cell Reprogramming research program.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Group Leader will build, lead, and oversee a small research team focused on elucidating immune cell mechanisms in disease at the cellular and molecular levels, with the ultimate goal of developing novel immunotherapies. The program should include a strong research emphasis on T cell exhaustion, including strategies to understand, prevent, and/or reverse this process.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The successful candidate will join a vibrant, deeply interdisciplinary community of scientists working at the intersection of immunology, cell engineering, and translational medicine—representing one of the largest and most collaborative ecosystems of its kind.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Ideal candidates will demonstrate a strong track record of scientific achievement, along with a commitment to collaboration in a highly interdisciplinary environment.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(51, 2, 156);\u0026quot;\u0026gt;Applicants are required to provide a \u0026lt;strong\u0026gt;cover letter\u0026lt;/strong\u0026gt; and a \u0026lt;strong\u0026gt;3-page\u0026lt;/strong\u0026gt;\u0026amp;nbsp;\u0026lt;strong\u0026gt;research statement.\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Identify, recruit, manage and mentor cell reprogramming lab members working under his/her supervision.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead and actively participate in an innovative, vigorous, and collaborative research program aligned with the mission of Biohub NY with the goal of elucidating the molecular and cellular mechanisms underlying cellular changes in chronic infection, cancer, or aging.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Play a collaborative role in our collective efforts to bioengineer immune cells for the detection and prevention of diseased states both within the Biohub NY and across the ecosystem of Biohubs and CZI activities.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrating outstanding productivity based on a compelling record of scientific publication, collaboration, and IP generation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Play a collaborative role in our collective efforts to elucidate critical immune cell mechanisms governing tissue residency and detection of aberrant cell states, with the aim of detecting and preventing diseased states.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop a transformative research vision and providing technical guidance and mentorship to team members.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Engage with colleagues throughout the Biohub and Biohubs ecosystem to uphold our values of scholarly excellence, innovation, open communication, hands-on collaboration, partnership, and research opportunities.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Clearly communicate progress and results to colleagues and to the leadership team.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Publish and disseminate impactful findings and the products of your research as preprints (medRxiv, bioRxiv) and/or software repositories (e.g., GitHub) and embrace the OpenScience policy of the Biohub.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with the\u0026amp;nbsp; Biohub team to patent and license technologies resulting from your research.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD or MD with relevant research experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;An exceptional publication record demonstrating both the candidate’s creativity and productivity\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A minimum of 3 years post-doctoral experience or clinical training\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated leadership, track record of innovation, and ability to work collaboratively.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Supervisory or mentoring experience is a plus but not required for early-career applicants, but expected for more senior candidates.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A creative vision to carry out or continue an innovative and impactful research program.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Outstanding interpersonal and communication skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The New York City, NY base pay range for a new hire in this role is $153,000.00 - $185,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Life of Service Gifts are awarded to employees to “live the mission” and support the causes closest to them.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid #LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287573,"name":"CZ Biohub NY, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7535647","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3336746,"location":{"name":"New York, NY (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["Science"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will aim to uncover the core principles and dynamic behaviors that govern immune system function in both health and disease.","value_type":"long_text"}],"id":7535647,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1595","title":"Group Leader, Immunology ","company_name":"Biohub","first_published":"2026-02-11T16:17:19-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;p\u0026gt;Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/immune-cell-reprogramming/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026lt;/p\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Biohub invites exceptional scientists to apply for a\u0026amp;nbsp;\u0026lt;strong\u0026gt;Group Leader \u0026lt;/strong\u0026gt;(Principal Investigator-equivalent) position. We seek researchers who pursue fundamental questions in immunology, including—though not limited to—experts in systems immunology, immune engineering, and functional or molecular immunology, with a particular emphasis on cellular subtypes associated with immune regulation in cancer and/or neuroinflammation. Ideal candidates will aim to uncover the core principles and dynamic behaviors that govern immune system function in both health and disease. We especially welcome applicants who integrate quantitative, high-throughput, and systems approaches to address broad immunological questions and principles, rather than those focused primarily on tool or method development. The overarching mission is to reveal the fundamental principles governing the function and development of the human immune system, including via regulatory, signaling, and cell-cell molecular interaction network analysis. The goal will be to identify mechanisms that can help reprogram the immune system’s function to monitor organ specific health conditions, modulate cell trafficking, and restore normal immune function in human disease conditions.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Biohub in New York fosters a vibrant environment where fundamental discovery and cross-disciplinary collaboration are encouraged. We particularly welcome scientists eager to collaborate across biology, computation, and engineering to generate transformative insights into immune biology. The successful candidate will join a highly collaborative environment of both intramural investigators at the Biohub network and extramural investigators at our partner institutes, Columbia University, Yale University and The Rockefeller University. The successful candidate will have access to world-class resources within the Biohub and across partner campuses. Candidates are expected to establish an independent, creative and innovative research program, as well as demonstrate a commitment to collaboration. The Biohub will offer a competitive package with full funding for research personnel, lab operational costs, and essential equipment.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Applicants must hold a Ph.D., M.D., or equivalent degree in immunology or a related field, and have a strong foundation in quantitative or mechanistic approaches to biological research. Applicants should have a record of at least five years of postdoctoral or equivalent research experience demonstrating creativity, independence, and impactful contributions in research aligned with the themes described above.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(51, 2, 156);\u0026quot;\u0026gt;Applicants are required to provide a \u0026lt;strong\u0026gt;cover letter\u0026lt;/strong\u0026gt; and a \u0026lt;strong\u0026gt;3-page\u0026lt;/strong\u0026gt;\u0026amp;nbsp;\u0026lt;strong\u0026gt;research statement.\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead an innovative, rigorous, and highly collaborative research program aligned with the mission of Biohub, focused on advancing fundamental understanding of the immune system.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop a transformative research vision and provide technical guidance and mentorship to team members.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Play a key role in our collaborative efforts to engineer immune cells to detect, prevent, and cure organ-specific diseased states by leveraging your expertise in immunology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Engage with colleagues throughout the Biohub to uphold our values of scholarly excellence, innovation, open communication, collaboration, partnership, and opportunity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Communicate progress and results with colleagues and the leadership team.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Publish and disseminate impactful findings and the products of your research as preprints (medRxiv, bioRxiv) and/or software repositories (e.g., GitHub).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with the Biohub team to patent and license technologies resulting from your research.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD or MD or equivalent degree in immunology or a related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A minimum of 5 years post-doctoral experience with a strong foundation in immunology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;An innovative research plan aimed at revealing the fundamental principles that govern the immune system.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated publication track record in top tier journals on topics related to the scientific goals of this position.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated leadership, track record of innovation, and ability to work collaboratively.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Supervisory or mentoring experience is a plus but not required for early-career applicants, but expected for more senior candidates.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrating a creative vision to establish a highly innovative and impactful research program.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Outstanding interpersonal and communication skills.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated commitment to open science and highly aligned with the mission and values of Biohub.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The New York City, NY base pay range for a new hire in this role is $153,000.00 - $185,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(51, 2, 156);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;em\u0026gt;Interviews will begin starting April 15th 2026 and will continue until the position has been filled.\u0026lt;/em\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287573,"name":"CZ Biohub NY, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7685480","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3375788,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Engineering","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["Science"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will lead a world-class team of passionate engineers building transformative tools at the intersection of AI and biology. Your work will power the next generation of products that accelerate the analysis and interpretation of complex biological data using cutting-edge foundation models.","value_type":"long_text"}],"id":7685480,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1621","title":"Head of Engineering, AI Products","company_name":"Biohub","first_published":"2026-03-05T20:24:37-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;p\u0026gt;Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The AI Products team builds software products that transform AI models and biological data into scalable applications that accelerate scientific discovery. Working closely with AI model developers, researchers, and biologists, we connect the dots between research and scientific impact.\u0026lt;/p\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p data-start=\u0026quot;408\u0026quot; data-end=\u0026quot;679\u0026quot;\u0026gt;As the Head of Engineering for the AI Products group, you would lead a team of highly motivated and talented software engineers to build tools and products that accelerate the processing and interpretation of biological data and cutting-edge foundation models in biology.\u0026lt;/p\u0026gt;\n\u0026lt;p data-start=\u0026quot;681\u0026quot; data-end=\u0026quot;1197\u0026quot;\u0026gt;The team will tackle ambitious technical challenges — running model inference at scale; interpreting and visualizing multi-dimensional, high-resolution images and videos of cells; and processing and visualizing protein datasets containing over 1 billion proteins. Working closely with Product Managers, Product Designers, and Product Marketers, the team’s work will power the next generation of products that accelerate the analysis and interpretation of complex biological data using cutting-edge foundation models.\u0026lt;/p\u0026gt;\n\u0026lt;p data-start=\u0026quot;1199\u0026quot; data-end=\u0026quot;1354\u0026quot;\u0026gt;This is an opportunity to shape the future of AI-driven biology while leading a team that turns breakthrough research into impactful, real-world solutions.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Lead an engineering team focused on building reliable, scalable, extensible software products.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work cross-functionally with internal and external partners to develop and deliver on the roadmap, and to shape the long-term strategy for how AI Products drive our scientific impact ambitions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Participate in and encourage Agile software development practices to deliver frequent value to our users and enable continuous feedback loops.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Set the technical direction, guide the team’s technical decisions, and ensure that best practices are consistently followed.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure high quality in the work we deliver and serve as a hands-on manager to the team.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide mentorship and career development support to direct reports.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hire and onboard engineers to fill resource gaps while building out a diverse team.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;8+ years of experience in Software Engineering, including 4+ years of engineering leadership as a people manager.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track of building and delivering high-impact products on top of AI models in complex, data-driven domains.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep technical expertise with the ability to translate complex theory into practical, scalable solutions—driving research, rigorous analysis, clear conclusions, and decisive execution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Extensive experience hiring, managing, and developing high-performing engineering teams while cultivating a culture of excellence, ownership, and impact.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong cross-functional collaborator, partnering with interdisciplinary stakeholders to define product strategy, shape requirements, and deliver robust software solutions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Influential and empathetic leader who provides clear, direct guidance, inspires collaboration, and consistently coaches engineers to accelerate their technical growth and career progression.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Active contributor to architectural strategy and technical design decisions, elevating engineering standards and long-term system quality.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The future anticipated Redwood City, CA base pay range for a role in this field is\u0026amp;nbsp;$241,000–$338,000 annually. Compensation ranges will vary based on job-related skills, level of experience, and knowledge. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;br\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347396,"name":"AI Products","child_ids":[],"parent_id":39963}],"offices":[{"id":287577,"name":"Redwood Shores","location":null,"child_ids":[],"parent_id":287574}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7747522","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3397435,"location":{"name":"New York, NY (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Artificial Intelligence","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will have the opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science.","value_type":"long_text"}],"id":7747522,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1643","title":"Machine Learning Engineer, AI","company_name":"Biohub","first_published":"2026-04-08T00:30:09-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world\u0026#39;s leading biologists. We\u0026#39;re not a startup trying to find product-market fit, and we\u0026#39;re not a pharma company optimizing a pipeline. We\u0026#39;re building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our research spans:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Imaging foundation models trained across the world\u0026#39;s largest microscopy datasets\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Reasoning and agentic systems that connect frontier LLMs with biological foundation models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Join our Team!\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As an ML Engineer, you\u0026#39;ll join some of the strongest infrastructure engineers in AI, building the systems that connect everything together. The infrastructure problems you solve directly determine what science becomes possible.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Work with high-dimensional scientific data formats and contribute to backend compatibility, format evaluation, and I/O performance benchmarking at petabyte scale.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define and shape the engineering patterns your team and collaborating researchers will build on for years; the abstractions you write today become the foundation others depend on at scale.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work at the intersection of AI systems and biological discovery, where the infrastructure problems you solve directly determine what science becomes possible.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deploy models to production and manage artifact tracking across models and datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and optimize GPU-native data loading pipelines for large-scale multi-dimensional tensor workloads, including profiling and resolving hardware utilization bottlenecks across multi-backend systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work on simplification and improvement of codebase abstractions to accelerate research momentum.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build and maintain primitives for pre-training infrastructure that ensure the reliability and continuity of large-scale training runs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Help cultivate best practices in MLOps, and think about the full ML lifecycle, including data, fine-tuning, deployment, reliability and monitoring.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Possesses the ability to execute complex modifications to the research pipeline, such as fast data loading and distributed training.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Handle DevOps responsibilities, focused on making all engineers and researchers more productive. This includes tasks like cluster monitoring, unit testing and integration testing of research codebase, and continuous integration.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with partner researchers and engineers to deploy our technology within external infrastructure.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;5+ years of industry experience building and deploying machine learning infrastructure at scale.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with PyTorch, including custom training loops, distributed training, or low-level performance work.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with GPU-native data I/O tools and large-scale tensor formats (e.g. Zarr, HDF5, TensorStore, or similar).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with distributed computing frameworks such as Apache Spark, Dask, or Ray.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with containerization and orchestration tools such as Docker and Kubernetes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience building or working with AI agent frameworks is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A track record of building systems that other engineers and researchers depend on. Not just running experiments, but shipping infrastructure that scales.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is $214,000 to $335,000 annually. Final compensation is based on the level at which you are hired. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Please note that applying to this opportunity does not guarantee that we will be in touch with you regarding our opportunities. Our recruiting team will contact you if your experience aligns with the skills we seek for future open positions. We will keep your interest on file, contact you as opportunities arise, and send you information about the exciting work we are doing at Biohub. You can opt out at any time!\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347397,"name":"AI Research","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7793658","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3397435,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Artificial Intelligence","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will have the opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science.","value_type":"long_text"}],"id":7793658,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1643","title":"Machine Learning Engineer, AI","company_name":"Biohub","first_published":"2026-04-08T17:09:58-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world\u0026#39;s leading biologists. We\u0026#39;re not a startup trying to find product-market fit, and we\u0026#39;re not a pharma company optimizing a pipeline. We\u0026#39;re building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our research spans:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Imaging foundation models trained across the world\u0026#39;s largest microscopy datasets\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Reasoning and agentic systems that connect frontier LLMs with biological foundation models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Join our Team!\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As an ML Engineer, you\u0026#39;ll join some of the strongest infrastructure engineers in AI, building the systems that connect everything together. The infrastructure problems you solve directly determine what science becomes possible.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Work with high-dimensional scientific data formats and contribute to backend compatibility, format evaluation, and I/O performance benchmarking at petabyte scale.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define and shape the engineering patterns your team and collaborating researchers will build on for years; the abstractions you write today become the foundation others depend on at scale.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work at the intersection of AI systems and biological discovery, where the infrastructure problems you solve directly determine what science becomes possible.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deploy models to production and manage artifact tracking across models and datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and optimize GPU-native data loading pipelines for large-scale multi-dimensional tensor workloads, including profiling and resolving hardware utilization bottlenecks across multi-backend systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work on simplification and improvement of codebase abstractions to accelerate research momentum.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build and maintain primitives for pre-training infrastructure that ensure the reliability and continuity of large-scale training runs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Help cultivate best practices in MLOps, and think about the full ML lifecycle, including data, fine-tuning, deployment, reliability and monitoring.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Possesses the ability to execute complex modifications to the research pipeline, such as fast data loading and distributed training.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Handle DevOps responsibilities, focused on making all engineers and researchers more productive. This includes tasks like cluster monitoring, unit testing and integration testing of research codebase, and continuous integration.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with partner researchers and engineers to deploy our technology within external infrastructure.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;5+ years of industry experience building and deploying machine learning infrastructure at scale.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with PyTorch, including custom training loops, distributed training, or low-level performance work.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with GPU-native data I/O tools and large-scale tensor formats (e.g. Zarr, HDF5, TensorStore, or similar).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with distributed computing frameworks such as Apache Spark, Dask, or Ray.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with containerization and orchestration tools such as Docker and Kubernetes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience building or working with AI agent frameworks is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A track record of building systems that other engineers and researchers depend on. Not just running experiments, but shipping infrastructure that scales.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is $214,000 to $335,000 annually. Final compensation is based on the level at which you are hired. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Please note that applying to this opportunity does not guarantee that we will be in touch with you regarding our opportunities. Our recruiting team will contact you if your experience aligns with the skills we seek for future open positions. We will keep your interest on file, contact you as opportunities arise, and send you information about the exciting work we are doing at Biohub. You can opt out at any time!\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347397,"name":"AI Research","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7729207","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":3392223,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will build, scale, and automate next-generation molecular measurement technologies.  This role will lead the design and deployment of integrated automation systems that enable high-throughput, high-content, and reproducible experimentation across functional genomics, multi-omics profiling, and advanced cellular systems, including organoids and complex co-culture models.","value_type":"long_text"}],"id":7729207,"updated_at":"2026-06-02T16:50:14-04:00","requisition_id":"R1636","title":"Manager/ Director, Engineering","company_name":"Biohub","first_published":"2026-03-19T11:47:24-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/inflammation/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub seeks a\u0026amp;nbsp;\u0026lt;strong\u0026gt;\u0026lt;span style=\u0026quot; margin: 0px; padding: 0px;\u0026quot;\u0026gt;Manager/Director\u0026lt;/span\u0026gt;\u0026amp;nbsp;of Engineering\u0026lt;/strong\u0026gt; to build, scale, and automate next-generation\u0026amp;nbsp;molecular measurement technologies.\u0026amp;nbsp; This role will lead the design and deployment of integrated automation systems that enable high-throughput, high-content, and\u0026amp;nbsp;reproducible experimentation across functional genomics, multi-omics profiling, and\u0026amp;nbsp;advanced cellular systems, including organoids and complex co-culture models.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The position will translate cutting-edge biological objectives into robust, scalable, and automated laboratory infrastructure. The ideal candidate brings deep industry experience building and operating life science technology platforms, particularly in proteomics, functional genomics, transcriptomics, imaging-based assays, and/or organoid systems—combined with strong expertise in robotics, automation engineering, and instrument integration.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This leader will architect platforms that move beyond commoditized automation toward flexible, adaptive systems capable of executing complex biological protocols at scale, with tight integration between experimental workflows, data systems, and computational analysis pipelines.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Automation, Robotics, Instrumentation\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead the development and integration of advanced robotic systems for liquid handling, organoid handling, environmental control, and assay execution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee integration of molecular measurement technologies (e.g., spatial omics, proteomics, high-content imaging) directly into automated pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop custom hardware, fixtures, and accessories where commercial solutions are insufficient.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure seamless integration between robotic systems, LIMS, data pipelines, and downstream analysis infrastructure.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Industry \u0026amp;amp; Ecosystem Leadership\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Leverage deep industry knowledge to evaluate and implement best-in-class\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;commercial instrumentation, robotics platforms, and automation software.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build and manage strategic relationships with automation vendors, instrument\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;manufacturers, and contract engineering partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Conduct rigorous technical diligence of vendors and outsourced development\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define clear technical specifications, milestones, and quality standards for\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;external contributors.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify opportunities to translate internally developed platform innovations into\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Broader partnerships or collaborative networks.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Team Building \u0026amp;amp; Organizational Development\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Build and lead an interdisciplinary team of automation engineers, robotics engineers, platform scientists, and systems integration specialists.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Recruit individuals with deep technical rigor and strong understanding of biological systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish engineering best practices in documentation, validation, uptime management, and quality control.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Foster a culture that blends industrial engineering discipline with scientific innovation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and manage a blended team structure that includes internal staff and external partners.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Essential -\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ph.D. or M.S. in Bioengineering, Mechanical Engineering, Robotics, Chemical Engineering, or related field; or equivalent industry experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;10+ years of experience building and operating life science technology platforms in industry (biotech, pharma, or advanced technology companies).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated leadership in functional genomics, multi-omics platforms, or organoid-based systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise in laboratory automation, robotics, and systems integration.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven experience deploying scalable, production-grade biological platforms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong track record of vendor management, outsourced engineering oversight, and technical diligence.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience integrating automation systems with laboratory information systems and data pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to recruit, mentor, and lead high-performing multidisciplinary teams.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Preferred -\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience scaling CRISPR screening platforms or large-scale screening systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Background in organoid automation or complex tissue models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience integrating imaging-based phenotypic screening\u0026amp;nbsp;with molecular profiling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience building platforms designed for ML-ready or model-driven experimental workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience deploying multi-site or distributed automation platforms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with regulatory, quality, and compliance considerations in industrial biotech environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Direct experience with AI-guided experimental design or model-in-the-loop workflows.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Chicago, IL\u0026amp;nbsp; base pay range for a new hire in this role is Manager = $204,000 - $255,000, Director = $230,000 - $287,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7827048","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3415855,"location":{"name":"San Francisco, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Technology Platforms","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub San Francisco"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will develop and maintain robust control software for advanced light-sheet microscopes.","value_type":"long_text"}],"id":7827048,"updated_at":"2026-06-03T14:07:33-04:00","requisition_id":"R1677","title":"Optical Engineer, Advanced Light Sheet Microscopy","company_name":"Biohub","first_published":"2026-06-03T12:49:45-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Through our multi-dimensional imaging program, we build imaging tools that capture life across scales — from single proteins to whole organisms — revealing how proteins and cells function, communicate, and assemble into living systems. These observations are laying the groundwork for a new generation of AI models that can predict cellular behavior and guide the development of better treatments for widespread diseases. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/imaging/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our work brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;An overarching goal of the Biohub is to elucidate the complex collective dynamics of self-organizing cellular systems across scales in health and disease. To this end, we design, build, and use\u0026lt;a href=\u0026quot;https://www.nature.com/articles/s41592-022-01417-2\u0026quot;\u0026gt; state-of-the-art light-sheet microscopes\u0026lt;/a\u0026gt; to visualize wild-type and perturbed zebrafish embryonic development in living zebrafish as model vertebrate organisms. Lightsheet microscopes are powerful imaging instruments capable of resolving individual cells in 5D (=D+color+time) within entire living specimens. In this position, you will become an integral part of\u0026lt;a href=\u0026quot;https://twitter.com/loicaroyer\u0026quot;\u0026gt; Loic Royer\u0026lt;/a\u0026gt;’s\u0026lt;a href=\u0026quot;http://royerlab.org\u0026quot;\u0026gt; multidisciplinary team\u0026lt;/a\u0026gt; of computer scientists, optical engineers, and biologists focused on decoding how cells self-organize to build complex tissues, as exemplified by our recent\u0026lt;a href=\u0026quot;https://zebrahub.ds.czbiohub.org/\u0026quot;\u0026gt; work.\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We seek an \u0026lt;strong\u0026gt;Optical Engineer, Advanced Light Sheet Microscopy \u0026lt;/strong\u0026gt;with strong hands-on engineering skills, experience building and integrating scientific instrumentation, ideally lightsheet microscopes, and solid programming expertise for hardware control and automation. A successful candidate will combine practical advanced optical design and system-building experience with the ability to develop and maintain robust control software for advanced light-sheet microscopes. In this position, you will collaborate with scientists, bioengineers, computer scientists, and biologists to co-design and build our \u0026lt;a href=\u0026quot;https://vimeo.com/540518886\u0026quot;\u0026gt;imaging systems\u0026lt;/a\u0026gt;, optimise our instruments, and design automation of\u0026lt;a href=\u0026quot;https://vimeo.com/799695383\u0026quot;\u0026gt; time-lapse imaging\u0026lt;/a\u0026gt; of live specimens.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design, prototype, implement, and optimise custom subsystems for light-sheet microscopes and other advanced imaging platforms. Integrate mechanical, thermal, fluidic, optical, and electronic components into cohesive, reliable experimental systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop modular hardware control software in Python (and occasionally C/C++), interfacing with cameras, stages, lasers, sensors, and other instrumentation components.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and implement automated or “smart” imaging protocols incorporating feedback loops (e.g., sensor-driven control, adaptive imaging strategies, and real-time decision-making).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with scientists, bioengineers, computer scientists, and biologists to implement new features and capabilities, including hardware interfaces, acquisition modes, graphical user interfaces, smart automation, high-performance data visualization, and scalable data storage pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to data acquisition workflows capable of handling large-scale imaging datasets, including performance optimization, structured data saving, and integration with downstream analysis pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Document system architectures, mechanical designs, schematics, and assembly procedures to ensure reproducibility, maintainability, and scalability.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Master of Science, or PhD degree in Optics, Biomedical Engineering, Electrical Engineering, Mechanical Engineering, Robotics, or a related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong practical engineering skills with demonstrated experience designing, prototyping, and iterating hardware control systems (at least 5 years).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Solid working knowledge of electronics and embedded systems, including microcontrollers, DACs/ADCs, and basic PCB design (at least 4 years).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with CAD design (e.g., SolidWorks, OnShape, or similar) and rapid prototyping methods such as 3D printing, machining, laser cutting (at least 3 years)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong programming experience in Python; Experience with C/C++/Rust desired (at least 5 years).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven experience developing hardware control scripts and integrating third-party devices.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to troubleshoot complex mechanical, electrical, and software systems in experimental or research environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong communication skills and a collaborative mindset; ability to work effectively within a multidisciplinary team.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Nice to have\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Any tangible ‘extra-curricular’ evidence of exceptional abilities in the disciplines above, such as hobby projects in robotics, electronics, optics, DIY instrumentation, open-source hardware/software, are extremely welcome.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge and experience in light-sheet microscopy or other similar precision optical instruments are highly desirable.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience or interest in integrating Adaptive Optics (AO) components (e.g., deformable mirrors)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with feedback control systems, sensors, and real-time automation. Experience designing or integrating thermal control, microfluidic, perfusion, or environmental control systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience and deep understanding of low-level coding in C and C++.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with high-performance computing concepts (multi-threading, GPU acceleration, parallel processing) for image processing or data-intensive applications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with Linux-based systems and device driver configuration.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with optical metrology, such as PSF characterization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working in a biological or life sciences research environment.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The San Francisco, CA base pay range for a new hire in this role is $153,000.00 - $191,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287574,"name":"CZ Biohub SF, LLC","location":null,"child_ids":[287575,287576,287577],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7778933","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3405356,"location":{"name":"New York, NY (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Technology Platforms","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub New York"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will integrate foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed.","value_type":"long_text"}],"id":7778933,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1665","title":"Postdoctoral Fellow, Functional Genomics ","company_name":"Biohub","first_published":"2026-04-17T12:59:09-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research ev\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our \u0026lt;strong\u0026gt;Immune Cell Reprogramming\u0026lt;/strong\u0026gt; team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/immune-cell-reprogramming/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a highly motivated \u0026lt;strong\u0026gt;Postdoctoral Fellow\u0026lt;/strong\u0026gt; to lead development of pooled functional genomics technologies at scale, with emphasis on CRISPR technologies (CRISPRi, CRISPRa, CRISPRoff, and CRISPR base editing) in iPSC-derived immune cells and primary immune cells.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The role involves designing, optimizing, and validating new pooled CRISPR workflows and driving projects that provide new insights for immune system reprogramming and training foundational AI models. This position offers the opportunity to develop and own an independent research project—with potential to publish and present findings—while contributing to the team\u0026#39;s broader collaborative efforts.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a wet lab-based, hands-on position that specifically requires experience with functional genomics method development and high-volume human cell culture. It offers the opportunity to develop and implement assays, conduct perturbation experiments, oversee data generation, and participate in follow-up discovery collaborations.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role is ideal for a recent PhD with a proven track record in functional genomics and human cell culture (particularly iPSC culture) who excels at multitasking genomics projects and developing cutting-edge CRISPR genomics technologies. You will join a highly collaborative team at the forefront of massive-scale perturbation technologies and AI model development to predict how to reprogram the immune system to prevent, identify, and treat human disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This researcher will be based at our Satellite site in NYC integrated with a team specializing in advanced functional genomics technologies, particularly massive-scale pooled CRISPR screens and single-cell profiling, to understand immune cell regulation. The team sits at the intersection of next-generation wet-lab genomics technologies and AI model development.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Essential -\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Massive-scale Perturb-seq:\u0026amp;nbsp;\u0026lt;/strong\u0026gt;Design, optimize, scale, and carry out large-scale Perturb-seq experiments in iPSC-derived immune cells and immortalized cell lines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Assay development: \u0026lt;/strong\u0026gt;Design, optimize, and validate CRISPR functional genomics technologies to obtain higher quality, more complex data about cell-state regulation in human cells.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Immune cell engineering: \u0026lt;/strong\u0026gt;Culture and differentiate iPSCs into immune cell types such as T-cells and macrophages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Data generation: \u0026lt;/strong\u0026gt;Partner with AI researchers to process and interpret large-scale single-cell datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Collaboration and dissemination: \u0026lt;/strong\u0026gt;Collaborate across disciplines to understand systems-level reprogramming of human immune cells.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Nice to have -\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with CRISPR screening in iPSCs and primary immune cells.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience analyzing large-scale genomics datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of R or Python and single-cell analysis tools.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with cytokine or small molecule immune cell assays.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in molecular biology, systems biology, genetics, biomedical engineering, or related field\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven expertise and demonstrated success in large-scale functional genomics assays and method development\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience designing and executing pooled CRISPR screens and/or compound perturbation assays\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication skills and proven ability to work in a collaborative team environment\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to independently design rigorous experiments, troubleshoot complex workflows, and drive projects to completion.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborative mindset and strong scientific communication skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The New York City, NY base pay range for a new hire in this role is $93,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid #LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":305998,"name":"Platform","child_ids":[],"parent_id":305996}],"offices":[{"id":287573,"name":"CZ Biohub NY, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7902395","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3419464,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Science Programs","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will be embedded in interdisciplinary teams applying and developing high-throughput single-cell genomics approaches to understand inflammatory disease mechanisms. The successful candidate will design and execute quantitative experiments—using sequencing, imaging, bioengineering, or complementary profiling technologies—to dissect cellular heterogeneity, immune cell states, and tissue-level responses in complex biological systems. This role emphasizes both experimental rigor and computational fluency in the analysis of large-scale, high-dimensional datasets.","value_type":"long_text"}],"id":7902395,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1680","title":"Post-Doctoral Fellow, High-Throughput Functional Genomics","company_name":"Biohub","first_published":"2026-05-06T22:50:07-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif; font-size: 14px;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our Vision\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;We pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;We enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub Chicago seeks outstanding early-career experimental scientists with expertise in high-throughput profiling and quantitative biology to join as a Postdoctoral Research Scholar working on single-cell genomics problems in the inflammation space. We welcome candidates from diverse experimental backgrounds—whether rooted in sequencing, imaging, bioengineering, or other modalities—who bring rigorous quantitative thinking and a drive to tackle complex biological questions. This role offers a unique opportunity to work hands-on in a generously funded, highly collaborative environment at the intersection of technology development, bioengineering, and disease-focused discovery.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Postdoctoral Research Scholars will be embedded in interdisciplinary teams applying and developing high-throughput single-cell genomics approaches to understand inflammatory disease mechanisms. The successful candidate will design and execute quantitative experiments—using sequencing, imaging, bioengineering, or complementary profiling technologies—to dissect cellular heterogeneity, immune cell states, and tissue-level responses in complex biological systems. This role emphasizes both experimental rigor and computational fluency in the analysis of large-scale, high-dimensional datasets.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position provides strong mentorship alongside meaningful scientific independence within a team-science model that emphasizes collaboration across experimental, computational, and engineering domains. Projects align with the Biohub\u0026#39;s mission to uncover fundamental disease mechanisms and to develop transformative measurement technologies that accelerate biomedical research. Biohub Chicago is deeply committed to training scientists for impactful careers in academia, industry, and beyond.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design and execute quantitative, high-throughput experiments linking perturbations to the function of immune and inflammatory systems.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Develop, optimize, and apply perturbation readout workflows—including sequencing-based, imaging-based, or multimodal approaches—with rigorous method development, benchmarking, and quality control.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Collaborate closely with interdisciplinary teams spanning immunology, genomics, computation, and bioengineering to address open questions in inflammation biology.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Analyze and interpret large-scale, high-dimensional datasets using computational and statistical approaches, and communicate results clearly through figures, presentations, and internal discussions.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Disseminate research outputs through high-impact publications, preprints, and open scientific resources, contributing to a culture of open and collaborative science.\u0026lt;br\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in genomics, bioengineering, quantitative biology, systems immunology, computational biology, or a related quantitative life-science field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with core wet-lab molecular and cellular biology techniques, as well as high-throughput profiling methods.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience in quantitative molecular and cellular biology techniques and high-throughput profiling approaches.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated expertise in quantitative interpretation of complex, high-dimensional datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong record of scientific productivity, creativity, and collaborative problem-solving in interdisciplinary research environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Motivation to pursue innovative, independent research aligned with the Biohub’s mission and to thrive in a hands-on, team-science culture.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Experience with high-throughput profiling platforms (e.g., single-cell RNA-seq, spatial transcriptomics, multiplexed imaging, flow/mass cytometry, or proteomics\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Experience working with primary human cells.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Experience with technology or assay development, molecular barcoding, novel nucleic acid technologies, or quantitative imaging methods.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Background in immunology, inflammation biology, or related disease areas.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Chicago, IL base pay range for a new hire in this role is $71,000-$84,150. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a onsite position requiring you to be in office for 100% of the working month, approximately 5 days a week.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":305996,"name":"Technology Platforms","child_ids":[305997,305998],"parent_id":80776}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7779105","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3395302,"location":{"name":"New York, NY (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub New York"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will develop novel methods and tools to determine the migratory dynamics of immune cells, with focus on T cells, and how that affects their cellular profile, function and longevity.","value_type":"long_text"}],"id":7779105,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1638","title":"Postdoctoral Fellow - Immune Cell Dynamics - Optogenetics","company_name":"Biohub","first_published":"2026-04-03T16:40:49-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/immune-cell-reprogramming/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Parsa Lab, also known as the Immune Cell Dynamics and Function group, is currently accepting applications for a Postdoctoral fellow position. The Parsa group focuses on investigating the cellular and functional dynamics of T cells, exploring how T cell fate decisions are made and how these decisions impact their functions in different disease contexts. Using a combination of genetically engineered mice, disease models, and single-cell technologies, we aim to uncover the principles governing T cell fate and their functional roles across tissues. This position is to develop novel methods and tools to determine the migratory dynamics of immune cells, with focus on T cells, and how that affects their cellular profile, function and longevity. It is an outstanding opportunity to collaborate with a team of talented scientists working to address fundamental immunological questions, with potential applications in treating inflammatory disorders, autoimmunity, and cancer. More information can be found at\u0026lt;a href=\u0026quot;https://parsalab.org\u0026quot;\u0026gt; https://parsalab.org\u0026lt;/a\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Interested candidates should submit the following documents:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Cover Letter\u0026lt;/strong\u0026gt; detailing research interests, motivations and career goals.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Full version of Curriculum Vitae (CV)\u0026lt;/strong\u0026gt;\u0026amp;nbsp;highlighting major achievements, summary of a significant publication, and includes contact information for 3 references (letters will be requested as needed)\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Conduct independent and collaborative research in immunology and related areas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and perform in vitro and in vivo immune cell assessment\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish tools and perform assays to assess immune cell migration\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design, execute and analyze experiments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Present experimental data (in both written and oral formats)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prepare manuscripts for publication in peer-reviewed journals\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Follow advances in the field through published literature and conferences\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work closely with fellow team members and other members at Biohub institutions\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mentor research assistants and interns in the lab\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Essential:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD degree in immunology, molecular biology, genetics, biochemistry, or a related field\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in molecular cloning, CRISPR gene editing, and generation of constructs for viral transduction methods\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A strong sense of curiosity and drive to explore\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to conduct independent research and work in a team\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication skills (both verbal and written)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to collaborate in a diverse environment\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Strong applicants have skills in one or more of the following areas:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience working with mice, particularly generating transgenic or genetically modified primary T cells (and mice).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with flow cytometry and microscopy (particularly bioluminescence and fluorescence microscopy), and other imaging modalities to detect and quantify reporter gene expression\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong knowledge of the existing literature in immunology, dogmas and challenges\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The New York City, NY\u0026amp;nbsp; base pay range for a new hire in this role is $93,000.00.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":58664,"name":"Chan Zuckerberg Initiative","location":"Redwood City, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7769739","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3396342,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will design and execute longitudinal transcriptomics experiments to investigate dynamic gene expression and transcriptional heterogeneity in immune-competent organoid systems.","value_type":"long_text"}],"id":7769739,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1641","title":"Postdoctoral Fellow, Live Tissue Omics","company_name":"Biohub","first_published":"2026-03-31T17:27:38-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;Our Vision\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;We pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;We enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub Chicago seeks outstanding early-career scientists and engineers to join its Quantitative Live Tissue Transcriptomics platform as a Postdoctoral Research Scholar in longitudinal and single-cell profiling. This role offers a unique opportunity to work hands-on in a generously funded, highly collaborative environment at the intersection of technology development, biology, and disease-focused discovery.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Postdoctoral Research Scholars will be embedded in interdisciplinary teams developing and applying next-generation transcriptomic workflows for non-destructive, time-resolved measurements from living cells and tissues. A central focus of this role is understanding how dynamic gene expression and cell-to-cell transcriptional heterogeneity shape the behavior of immune-competent organoid and ex vivo systems. The successful candidate will leverage emerging live-sampling technologies to interrogate cellular dynamics, immune–tissue interactions, and emergent phenotypes that are inaccessible with static, endpoint approaches.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position provides strong mentorship alongside meaningful scientific independence within a team-science model that emphasizes collaboration across experimental, computational, and engineering domains. Projects align with the Biohub\u0026#39;s mission to uncover fundamental disease mechanisms and to develop transformative measurement technologies that accelerate biomedical research. Biohub Chicago is deeply committed to training scientists for impactful careers in academia, industry, and beyond.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and execute longitudinal transcriptomics experiments to investigate dynamic gene expression and transcriptional heterogeneity in immune-competent organoid systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop, optimize, and apply advanced RNA profiling workflows for non-destructive, time-resolved sampling from living cells and tissues, including method development, benchmarking, and quality control.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate closely with interdisciplinary teams spanning tissue engineering, immunology, computation, and instrumentation to build and interrogate increasingly complex immune-organoid models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyze and interpret large-scale transcriptomics and lineage barcoding datasets using state-of-the-art computational pipelines, and communicate results clearly through figures, presentations, and internal discussions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Disseminate research outputs through high-impact publications, preprints, and open scientific resources, contributing to a culture of open and collaborative science.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in genomics, bioengineering, quantitative biology, systems immunology, computational biology, or a related quantitative life-science field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with quantitative molecular and cell biology techniques and high-throughput profiling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated expertise in quantitative interpretation of complex, high-dimensional datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong record of scientific productivity, creativity, and collaborative problem-solving in interdisciplinary research environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Motivation to pursue innovative, independent research aligned with the Biohub’s mission and to thrive in a hands-on, team-science culture.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Experience with sequencing platforms and transcriptomics workflows (e.g., RNA-seq, single-cell RNA-seq, or spatial transcriptomics).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Experience with RNA engineering, molecular barcoding, or novel nucleic acid technologies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Background in immune cell biology, immune–tissue interactions, or organoid model systems.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Chicago, IL base pay for a new hire in this role is $84,150. This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;\u0026amp;nbsp;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7962142","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3456976,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["Science"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":null,"value_type":"long_text"}],"id":7962142,"updated_at":"2026-06-03T13:39:59-04:00","requisition_id":"R1704","title":"Postdoctoral Fellow, Microtissue Signaling Dynamics ","company_name":"Biohub","first_published":"2026-06-03T13:39:59-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We study how cells within tissues communicate through biochemical signals during disease and immune responses. By collecting multimodal data from tissues and developing advanced microfluidic platforms, we aim to uncover the core mechanisms that drive disease progression and treatment responses. Integrating experimental data with computational approaches—including network modeling, information theory, and machine learning—we seek to identify the most informative indicators of disease state and develop more effective therapeutic strategies for autoimmune diseases and cancer.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub Chicago seeks outstanding early-career experimental scientists with expertise in microfluidics and quantitative biology to join as a \u0026lt;strong\u0026gt;Postdoctoral Fellow\u0026lt;/strong\u0026gt; developing innovative devices for culturing and testing various tissues. We welcome candidates from diverse experimental backgrounds—whether rooted in microfluidics, imaging, bioengineering, or other modalities—who bring rigorous quantitative thinking and a drive to tackle complex biological questions. This role offers a unique opportunity to work hands-on in a generously funded, highly collaborative environment at the intersection of technology development, bioengineering, and disease-focused discovery.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Postdoctoral Fellows\u0026amp;nbsp; will be embedded in interdisciplinary teams applying and developing microfluidic devices to simulate various inflammatory disease mechanisms with focus on skin tissue and/or gut tissue model. The successful candidate will design and execute quantitative experiments—using imaging, fluid handling, automation, or complementary profiling technologies—to dissect cellular heterogeneity, immune cell states, and tissue-level responses in complex biological systems. This role emphasizes both experimental rigor and computational fluency in the analysis of large-scale, high-dimensional datasets.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Projects align with the Biohub\u0026#39;s mission to uncover fundamental disease mechanisms and to develop transformative measurement technologies that accelerate biomedical research. Biohub Chicago is deeply committed to training scientists for impactful careers in academia, industry, and beyond.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop microfluidic platforms for skin and/or gut tissue.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop the code to operate various components in the integrated system including fluidic handling (robotic pipette), other mechanical and electrical parts, and imaging.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Perform the experiments to simulate various disease scenarios.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026amp;nbsp;Analyze the data: sequential volumetric images and cytokines or other protein profiles in the biofluid in collaboration with other teams in Biohub.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Actively collaborate with other teams in the Biohub.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Programming including Matlab, python, and/or C++.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Cleanroom/Soft lithography experience (Laser writer, spin-coating, DRIE, etc).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Multilayer microfluidic device fabrication.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with handling mammalian cell or tissues.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with advanced microscopy (confocal and/or light-sheet microscopy) Image analysis.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Chicago, IL base pay range for a new hire in this role is $84,150. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid #LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7922556","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3443835,"location":{"name":"New York, NY (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub New York"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will lead the design, optimization, and benchmarking of a new single-cell method for studying gene regulatory networks and apply it in patient biopsy samples and organoid models.","value_type":"long_text"}],"id":7922556,"updated_at":"2026-06-02T20:11:33-04:00","requisition_id":"R1690","title":"Postdoctoral Fellow/ Scientist I, Single-Cell Method Development","company_name":"Biohub","first_published":"2026-05-18T12:07:29-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The\u0026amp;nbsp;\u0026lt;strong\u0026gt;Chan Zuckerberg Biohub New York\u0026amp;nbsp;\u0026lt;/strong\u0026gt;(CZ Biohub NY, \u0026lt;a href=\u0026quot;https://www.czbiohub.org/ny/\u0026quot;\u0026gt;https://www.czbiohub.org/ny/\u0026lt;/a\u0026gt;) is an independent nonprofit research institute that brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. CZ Biohub NY itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;strong\u0026gt; \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;We pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;We enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;The technologies developed at CZ Biohub facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an inclusive organization where all colleagues feel inspired and know their work makes an important contribution.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The \u0026lt;strong\u0026gt;Laboratory of Immunogenomics\u0026lt;/strong\u0026gt; at \u0026lt;strong\u0026gt;CZ Biohub NY\u0026lt;/strong\u0026gt; (\u0026lt;a href=\u0026quot;http://www.mahatlab.com\u0026quot;\u0026gt;www.mahatlab.com\u0026lt;/a\u0026gt;) studies the non-coding regulatory genome to understand and address immune dysfunction in diseases like cancer, autoimmune disorders, and aging. We focus on enhancers—non-coding, highly cell–type–specific transcriptional regulatory elements—and their role in shaping immune responses. We develop and utilize genomic technologies, including bulk and single-cell nascent RNA sequencing, genome editing, immune engineering, and CRISPR-based functional screens in patient biopsies, organoid systems, and mouse models. Through computational analysis integrating machine learning and AI, we map enhancer–gene networks and identify disease-driving elements. Our goal is to advance enhancer-guided precision genomic medicine for diseases involving immune dysfunction.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a highly motivated \u0026lt;strong\u0026gt;Postdoctoral Fellow/ Scientist I\u0026lt;/strong\u0026gt; to lead the development of a high-throughput adaptation of a newly established single-cell nascent RNA sequencing method (scGRO-seq) and apply it to patient biopsies and organoid models. The role involves designing, optimizing, and benchmarking cutting-edge single-cell genomics workflows, integrating them with perturbation-based assays, and generating datasets that drive transformative insights into immune regulation.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a wetlab-based, hands-on position that specifically requires experience in method development and offers the opportunity to develop and implement the assay, conduct perturbation experiments, and oversee data generation. Once the workflow is established, this position will coordinate large-scale data acquisition and collaborate with computational biologists on downstream analyses to deliver actionable translational insights. This role is ideal for a recent PhD with a proven track record in single-cell biology who excels at the intersection of technological innovation and transcription regulation. You will join a highly collaborative team working toward a shared vision at the cutting-edge of single-cell immunogenomics.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Assay development:\u0026lt;/strong\u0026gt; Design, optimize, and scale high-throughput single-cell/nuclei extraction, barcoding, and library preparation workflows for scGRO-seq.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Perturbation integration:\u0026lt;/strong\u0026gt; Combine scGRO-seq with CRISPR-based enhancer perturbation, drug treatments, and multi-omics profiling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Molecular biology techniques:\u0026lt;/strong\u0026gt; Execute advanced methods including assay design, cell manipulation, RNA/DNA isolation, PCR/qPCR, NGS library construction, high-dimensional flow cytometry, and sequencing.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Translational applications:\u0026lt;/strong\u0026gt; Adapt and validate protocols in patient biopsies and 3D organoid models, with emphasis on reproducibility and sensitivity.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Immune cell engineering:\u0026lt;/strong\u0026gt; Isolate, culture, and reprogram hematopoietic stem/progenitor cells (HSPCs) and primary immune subsets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Data integration:\u0026lt;/strong\u0026gt; Partner with computational biologists to process and interpret large-scale single-cell datasets (RNA, chromatin, proteomics).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; dissemination:\u0026lt;/strong\u0026gt; Collaborate across disciplines to investigate regulatory genomics in immune dysfunction, tumor-infiltrating immune cells, and autoimmune disease variants. Contribute to publications, preprints, conference presentations, and grant proposals.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Essential:\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Biomedical Engineering, Molecular Biology, Systems Biology, Genetics, or related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;4+ years of experience working in genomics assay development or method optimization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;2+ years of experience working on single-cell transcriptomics, droplet chemistry, and microfluidics.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven expertise and demonstrated success in bulk or single-cell method development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience designing and executing CRISPR screens and perturbation assays (genetic or chemical/drug).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong problem-solving skills, independence, and the ability to troubleshoot complex workflows.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication skills and proven ability to work in collaborative, multidisciplinary teams.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Nice to have:\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience and broad domain knowledge in microfluidic-based single-cell methods.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with hydrogel synthesis, single-cell barcoded bead generation, and aqueous droplets in oil emulsions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with functional genomics in immune cells.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience integrating multi-modal single-cell datasets (RNA, ATAC, proteomics).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Working knowledge of Linux/HPC environments and single-cell analysis tools (e.g., Seurat, Scanpy).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The New York, NY base pay for a new hire in this role is Postdoctoral Fellow = $93,000.00, Scientist I = $120,000 - $150,000. This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287573,"name":"CZ Biohub NY, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7769713","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3396340,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will bring PhD in genomics, bioengineering, quantitative biology, systems immunology, computational biology, or a related quantitative life-science field.","value_type":"long_text"}],"id":7769713,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1640","title":"Postdoctoral Fellow, Single-Cell Genomics","company_name":"Biohub","first_published":"2026-03-31T17:05:51-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;Our Vision\u0026lt;/h3\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;We pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;We enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.\u0026lt;/p\u0026gt;\n\u0026lt;h3\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h3\u0026gt;\n\u0026lt;p\u0026gt;Biohub Chicago seeks outstanding early-career experimental scientists with expertise in high-throughput profiling and quantitative biology to join as a Postdoctoral Research Scholar working on single-cell genomics problems in the inflammation space. We welcome candidates from diverse experimental backgrounds—whether rooted in sequencing, imaging, bioengineering, or other modalities—who bring rigorous quantitative thinking and a drive to tackle complex biological questions. This role offers a unique opportunity to work hands-on in a generously funded, highly collaborative environment at the intersection of technology development, bioengineering, and disease-focused discovery.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Postdoctoral Research Scholars will be embedded in interdisciplinary teams applying and developing high-throughput single-cell genomics approaches to understand inflammatory disease mechanisms. The successful candidate will design and execute quantitative experiments—using sequencing, imaging, bioengineering, or complementary profiling technologies—to dissect cellular heterogeneity, immune cell states, and tissue-level responses in complex biological systems. This role emphasizes both experimental rigor and computational fluency in the analysis of large-scale, high-dimensional datasets.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position provides strong mentorship alongside meaningful scientific independence within a team-science model that emphasizes collaboration across experimental, computational, and engineering domains. Projects align with the Biohub\u0026#39;s mission to uncover fundamental disease mechanisms and to develop transformative measurement technologies that accelerate biomedical research. Biohub Chicago is deeply committed to training scientists for impactful careers in academia, industry, and beyond.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and execute quantitative, high-throughput experiments to investigate cellular heterogeneity and gene expression dynamics in immune and inflammatory systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop, optimize, and apply single-cell profiling workflows—including sequencing-based, imaging-based, or multimodal approaches—with rigorous method development, benchmarking, and quality control.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate closely with interdisciplinary teams spanning immunology, genomics, computation, and bioengineering to address open questions in inflammation biology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyze and interpret large-scale, high-dimensional datasets using computational and statistical approaches, and communicate results clearly through figures, presentations, and internal discussions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Disseminate research outputs through high-impact publications, preprints, and open scientific resources, contributing to a culture of open and collaborative science.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in genomics, bioengineering, quantitative biology, systems immunology, computational biology, or a related quantitative life-science field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with quantitative molecular and cell biology techniques and high-throughput profiling.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated expertise in quantitative interpretation of complex, high-dimensional datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong record of scientific productivity, creativity, and collaborative problem-solving in interdisciplinary research environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Motivation to pursue innovative, independent research aligned with the Biohub’s mission and to thrive in a hands-on, team-science culture.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Experience with high-throughput profiling platforms (e.g., single-cell RNA-seq, spatial transcriptomics, multiplexed imaging, flow/mass cytometry, or proteomics).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Experience with technology or assay development, molecular barcoding, novel nucleic acid technologies, or quantitative imaging methods.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;[Nice to have] Background in immunology, inflammation biology, or related disease areas.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Chicago, IL base pay for a new hire in this role is $84,150. This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7658780","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3372303,"location":{"name":"New York, NY (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub New York"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will investigate how transcription factors regulate gene expression programs in cancer and how disease-associated mutations in transcription factors disrupt these programs to drive malignant phenotypes.","value_type":"long_text"}],"id":7658780,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1617","title":"Postdoctoral Fellow, Transcription Regulation using Genomics and Machine Learning","company_name":"Biohub","first_published":"2026-03-02T18:36:17-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/immune-cell-reprogramming/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The \u0026lt;strong\u0026gt;Laboratory of Immunogenomics\u0026lt;/strong\u0026gt; at \u0026lt;strong\u0026gt;CZ Biohub NY\u0026lt;/strong\u0026gt; (\u0026lt;a href=\u0026quot;http://www.mahatlab.com\u0026quot;\u0026gt;www.mahatlab.com\u0026lt;/a\u0026gt;) studies the non-coding regulatory genome to understand and address immune dysfunction in diseases like cancer, autoimmune disorders, and aging. We focus on enhancers—non-coding, highly cell–type–specific transcriptional regulatory elements—and their role in shaping immune responses.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We develop and utilize genomic technologies, including bulk and single-cell nascent RNA sequencing, genome editing, immune engineering, and CRISPR-based functional screens in patient biopsies, organoid systems, and mouse models. Through computational analysis integrating machine learning and AI, we map enhancer–gene networks and identify disease-driving elements. Our goal is to advanc\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We seek a Postdoctoral Fellow to investigate how transcription factors regulate gene expression programs in cancer and how disease-associated mutations in transcription factors disrupt these programs to drive malignant phenotypes. Many cancer-linked alterations affect transcription factor binding, chromatin engagement, and transcriptional output, yet the downstream regulatory mechanisms and disease consequences remain incompletely understood. This project aims to define the molecular functions of transcription factors in normal and diseased states, map how mutations alter chromatin and transcriptional regulation, and utilize machine learning to predict and test novel mutant-TF-specific functions.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Transcription Factor Mechanism Discovery\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Define how transcription factors control gene expression, chromatin accessibility, and regulatory element activity in cancer-relevant cellular contexts.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Map transcription factor occupancy, chromatin state, and nascent transcription using GRO-seq/ PRO-seq, CUT\u0026amp;amp;RUN, ATAC-seq, DNA methylation profiling.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Integrate transcription factor binding data with enhancer activity, promoter usage, and transcriptional outputs to identify direct regulatory targets and core gene networks.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Apply CRISPR editing to test candidate genes, regulatory elements, and pathways.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Mutation-Driven Regulatory Analysis\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Determine how cancer-associated mutations in transcription factors alter DNA binding, cofactor recruitment, chromatin remodeling, and transcriptional control.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Compare wild-type and mutant transcription factor function across genomic, epigenomic, and transcriptional assays to identify mutation-specific regulatory defects.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Characterize the mutated-TF-associated co-factors, transcription factor, chromatin remodeling through protein-protein interactions.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Dissect how these changes impact oncogenic pathways, lineage identity, cellular plasticity, and disease progression.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;AI/ML-Guided Functional Discovery\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Collaborate closely with AI/ML scientists to apply protein language models and related computational approaches to transcription factors and their disease-associated variants.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Use these models to predict potential novel molecular functions, protein-protein interaction partners, and mutation-associated cellular phenotypes.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Design and execute experimental strategies to test model-derived predictions in laboratory settings, using genomic, molecular, and functional assays to validate predicted mechanisms and disease-relevant consequences.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Help establish an iterative framework in which computational predictions inform experiments, and experimental results refine downstream modeling and hypothesis generation.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Genomic Library Preparation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Lead and optimize genomic library preparation workflows for chromatin and transcription-focused assays, with strong emphasis on GRO-seq/PRO-seq, CUT\u0026amp;amp;RUN, ATAC-seq, DNA methylation assays, and RNA-seq.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Generate high-quality sequencing libraries from cell lines, engineered models, and primary samples, ensuring rigorous experimental design, QC, and reproducibility.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Support comparative profiling across perturbation conditions, mutant backgrounds, and treatment states to reveal context-specific transcription factor biology.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Molecular and Cell Biology Validation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Perform core molecular biology methods, including tissue culture, organoid and patient sample processing, ChIP, gel electrophoresis, cloning, FACS, and ELISA etc., to validate mechanistic hypotheses.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Use genome engineering and perturbation approaches, including CRISPR-based editing and CRISPR screening, to test the functional consequences of transcription factor mutations and candidate regulatory dependencies.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Validate key findings through orthogonal assays in relevant cellular models.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Pathway Integration and Disease Modeling\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Identify critical downstream effectors, co-factors, and candidate therapeutic vulnerabilities emerging from mutant transcription factor activity.\u0026lt;/p\u0026gt;\n\u0026lt;p style=\u0026quot;padding-left: 40px;\u0026quot;\u0026gt;- \u0026amp;nbsp; Contribute to the development of mechanistic frameworks explaining how transcription factor dysfunction gives rise to disease.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Essential\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Molecular Biology, Cancer Biology, Genetics, Genomics, or a related field.\u0026lt;br\u0026gt;Strong hands-on experience in genomic library preparation, particularly for chromatin and transcription-focused assays such as GRO-seq/PRO-seq, CUT\u0026amp;amp;RUN, ATAC-seq, DNA methylation profiling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in basic molecular biology techniques, mammalian cell culture, engineered cell models, and/or primary samples.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with functional perturbation methods such as CRISPR editing, CRISPR screening, or other genetic manipulation approaches.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated work and publication in transcription factor biology, gene regulation, epigenomics, or cancer mechanisms, reflecting independent experimental work and mechanistic biological insight.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Preferred\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with computational biology methods and genomic data analyses.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience studying transcription factors, chromatin regulators, or gene regulatory mechanisms in cancer or other disease contexts.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with comparing wild-type and mutant protein function using genomic and molecular assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Interest in collaborative, interdisciplinary research at the interface of transcription, epigenetics, and disease biology.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-size: 12pt;\u0026quot;\u0026gt;The New York, NY base pay for a new hire in this role is Postdoctoral Fellow = $93,000.00. This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287573,"name":"CZ Biohub NY, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7834914","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3404931,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will support the deployment, operation, and continuous improvement of an advanced automated laboratory platform. This role is responsible for ensuring reliable execution of complex workflows through the integration of robotics, instrumentation, and control systems.\nYou will play a key role in building and maintaining the infrastructure that enables scalable and efficient experimental operations.","value_type":"long_text"}],"id":7834914,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1660","title":"R\u0026D Engineer, Laboratory Automation \u0026 Robotics","company_name":"Biohub","first_published":"2026-04-21T00:05:01-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our Vision\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;We pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;We enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We are seeking an R\u0026amp;amp;D Engineer to support the deployment, operation, and continuous improvement of an advanced automated laboratory platform. This role is responsible for ensuring reliable execution of complex workflows through the integration of robotics, instrumentation, and control systems.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will play a key role in building and maintaining the infrastructure that enables scalable and efficient experimental operations.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop scalable, modular automation architectures to support evolving experimental needs across multiple hardware platforms\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with computational teams to enable closed-loop / data-driven experimentation\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate and support installation, configuration, and integration of laboratory automation systems and instrumentation\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Optimize high-throughput experimental pipelines\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Program and coordinate robotic systems and instrument control software\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Perform routine maintenance, calibration, and validation of equipment\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Implement real-time monitoring and logging systems for workflow performance and data quality\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Monitor system reliability and implement improvements to increase efficiency and uptime\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Troubleshoot hardware and workflow issues to ensure consistent system performance\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with scientific teams to translate experimental needs into automated processes\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide technical support and training to users of the platform\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;BS or MS in Mechanical Engineering, Electrical Engineering, Bioengineering, Robotics, or a related field\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;5+ years of professional, hands-on experience with laboratory automation systems, robotics, or complex instrumentation\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Experience with hardware integration and control systems\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Programming or scripting experience (e.g., Python or vendor-specific platforms)\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong troubleshooting skills and attention to detail\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Ability to manage and maintain complex systems in a dynamic environment\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Effective communication skills and a collaborative mindset\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong problem-solving skills and a systems-level mindset\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Interest in data-driven experimentation and automated platforms\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Chicago, IL base pay range for a new hire in this role is $130,000 - $138,550. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a onsite position requiring you to be onsite for at least 100% of the working month, approximately 5 days a week.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7835072","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3404930,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Science Programs","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago","Science"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will execute and optimize experiments that feed directly into a screening platform designed to map immune antigens in inflammation.","value_type":"long_text"}],"id":7835072,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1663","title":"Research Associate, NGS Assay Development, Virtual Immune System","company_name":"Biohub","first_published":"2026-04-21T01:20:58-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work \u0026lt;a href=\u0026quot;https://biohub.org/inflammation/\u0026quot;\u0026gt;here\u0026lt;/a\u0026gt;.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Our Vision\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Pursue large scientific challenges that cannot be pursued in conventional environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Enable individual investigators to pursue their riskiest and most innovative ideas\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Facilitate research by scientists and clinicians at our home institutions and beyond\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub is seeking a Research Associate to join the Cell Decoder team within the Virtual Immune System initiative. This is a hands-on bench role centered on molecular biology, cell engineering, and genomics workflows, including bacterial and mammalian cell culture, plasmid cloning, lentiviral production, library preparation, and flow cytometry. You\u0026#39;ll execute and optimize experiments that feed directly into a screening platform designed to map immune antigens in inflammation.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position is ideal for someone who thrives on bench work, takes pride in reliable execution, and actively looks for ways to make things run better. That could mean optimizing a viral production protocol, reorganizing a reagent inventory system, or finding a more efficient way to coordinate a multi-day, multi-step experiment. You won\u0026#39;t just follow protocols; you\u0026#39;ll help build and refine them. You\u0026#39;ll join a small, experienced team with direct mentorship and exposure to how AI/ML and computational approaches are shaping experimental immunology.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Perform molecular biology workflows including bacterial culture, plasmid cloning, mini/midi preps, and construct verification to generate reagents for cell engineering experiments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain mammalian cell lines (Jurkat, 293T, K562) including passaging, selection, and banking — serving as a reliable backbone for ongoing assay development.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Produce and package lentiviral vectors, troubleshoot viral production workflows, and execute transduction experiments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Execute single-cell genomics and sequencing workflows, including 10x Genomics library preparation and next-generation sequencing library QC.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Perform flow cytometry experiments for immune cell phenotyping and functional assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design, optimize, and troubleshoot experimental protocols and SOPs, proactively identifying bottlenecks and opportunities to improve throughput, reliability, or efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Maintain rigorous documentation of protocols, experimental conditions, results, and reagent inventory and take ownership of lab operations logistics including ordering and cataloging.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Master\u0026#39;s degree in biology, immunology, molecular biology, or a related field with 2-4 years of hands-on research experience, or a Bachelor\u0026#39;s with equivalent additional experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in core molecular biology and cell engineering workflows, including bacterial culture, plasmid cloning, mammalian cell line maintenance, and lentiviral production, with the ability to troubleshoot\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with flow cytometry, including sample preparation and instrument operation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong organizational skills and attention to detail across multi-step, multi-day experimental workflows — including documentation, reagent management, and coordination.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A proactive, ownership-oriented approach — you identify bottlenecks, propose solutions, and communicate clearly in a collaborative, cross-functional environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Nice to have:\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with next-generation sequencing library preparation or single-cell genomics platforms (particularly 10x Genomics).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with T cell biology, TCR biology, or high-throughput screening assays.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Basic programming skills (Python and/or R) for data processing and QC.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Chicago, IL base pay range for a new hire in this role is $70,000 - $73,950. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a onsite position requiring you to be onsite for at least 100% of the working month, approximately 5 days a week.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":305998,"name":"Platform","child_ids":[],"parent_id":305996}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7747517","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3397432,"location":{"name":"New York, NY (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Artificial Intelligence","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will have the opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science.","value_type":"long_text"}],"id":7747517,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1644","title":"Research Engineer, AI","company_name":"Biohub","first_published":"2026-04-08T00:33:29-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world\u0026#39;s leading biologists. We\u0026#39;re not a startup trying to find product-market fit, and we\u0026#39;re not a pharma company optimizing a pipeline. We\u0026#39;re building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our research spans:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Imaging foundation models trained across the world\u0026#39;s largest microscopy datasets\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Reasoning and agentic systems that connect frontier LLMs with biological foundation models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Join Our Team!\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As a Research Engineer, you\u0026#39;ll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build on and advance the AI systems at the frontier of biology to accelerate science\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design novel model architectures and scale pre-training pipelines for our biology foundation models.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build post-training systems that drive biological discovery: RL, reward modeling, reasoning, and multi-agent orchestration for long-horizon scientific tasks.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design evaluation frameworks and AI systems with scientists across Biohub and beyond, grounded in real biological outcomes and real world impact.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Engage the wider scientific community through impactful publications, open-source releases, and collaborations worldwide.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Significant experience building and scaling deep learning systems, ideally in research-driven environments\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong engineering and scientific fundamentals\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Comfort with ambiguity, rapid iteration, and loosely-defined research problems\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong communication skills across technical and scientific audiences\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is $214,000 to $375,000 annually. Final compensation is based on the level at which you are hired. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Please note that applying to this opportunity does not guarantee that we will be in touch with you regarding our opportunities. Our recruiting team will contact you if your experience aligns with the skills we seek for future open positions. We will keep your interest on file, contact you as opportunities arise, and send you information about the exciting work we are doing at Biohub. You can opt out at any time!\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347397,"name":"AI Research","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7793665","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3397432,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Artificial Intelligence","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will have the opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science.","value_type":"long_text"}],"id":7793665,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1644","title":"Research Engineer, AI","company_name":"Biohub","first_published":"2026-04-08T17:09:43-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world\u0026#39;s leading biologists. We\u0026#39;re not a startup trying to find product-market fit, and we\u0026#39;re not a pharma company optimizing a pipeline. We\u0026#39;re building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our research spans:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Imaging foundation models trained across the world\u0026#39;s largest microscopy datasets\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Reasoning and agentic systems that connect frontier LLMs with biological foundation models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Join Our Team!\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As a Research Engineer, you\u0026#39;ll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build on and advance the AI systems at the frontier of biology to accelerate science\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design novel model architectures and scale pre-training pipelines for our biology foundation models.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build post-training systems that drive biological discovery: RL, reward modeling, reasoning, and multi-agent orchestration for long-horizon scientific tasks.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design evaluation frameworks and AI systems with scientists across Biohub and beyond, grounded in real biological outcomes and real world impact.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Engage the wider scientific community through impactful publications, open-source releases, and collaborations worldwide.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Significant experience building and scaling deep learning systems, ideally in research-driven environments\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong engineering and scientific fundamentals\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Comfort with ambiguity, rapid iteration, and loosely-defined research problems\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong communication skills across technical and scientific audiences\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is $214,000 to $375,000 annually. Final compensation is based on the level at which you are hired. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Please note that applying to this opportunity does not guarantee that we will be in touch with you regarding our opportunities. Our recruiting team will contact you if your experience aligns with the skills we seek for future open positions. We will keep your interest on file, contact you as opportunities arise, and send you information about the exciting work we are doing at Biohub. You can opt out at any time!\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347397,"name":"AI Research","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7747518","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3397433,"location":{"name":"New York, NY (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Artificial Intelligence","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will have the opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science.","value_type":"long_text"}],"id":7747518,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1642","title":"Research Scientist, AI","company_name":"Biohub","first_published":"2026-04-08T00:34:24-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world\u0026#39;s leading biologists. We\u0026#39;re not a startup trying to find product-market fit, and we\u0026#39;re not a pharma company optimizing a pipeline. We\u0026#39;re building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our research spans:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Imaging foundation models trained across the world\u0026#39;s largest microscopy datasets\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Reasoning and agentic systems that connect frontier LLMs with biological foundation models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Join Our Team!\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As a Research Scientist, you\u0026#39;ll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build on and advance the AI systems at the frontier of biology to accelerate science\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design novel model architectures and scale pre-training pipelines for our biology foundation models.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build post-training systems that drive biological discovery: RL, reward modeling, reasoning, and multi-agent orchestration for long-horizon scientific tasks.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design evaluation frameworks and AI systems with scientists across Biohub and beyond, grounded in real biological outcomes and real world impact.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Engage the wider scientific community through impactful publications, open-source releases, and collaborations worldwide.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;PhD in computer science or a related field, or equivalent experience\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Significant experience building and scaling deep learning systems, ideally in research-driven environments\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong engineering and scientific fundamentals\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Comfort with ambiguity, rapid iteration, and loosely-defined research problems\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong communication skills across technical and scientific audiences\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is $214,000 to $375,000 annually. Final compensation is based on the level at which you are hired. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Please note that applying to this opportunity does not guarantee that we will be in touch with you regarding our opportunities. Our recruiting team will contact you if your experience aligns with the skills we seek for future open positions. We will keep your interest on file, contact you as opportunities arise, and send you information about the exciting work we are doing at Biohub. You can opt out at any time!\u0026amp;nbsp;\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347397,"name":"AI Research","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7793644","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3397433,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Artificial Intelligence","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will have the opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science.","value_type":"long_text"}],"id":7793644,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1642","title":"Research Scientist, AI","company_name":"Biohub","first_published":"2026-04-08T17:01:09-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world\u0026#39;s leading biologists. We\u0026#39;re not a startup trying to find product-market fit, and we\u0026#39;re not a pharma company optimizing a pipeline. We\u0026#39;re building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our research spans:\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Imaging foundation models trained across the world\u0026#39;s largest microscopy datasets\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Reasoning and agentic systems that connect frontier LLMs with biological foundation models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Join Our Team!\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;As a Research Scientist, you\u0026#39;ll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build on and advance the AI systems at the frontier of biology to accelerate science\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design novel model architectures and scale pre-training pipelines for our biology foundation models.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Build post-training systems that drive biological discovery: RL, reward modeling, reasoning, and multi-agent orchestration for long-horizon scientific tasks.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Design evaluation frameworks and AI systems with scientists across Biohub and beyond, grounded in real biological outcomes and real world impact.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Engage the wider scientific community through impactful publications, open-source releases, and collaborations worldwide.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;PhD in computer science or a related field, or equivalent experience\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Significant experience building and scaling deep learning systems, ideally in research-driven environments\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong engineering and scientific fundamentals\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Comfort with ambiguity, rapid iteration, and loosely-defined research problems\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong communication skills across technical and scientific audiences\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is $214,000 to $375,000 annually.\u0026amp;nbsp;Final compensation is based on the level at which you are hired. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Please note that applying to this opportunity does not guarantee that we will be in touch with you regarding our opportunities. Our recruiting team will contact you if your experience aligns with the skills we seek for future open positions. We will keep your interest on file, contact you as opportunities arise, and send you information about the exciting work we are doing at Biohub. You can opt out at any time!\u0026amp;nbsp;\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347397,"name":"AI Research","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7804331","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3409762,"location":{"name":"Chicago, IL (Onsite)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Chicago"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will lead the design and development of miniaturized sensing systems for wearable and implantable medical devices. This person will play a critical role in translating early-stage prototypes into robust, manufacturable products by driving the mechanical design of housings, connectors, enclosures, microdevice assemblies, and packaging solutions.","value_type":"long_text"}],"id":7804331,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1670","title":"Senior Mechanical Engineer, Miniaturized Sensing Platforms","company_name":"Biohub","first_published":"2026-04-21T01:08:46-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Diagnostics team develops next-generation sensing technologies for real-time molecular monitoring in living systems. We bring together engineers, chemists, biologists, and translational scientists to create wearable and implantable platforms that enable high-impact applications in healthcare, therapeutics, and disease monitoring.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a Senior Mechanical Engineer to lead the design and development of miniaturized sensing systems for wearable and implantable medical devices. This person will play a critical role in translating early-stage prototypes into robust, manufacturable products by driving the mechanical design of housings, connectors, enclosures, microdevice assemblies, and packaging solutions.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a highly cross-functional role that sits at the intersection of engineering, biology, materials science, and product development. The engineer will work closely with scientists and external manufacturing partners to develop compact, high-performance sensing systems that can operate reliably in demanding biological environments.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead the mechanical design and development of wearable, implantable, and miniaturized sensing platforms for biomedical applications\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and prototype components, connectors, enclosures, fixtures, and packaging solutions for sensor systems and associated electronics\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Work closely with multidisciplinary teams to integrate mechanical, electrical, biological, and materials requirements into a manufacturable product\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with external vendors and manufacturing partners to source, fabricate, and refine high-precision components and assemblies\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Conduct prototyping, testing, failure analysis, and design optimization to improve reliability, manufacturability, and long-term device performance\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in Mechanical Engineering, Biomedical Engineering, Materials Engineering, or a related discipline\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;At minimum 2+ years of professional experience\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong industrial experience in medical device development, preferably involving wearable devices, implantable systems, or miniaturized sensing technologies\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in CAD tools such as SolidWorks, Creo, or Fusion 360 and experience designing precision mechanical systems\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with medical-grade materials, hydrogels, soft materials, connectors, packaging, and biocompatible assemblies\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong communication skills and experience working with external vendors, contract manufacturers, and multidisciplinary technical teams\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Chicago, IL base pay range for a new hire in this role is $162,000 - $171,700. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a onsite position requiring you to be in office approximately 5 days a week.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287571,"name":"CZ Biohub Chicago, LLC","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7827049","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3415856,"location":{"name":"San Francisco, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Research Groups","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub San Francisco"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will design, develop, and maintain automated protocols that support cell biology research programs.","value_type":"long_text"}],"id":7827049,"updated_at":"2026-06-05T17:01:45-04:00","requisition_id":"R1676","title":"Senior R\u0026D Engineer, Lab Automation Applications Engineer ","company_name":"Biohub","first_published":"2026-04-28T14:05:26-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub is leading the new era of AI-powered biology to cure or prevent disease through its 501c3 medical research organization, with the support of the Chan Zuckerberg Initiative.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Within Biohub, Bioengineering is a team of engineers with a diverse set of skills, including electronics, optics, imaging, automation, mechatronics, fluidics, software development, etc. We design and build custom instrumentation and automation systems to support the Biohub’s scientific mission.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We are seeking an experienced Lab Automation Applications Engineer to design, develop, and maintain automated protocols that support cell biology research programs. This role is ideal for an automation professional who can independently lead protocol development projects, optimize workflows, and serve as a technical resource for researchers. You will work closely with research scientists, hardware and software engineers, data scientists, laboratory staff, and facility managers to develop automation protocols that enhance throughput, reproducibility, and data quality. In this role, you will take ownership of end-to-end automation protocols, from initial method development through validation, production deployment, quality control and performance monitoring. You will also help drive continuous improvement of our automation capabilities.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead the design, development, testing, and validation of automated protocols for cell biology (including multi-day cell culture and passaging), cell imaging, and molecular biology.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Independently program and optimize methods on Hamilton STAR/Vantage platforms using VENUS software, and other platforms, such as Opentrons and Agilent Bravos.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with research scientists and technology teams to scope automation protocols, define requirements, and deliver solutions that meet scientific and throughput goals.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and maintain robust quality control processes for automated workflows, including run validation, error handling, and performance monitoring.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Create and maintain comprehensive documentation including method specifications, SOPs, validation reports, and training materials.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Troubleshoot and resolve, in collaboration with hardware and software engineers and/or scientists, complex hardware, software, and method issues.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manage vendor relationships for maintenance and support.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mentor junior automation engineers and contribute to the team\u0026#39;s technical growth and best practices.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify and implement process improvements that increase throughput, reliability, and data quality across the automation platform.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Essential\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor\u0026#39;s degree in Engineering, Biology, Biochemistry, or related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;5+ years of hands-on experience with laboratory automation in a biology research or industrial biotech environment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated expertise programming and running automated liquid handling systems. Experience with Hamilton STAR and Vantage liquid handlers and the VENUS software are a big plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with robotic arms, robot programming, PLC systems, or motion control\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience integrating liquid handlers with peripheral lab instruments and scheduling systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in Python or another scripting language for automation support, data analysis, or custom tooling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong understanding of molecular biology, biochemistry, and cell biology laboratory techniques.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to independently manage projects from concept through deployment.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience with proper documentation of protocols and operating procedures, performance/quality control metrics, etc.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Commitment to reproducible research practices and rigorous documentation\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to think creatively and work independently.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent problem-solving skills and the ability to quickly adapt to new technological challenges and troubleshoot complex technical problems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Eager to learn new methods, protocols and technologies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong communication and interpersonal skills.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Highly collaborative spirit and strong teamwork skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Nice to Have\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience with live cell imaging\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with laboratory data management systems (e.g., LIMS, ELN)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of data analysis, statistical methods, and workflow management software\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The San Francisco, CA base pay range for a new hire in this role is\u0026amp;nbsp;$190,000.00 - $261,800.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":304663,"name":"R\u0026D","child_ids":[],"parent_id":304662}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7767734","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3401646,"location":{"name":"New York, NY (Hybrid); Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Engineering","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub New York","CZ Biohub San Francisco"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"As a data engineer at Biohub, you'll be designing systems that ingest data from public repositories, transform heterogeneous biological formats into AI-ready datasets, combine that with proprietary datasets, and deliver training datasets to researchers pushing the boundaries of what's possible in biological AI. The infrastructure you build will directly shape what our models can learn.","value_type":"long_text"}],"id":7767734,"updated_at":"2026-06-03T13:10:09-04:00","requisition_id":"R1649","title":"Senior / Staff Data Engineer","company_name":"Biohub","first_published":"2026-03-30T21:22:33-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The role is part of the Data Engineering team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub\u0026#39;s experimental platforms to AI systems. The data that trains biological frontier models comes in dozens of modalities (sequences, images, spatial coordinates, time series, molecular structures, metadata, publication artifacts) each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a data engineer at Biohub, you\u0026#39;ll be designing systems that ingest data from public repositories, transform heterogeneous biological formats into AI-ready datasets, combine that with proprietary datasets, and deliver training datasets to researchers pushing the boundaries of what\u0026#39;s possible in biological AI. The infrastructure you build will directly shape what our models can learn.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We\u0026#39;re a small team with significant resources and long time horizons. We use AI tools aggressively in our own work—Claude Code, agents for workflow automation, LLMs for metadata extraction. We care about code quality, operational reliability, and building systems that scale. And we care about the biology: we want engineers who can recognize when a pipeline output is technically correct but scientifically wrong.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;If you want to work at the intersection of large-scale infrastructure and frontier science, with real autonomy and the chance to build something genuinely new, we\u0026#39;d like to talk.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and build data pipelines that process genomic and imaging data at petabyte scale\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Solve performance and bandwidth challenges with creative engineering\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build agent-based systems for automated dataset curation, quality control, and workflow generation\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Create tooling for data cataloging and registration that makes datasets discoverable and accessible\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with AI Research teams to translate model requirements into data specifications, and with our scientists to integrate public and internal data into large-scale ai-ready datasets\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Improve pipeline reliability and observability, working toward 99%+ success rates without manual intervention\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;8+ years experience building reliable, operable data systems at scale (100s terabytes to petabytes)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong software engineering fundamentals\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience deploying distributed computing frameworks like Databricks, Spark, or Ray for large-scale data processing\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with cloud infrastructure (AWS preferred) and HPC environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfort with ambiguity; ability to make progress when requirements are evolving\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Interest in AI-native development practices and tooling\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Nice to have: Background in computational biology, bioinformatics, or life sciences and experience with genomics datasets and formats (FASTQ, BAM, VCF) or imaging formats (OME-Zarr, HDF5)\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;br\u0026gt;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;div id=\u0026quot;message-list_1776970235.934109\u0026quot;\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;\n\u0026lt;div\u0026gt;The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is \u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;$241,000–$338,000\u0026lt;/span\u0026gt; annually. Compensation ranges will vary based on job-related skills, level of experience, and knowledge. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;/div\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid #LI-Onsite\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":290629,"name":"Data - Sci","child_ids":[],"parent_id":39963}],"offices":[{"id":287573,"name":"CZ Biohub NY, LLC","location":null,"child_ids":[],"parent_id":null},{"id":287577,"name":"Redwood Shores","location":null,"child_ids":[],"parent_id":287574}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7688757","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3380797,"location":{"name":"New York, NY (Hybrid); Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Data","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will operate with broad scope and high autonomy, influencing roadmap decisions across teams, and mentoring senior individual contributors.","value_type":"long_text"}],"id":7688757,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1625","title":"Sr Staff Data Scientist, Virtual Biology Initiative","company_name":"Biohub","first_published":"2026-05-12T18:45:49-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Biohub\u0026#39;s data organization is responsible for producing biologically informative, petabyte-scale, AI-ready datasets for frontier models of cell biology. Our work spans genomics, imaging, and proteomics, and we\u0026#39;re building the data systems that will enable a new generation of biological AI. The team consists of data engineering, data science, and technical program management. We operate with a flat structure that emphasizes strong IC ownership. We\u0026#39;re solving hard problems at the intersection of scientific strategy, large-scale data infrastructure, and foundation model training.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;In April 2026, Biohub launched the Virtual Biology Initiative—a $500 million, five-year commitment to galvanize a global effort to build predictive models of the human cell. This initiative will bring together leading institutions to generate the multi-modal biological data, at unprecedented scale, that will power the next generation of AI models for biology while producing datasets of unprecedented size.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our data science team defines the algorithms and processing approaches that turn raw biological measurements into rich representations models can actually learn from. That includes designing data formats and representations optimized for AI use cases, building cost-aware processing pipelines that balance expressiveness with efficiency, developing scalable QC and validation frameworks across modalities, creating agent-augmented curation tools for metadata extraction and ontology mapping, and building the cross-modal entity resolution and semantic infrastructure that ties it all together.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Both the scale and domain are active research areas. How do you tokenize a cell image? How do you represent a perturbation experiment? How do you combine transcriptomics with imaging in a way that preserves biological meaning? These questions don\u0026#39;t have established answers. We need scientific leaders who can work at this frontier: people who understand biological measurement deeply, think creatively about data representations, sampling, and tokenization strategies, and can translate that thinking into data representations that enable novel training architectures.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You\u0026#39;ll work directly with scientists, computational biologists, data engineers, and AI researchers to define model input and biological evaluations. You will operate with broad scope and high autonomy, influencing roadmap decisions across teams while mentoring senior individual contributors. Success in this role means creating and implementing data systems that are not only large, but adaptive, interpretable, and scientifically grounded—accelerating progress toward robust biological frontier models and ultimately advancing human health.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Set technical vision and strategy for the design of data representations and tokenization strategies across biological data types—including imaging, sequencing, and multimodal data—that enable novel model architectures\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop, deploy and validate approaches for combining heterogeneous data modalities into unified training frameworks, designing for robustness to noise, bias, and batch effects\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate model performance, identifying which biological signals are captured or lost and iterating to improve\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner deeply with ML engineers and AI researchers to co-design datasets and optimize model training, evaluation, and generalization\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead cross-functional initiatives spanning data engineering, infrastructure, science, and product, aligning technical execution with long-term scientific goals\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify and drive new data acquisition and generation opportunities, from consortium partnerships to internal experimental pipelines\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as a technical mentor and leader, raising the bar for data science and ML rigor across the organization\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;12+ years of experience (or PhD + 7 years) working with large-scale biological datasets, including ownership of end-to-end data products\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise in at least one of: (a) imaging data—microscopy, cell phenotyping, spatial biology, and the data characteristics of image-based biological measurement; or (b) genomics data—bulk and single-cell sequencing, functional genomics, epigenomics, transcriptomics, spatial biology, and/or multi-omics\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understanding of how to transform raw biological data into AI-ready datasets, including familiarity with scientific best practices, noise characteristics, batch effects, and quality assessment specific to your domain\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with tokenization strategies for non-text data (images, sequences, graphs, time series) or with creating data representations and feature engineering for machine learning in scientific or biological contexts\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong expertise in data science and statistical modeling; familiarity with modern ML architectures (transformers, diffusion models, or similar) and how data representation choices affect learning\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong computational skills; demonstrated ability to design robust, extensible data architectures\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication and leadership skills, with the ability to translate between biology, ML, and engineering audiences and align teams to deliver complex projects\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Creative, first-principles thinking about how to structure data for learning\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Redwood City, CA\u0026amp;nbsp; \u0026amp;amp;\u0026amp;nbsp; New York City, NY\u0026amp;nbsp; base pay range for a new hire in this role is $241,000.00 - $331,100.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":290629,"name":"Data - Sci","child_ids":[],"parent_id":39963}],"offices":[{"id":58664,"name":"Chan Zuckerberg Initiative","location":"Redwood City, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7775820","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3401797,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Artificial Intelligence","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You’ll own reliability, observability, and incident response for our AI research Clusters — multi-site GPU clusters running Slurm/Sunk on Kubernetes. You will build resilient AI Clusters and be the last line of defense when production hero runs are at risk.","value_type":"long_text"}],"id":7775820,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1648","title":"Staff AI Infrastructure Engineer","company_name":"Biohub","first_published":"2026-04-02T15:24:46-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The AI Cluster Production Engineering team is part of the AI Compute Platform organization at Biohub, a non-profit research lab committed to open science and open-source AI. We own the design, operation, and reliability of large-scale multi-GPU AI clusters that power frontier AI biology research: protein language models, genomic foundation models, and scientific reasoning systems built to be shared, not monetized. Our clusters run Slurm on Kubernetes infrastructure and support everything from day-to-day AI researcher workflows to multi-node hero training runs at thousands of GPUs. The team works at the intersection of AI tooling, distributed systems, HPC, and frontier AI, debugging deep AI infrastructure problems and building AI systems critical to the entire AI organization.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;CZ Biohub\u0026#39;s mission is to cure or prevent all human disease. Achieving that requires training frontier-scale AI biology models, and that demands reliable, high-performance compute infrastructure. This is production engineering work at a frontier AI lab, with the twist that the mission is biology and the science is open. You\u0026#39;ll keep GPU clusters running at high utilization, debug the toughest distributed systems failures, and build the operational foundations for scaling to multi-thousand GPU hero runs.\u0026amp;nbsp; The technical problems are genuinely hard (e.g., multi-node distributed training, InfiniBand fabrics, large-scale storage, Slurm at scale) inside an organization where the work is aimed at helping people, not optimizing ad revenue.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Own reliability, observability, and incident response for multi-site GPU clusters running Slurm on Kubernetes. Build the systems, automation, and processes that keep clusters healthy,\u0026amp;nbsp; and that enable fast, efficient recovery when things break.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Debug and resolve deep infrastructure failures across storage, networking, scheduling, and GPU compute layers. Build the tooling and operational patterns that make these failures easier to detect, diagnose, and prevent.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and execute GPU cluster scaling plans, systematically validating storage, networking, interconnect, and scheduler behavior as clusters grow to support larger training runs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build automation and tooling to manage cluster operations at scale: capacity planning, GPU utilization monitoring workload manager policy management, and pod lifecycle automation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive configuration-as-code practices, ensuring cluster state is reproducible and auditable, and managed through version-controlled pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate directly with AI researchers and hero run leads to understand training workload patterns and design infrastructure that meets frontier-scale requirements.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Own the vendor relationship on technical issues — escalating SEV1s, coordinating across multiple partners and network backbone teams, holding them accountable to root/proximate cause analysis and SLAs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to capacity planning: projecting GPU demand, managing cluster expansion across GPU generations, and coordinating multi-cluster strategy.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Improve operational resilience, reducing mean time to detect and resolve incidents, reducing toil through automation, and developing runbooks that scale the team\u0026#39;s operational knowledge beyond any individual.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;8+ years of AI/ML infrastructure engineering experience, with deep expertise in at least one of: HPC/Slurm cluster operations, Kubernetes at scale, distributed systems debugging, or GPU compute infrastructure.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong Linux systems fundamentals — networking (TCP/IP, InfiniBand, RDMA, MTU/MSS/PMTUD), storage (NFS, VAST, WEKA, POSIX semantics), kernel internals (cgroups, namespaces, eBPF, sysctls).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands-on experience with Kubernetes and cloud-native infrastructure — pod lifecycle, CNI plugins (Cilium preferred), StatefulSets, Helm, ArgoCD, or equivalent GitOps tooling.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with HPC workload managers — Slurm strongly preferred (QoS, partitions, preemption, accounting, Sunk/CoreWeave patterns a plus).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Debugging instinct: ability to form hypotheses quickly, design controlled experiments, and root cause complex multi-system failures under pressure. You enjoy finding the hard bugs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in Python and Bash for automation and tooling. Go, Rust, or C/C++ a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience with observability stacks — Prometheus/VictoriaMetrics, Grafana, DCGM metrics, distributed tracing. You know how to instrument systems you don\u0026#39;t control.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication — you can write a crisp incident summary for researchers, a technical escalation to a vendor CTO, and a system design doc for teammates, all in the same day.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Bonus: experience with distributed AI training infrastructure (NCCL, PyTorch DDP, multi-node job debugging, checkpoint/restart patterns, container environments for large-scale training).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Redwood City, CA base pay range for a new hire in this role is $241,000 - $331,000\u0026lt;strong\u0026gt;.\u0026lt;/strong\u0026gt; New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347394,"name":"AI Compute Platform","child_ids":[],"parent_id":39963}],"offices":[{"id":58664,"name":"Chan Zuckerberg Initiative","location":"Redwood City, California, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7488689","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3322572,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Data","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["Science"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will operate with broad scope and high autonomy, influencing roadmap decisions across teams, and mentoring senior individual contributors.","value_type":"long_text"}],"id":7488689,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1563","title":"Staff Data Scientist, Genomics ","company_name":"Biohub","first_published":"2026-03-10T13:50:37-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology — developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;This is an opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health — advancing frontier AI research, accelerating engineering velocity, connecting rich biological data to AI systems, enabling reliable compute across environments, and translating models and data into usable, scalable applications that drive scientific impact.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The role is part of the Data team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. We\u0026#39;re a small team with significant resources and long time horizons. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub\u0026#39;s experimental platforms to AI systems. The data that trains biological frontier models comes in dozens of modalities (sequences, images, spatial coordinates, time series, molecular structures, metadata, publication artifacts) each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We’re looking for a data scientist with deep expertise in genomics (e.g., bulk and single-cell sequencing, functional genomics, CRISPR screens), who thinks creatively about data representation and tokenization, and can translate that thinking into novel training architectures. You’ll work across experimental, computational, and AI teams to build scalable, interpretable genomic data systems that power next-generation biological models and accelerate human health discovery. You will operate with broad scope and high autonomy, influencing roadmap decisions across teams, and mentoring senior individual contributors. Success in this role means scaling data systems that are not only large, but adaptive, interpretable, and scientifically grounded, accelerating progress toward robust biological frontier models and ultimately advancing human health.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Set technical vision and strategy for the design of data representations and tokenization strategies for diverse biological data types that enable novel model architectures.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define data standards and quality metrics that enable reliable cross-dataset integration and model-ready data products.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and validate approaches for combining heterogeneous data modalities into unified training frameworks, designing for robustness to noise, bias, and batch effects\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate how representation choices impact model performance, identifying which biological signals are captured or lost and iterating to improve\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner deeply with ML engineers and AI researchers to co-design datasets and feedback loops that optimize model training, evaluation, and generalization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead cross-functional initiatives spanning data engineering, infrastructure, science, and product, aligning technical execution with long-term scientific goals.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify and drive new data acquisition and generation opportunities, from external collaborations to internal experimental pipelines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as a technical mentor and leader, raising the bar for data science and ML rigor across the organization.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;PhD in computational biology, bioinformatics, or a quantitative biological field\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ years of experience working with large-scale biological datasets (genomics, epigenomics, transcriptomics, proteomics, or multi-omics), including ownership of end-to-end data products.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep understanding of biological measurement types (sequencing, imaging, proteomics, or related), their underlying data characteristics, and how to transform raw data into ai-ready datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience designing data representations or feature engineering for machine learning in biomedical contexts\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong computational skills (Python, scientific computing libraries); Demonstrated ability to design robust, extensible data architectures and to evolve standards in fast-moving scientific domains.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong expertise in machine learning and statistical modeling, with experience applying these methods to data quality assessment, automation, or decision-making systems. Familiarity with modern ML architectures (transformers, diffusion models, or similar) and how data representation choices affect learning\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication skills, with the ability to translate between biology, ML, and engineering audiences.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Creativity, Curiosity, scientific judgment, and a willingness to engage deeply with new biological domains and emerging AI paradigms.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Redwood City, CA\u0026amp;nbsp; base pay range for a new hire in this role is $214,000 - $294,800. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":290629,"name":"Data - Sci","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7685640","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3379171,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Data","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["Science"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will operate with broad scope and high autonomy, influencing roadmap decisions across teams while mentoring senior individual contributors.","value_type":"long_text"}],"id":7685640,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1626","title":"Staff Data Scientist, Imaging","company_name":"Biohub","first_published":"2026-03-10T13:48:05-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;This role is part of the Data team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub\u0026#39;s experimental platforms to AI systems.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The data that trains biological frontier models comes in dozens of modalities—sequences, images, spatial coordinates, time series, molecular structures, metadata, preprints and published papers—each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will operate with broad scope and high autonomy, influencing roadmap decisions across teams while mentoring senior individual contributors. Success in this role means scaling data systems that are not only large, but adaptive, interpretable, and scientifically grounded, accelerating progress toward robust biological frontier models and ultimately advancing human health.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We\u0026#39;re looking for data scientists who can work at this frontier: people who understand biological measurement deeply, think creatively about data representations and tokenization strategies, and can translate that thinking into novel training architectures. You\u0026#39;ll work directly with experimental and computational scientists, data scientists and\u0026amp;nbsp; AI researchers to define what the models see and how they see it, and data engineers to make this work at scale. This is a role for someone who wants to invent the methods that make biological frontier models possible.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\n\u0026lt;p\u0026gt;Design data representations and tokenization strategies for imaging data that enable novel model architectures\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\n\u0026lt;p\u0026gt;Coordinate Experimental, Data Science, Data Engineering and AI Research teams to translate biological structure into learnable representations—defining priorities and appropriate structures for metadata and data that information models can access and consume\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\n\u0026lt;p\u0026gt;Work across those teams to guide data acquisition priorities, define quality criteria, and assess external datasets from a representation perspective\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\n\u0026lt;p\u0026gt;Develop and validate approaches for combining heterogeneous data modalities into unified training frameworks, designing for robustness to noise, bias, and batch effects\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\n\u0026lt;p\u0026gt;Evaluate how representation choices impact model performance, identifying which biological signals are captured or lost and iterating to improve\u0026lt;/p\u0026gt;\n\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;PhD in computational biology, bioinformatics, or a quantitative biological field\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Experience with tokenization strategies for non-text data (images, sequences, graphs, time series)\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Track record of novel methodological contributions (publications, open-source tools, or production systems)\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Familiarity with biological foundation models (ESM, scGPT, or similar)\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Deep understanding of imaging data, their underlying data characteristics, and how to transform raw data into ai-ready datasets.\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Experience designing data representations or feature engineering for machine learning, ideally in scientific or biological contexts\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Familiarity with modern ML architectures (transformers, diffusion models, or similar) and how data representation choices affect learning\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Strong computational skills (Python, scientific computing libraries); comfort working with large-scale datasets\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Creative, first-principles thinking about how to structure data for learning\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Redwood City, CA\u0026amp;nbsp; base pay range for a new hire in this role is $214,000 - $294,800. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in Biohub\u0026#39;s discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub\u0026#39;s total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":290629,"name":"Data - Sci","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7947779","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3444032,"location":{"name":"San Francisco, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Engineering","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You will build and support a hybrid HPC-AI environment with large-scale on-prem compute/storage and elastic cloud GPU clusters (Coreweave, AWS, GCP). You will architect and optimize environments for large-scale AI training and tuning, and low-latency scientific workloads.","value_type":"long_text"}],"id":7947779,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1691","title":" Staff HPC Engineer","company_name":"Biohub","first_published":"2026-05-20T18:28:25-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The HPC Engineering team is part of the AI Compute Platform organization at Biohub, a non-profit research lab committed to open science and open-source AI. We own the design, operation, and reliability of hybrid GPU AI clusters that power frontier AI biology research: protein language models, genomic foundation models, and scientific reasoning systems built to be shared. Our \u0026amp;nbsp;infrastructure \u0026amp;nbsp;supports day-to-day AI researcher workflows. The team works at the intersection of AI tooling, distributed systems, HPC, and frontier AI, debugging deep AI infrastructure problems and building AI systems critical to the entire AI organization.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;We seek a Staff HPC Engineer to help lead the evolution of our advanced computing infrastructure into a next-generation hybrid HPC and AI platform. This role will help shape strategy, architecture, and operations for high-performance computing resources — including cutting-edge GPUs, large-scale storage, and high-speed networks — while enabling transformative science through AI and machine learning at scale.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You will design, implement, and optimize a unified HPC-AI ecosystem blending on-prem Slurm-managed clusters, cloud GPU resources, and containerized environments. This hybrid environment will power everything from traditional HPC workloads to large AI training jobs, generative model development, real-time inference, and data-intensive pipelines.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The successful candidate will be a thought leader in HPC infrastructure , capable of partnering with scientists, computational biologists, and software engineers to translate complex research needs into high-impact computing solutions. You will also foster adoption of emerging AI tools, and ensure our systems can scale to meet the demands of next-generation biomedical research.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;HPC\u0026amp;nbsp; Engineering\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Build and support a hybrid HPC-AI environment with large-scale on-prem compute/storage and elastic cloud GPU clusters (Coreweave, AWS, GCP).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Architect and optimize environments for large-scale AI training and tuning, and low-latency scientific workloads.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate MLOps and model deployment pipelines into HPC infrastructure, ensuring reproducibility and efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Implement advanced resource scheduling and orchestration (Slurm, Kubernetes, SUNK) optimized for mixed HPC and AI workflows.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Operational Excellence\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Support researchers with job optimization, GPU utilization best practices, and performance tuning for AI and HPC applications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate, deploy, and maintain AI/ML software stacks (e.g., PyTorch, TensorFlow, Hugging Face, RAPIDS) and HPC toolchains.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure robust data ingest, analysis, and management capabilities for AI and HPC workloads, including integration with parallel file systems and object storage.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Collaboration \u0026amp;amp; Enablement\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Work with diverse science teams to translate research requirements into hardware/software solutions, from experimental design through publication.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Promote best practices for AI model training, validation, and deployment in shared computing environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Foster a culture of shared learning by running internal workshops on HPC-AI tooling (e.g., VS Code remote dev, containerization, MLOps workflows).\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Essential\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s or advanced degree in Computer Science, AI/ML, Data Science, Systems Engineering, or related field.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;10+ years building and managing HPC infrastructure, with significant experience integrating AI/ML workloads.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record architecting environments for large-scale GPU AI training and inference in hybrid on-prem/cloud environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise with HPC scheduling (Slurm), container orchestration (Kubernetes), and cloud GPU services.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong hands-on experience with AI frameworks (PyTorch, TensorFlow, JAX) and distributed training strategies (Horovod, DeepSpeed, Ray).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of MLOps best practices, including CI/CD for ML, model registry, experiment tracking, and performance monitoring.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exceptional ability to collaborate with multidisciplinary teams and communicate complex technical concepts clearly.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated leadership in guiding infrastructure teams, influencing organizational strategy, and fostering adoption of new technologies.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;Technical\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Advanced Linux systems administration, HPC networking (Infiniband, Ethernet), and storage systems administration (VAST Lustre, Weka and ZFS)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Cloud platform expertise (Coreweave, AWS, GCP) including GPU provisioning, storage, and networking for AI workloads.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in automation tools (Terraform, Ansible, Puppet), containerization (Docker, Singularity), and orchestration frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong experience debugging and troubleshooting hardware across the stack (network, GPU, compute and storage systems).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong scripting/programming skills (Python, Bash) and familiarity with version control (Git).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience integrating AI LLMs, AI coding assistants, and custom model development into HPC workflows.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The San Francisco, CA base pay range for a new hire in this role is for a Staff HPC Engineer 214,000–$268,000 and for a Senior Staff HPC Engineer $241,000–$300,000.\u0026lt;strong\u0026gt; \u0026lt;/strong\u0026gt;New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347394,"name":"AI Compute Platform","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7793810","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3405368,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Engineering","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network","Central"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You’ll develop and maintain the tooling and infrastructure that drives the entire data lifecycle at Biohub, from ingestion and processing to secure storage and access. Your work will directly support cutting-edge research, AI model training, and data analysis across the organization.","value_type":"long_text"}],"id":7793810,"updated_at":"2026-06-02T16:06:41-04:00","requisition_id":"R1664","title":"Staff Software Engineer, Data Infrastructure, AI Compute Platform","company_name":"Biohub","first_published":"2026-04-13T12:46:36-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Data Engineering and Infrastructure team brings AI/ML technology and Data to the table in new ways to help drive AI powered solutions that accelerate Biomedical research. We are uniquely positioned to design, build, and scale software systems to help scientists better address the myriad challenges they face. We are supporting researchers and scientists around the world by developing the capacity to apply state-of-the-art methods in artificial intelligence and machine learning to solve important problems in the biomedical sciences.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This team works on building shared tools and platforms to be used across Biohub, partnering and supporting the work of an extensive group of Research Scientists, Data Scientists, AI Research Scientists, and Computational Biologists. Members of the shared infrastructure engineering team have an impact on all of Biohub’s initiatives by enabling the technology solutions used by other engineering teams to build a frontier model and scale the feedback loop.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop and maintain the tooling and infrastructure that drives the entire data lifecycle at Biohub, from ingestion and processing to secure storage and access. Your work will directly support cutting-edge research, AI model training, and data analysis across the organization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with researchers and engineers across various domains, including genetics, imaging, and scientific literature. You\u0026#39;ll work on various use cases, from web analytics to complex model training, ensuring data accessibility and performance for teams across CZI.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and implement flexible, scalable, and performant systems to address our stakeholders’ needs, leveraging technologies like Argo Workflows, Slurm, Ray, AWS Parallel Cluster for mass-scale job processing and orchestration; Vast Data, Delta Lake, Databricks and Apache Iceberg for data management and access; and cloud and on-prem HPC resources\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Education \u0026amp;amp; Experience:\u0026lt;/strong\u0026gt; BS, MS, or PhD in Computer Science or a related technical discipline, or equivalent experience. 8+ years of hands-on coding experience in scripting (Python, PHP, Ruby) and systems languages (Rust, C++, C#, Go, Java, or Scala).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Data Platform Expertise: \u0026lt;/strong\u0026gt;Proficiency in managing large-scale data operations, including designing scalable pipelines (streaming and batch), working with varied data types, and optimizing flexible storage solutions using tools like Argo Workflows, Databricks, Slurm, etc.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Data Management and Development Operations:\u0026lt;/strong\u0026gt; Experience with data governance, metadata, and data lineage tooling like Open Lineage or Marquez. Deep experience working with building CI/CD pipelines for data infrastructure and associated observability and monitoring tooling such as Prometheus, Grafana, OpenTelemetry, Prometheus, or Honeycomb\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Supporting Complex Data and AI ML Workflows: \u0026lt;/strong\u0026gt;Experience with addressing end to end data needs for working with complex data and delivering this data ready form model training, working directly with AI Researchers and AI Engineers as part of AI model training project teams. Knowledge of data pipelines that feed Deep Learning model training that makes use of accelerated computing systems (GPUs as well as ASICs, FPGAs, TPUs)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Containerization: \u0026lt;/strong\u0026gt;Extensive experience with scaling containerized applications on Kubernetes or Mesos, with a focus on secure custom containers, replicability and portability.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Cloud \u0026amp;amp; Infrastructure: \u0026lt;/strong\u0026gt;Strong experience with AWS, GCP, or Azure. Exposure to hybrid environments with on-prem and colocation systems is a plus. Familiarity with Infrastructure as Code (e.g., Terraform, Ansible) and monitoring tools (Datadog, Prometheus).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026lt;strong\u0026gt;Collaboration \u0026amp;amp; Problem Solving: \u0026lt;/strong\u0026gt;Proven ability to work with diverse, cross-functional stakeholders and teams to navigate complex technical challenges, adapt to evolving requirements, and drive impactful solutions.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Redwood City, CA base pay range for a new hire in this role is $214,000 - $295,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347394,"name":"AI Compute Platform","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/biohub/jobs/7983994","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":true}],"internal_job_id":3455270,"location":{"name":"Redwood City, CA (Hybrid)"},"metadata":[{"id":167699,"name":"Careers Page - Dept.","value":"Engineering","value_type":"single_select"},{"id":176564,"name":"Careers Page - Team","value":["CZ Biohub Network"],"value_type":"multi_select"},{"id":177535,"name":"Brief Description","value":"You’ll design Secure Architecture: Architecting and implementing company wide security standards, network and system security measures such as firewalls, encryption, and Identity and Access Management (IAM) tools.","value_type":"long_text"}],"id":7983994,"updated_at":"2026-06-04T18:31:18-04:00","requisition_id":"R1701","title":"Staff Software Engineer, Security Engineering, AI Compute","company_name":"Biohub","first_published":"2026-06-04T18:24:07-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We\u0026#39;re building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Team\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Opportunity\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;The Security Engineering and Infrastructure team brings modern security engineering practices to the Biohub network to make sure our systems are secure while we accelerate Biomedical research.\u0026amp;nbsp; We are uniquely positioned to design, build, and scale software systems to help scientists better address the myriad challenges they face.\u0026amp;nbsp;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This team works on building shared tools and platforms to be used across Biohub, partnering and supporting the work of an extensive group of Research Scientists, Data Scientists, AI Research Scientists, and Computational Biologists. Members of the shared infrastructure engineering team have an impact on all of Biohub’s initiatives by enabling the technology solutions used by other engineering teams to build a frontier model and scale the feedback loop.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Do\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Designing Secure Architecture: Architecting and implementing company wide security standards, network and system security measures such as firewalls, encryption, and Identity and Access Management (IAM) tools.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Testing and Vulnerability Management: Conducting routine penetration testing and vulnerability assessments to identify and patch security gaps before attackers can exploit them.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Automating Security Processes: Scripting and deploying automated security tools, integrating scanning into CI/CD pipelines, and streamlining threat detection.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leverage and contribute to open source tools and technologies.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build observability systems to monitor performance, detect issues, debug and mitigate incidents; and participate in incident response and root cause analysis.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;What You\u0026#39;ll Bring\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;8+ years of experience in software engineering with a focus on security.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in Python and at least one systems-level language (e.g., Go, Rust, or C++).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expert knowledge across multiple domains, such as application security, cloud infrastructure, identity and access management (IAM).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to scale security beyond manual tasks\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Technical leadership and Ability to work cross functionally across the organization.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Nice to have - Experience with GPU clusters, AI/ML deployments and operations.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Compensation\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;The Redwood City, CA base pay range for a new hire in this role is $214,000 - $268,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Better Together\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager\u0026#39;s discretion and communicated during the interview process.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;h2\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(223, 22, 33); font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;color: rgb(40, 40, 39);\u0026quot;\u0026gt;\u0026lt;strong\u0026gt;Benefits for the Whole You\u0026lt;/strong\u0026gt;\u0026lt;/span\u0026gt;\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/h2\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Provides a generous employer match on employee 401(k) contributions to support planning for the future.\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Paid time off to volunteer at an organization of your choice.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Funding for select family-forming benefits.\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;Relocation support for employees who need assistance moving\u0026lt;/span\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-family: helvetica, arial, sans-serif;\u0026quot;\u0026gt;If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\u0026quot;font-weight: 400; color: #7e8c8d;\u0026quot;\u0026gt;#LI-Hybrid\u0026amp;nbsp;\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;","departments":[{"id":347394,"name":"AI Compute Platform","child_ids":[],"parent_id":39963}],"offices":[{"id":287572,"name":"CZ Biohub Network","location":null,"child_ids":[],"parent_id":null}]}],"meta":{"total":34}}