{"jobs":[{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5763048004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5033124004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5763048004,"updated_at":"2026-04-09T10:09:12-04:00","requisition_id":"632","title":"Associate Director, Clinical Data Programmer","company_name":"Amylyx Pharmaceuticals","first_published":"2026-03-05T17:02:39-05:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Clinical Data Management team at Amylyx Pharmaceuticals is seeking an Associate Director, Clinical Data Programmer. This individual will work collaboratively cross-functionally to provide hands-on data management support, programming support and technical leadership to develop, maintain, validate the clinical database, and run computer programs that access, visualize, and report clinical trial data, in accordance with various clinical plans, ICH guidelines, and applicable regulatory requirements. As an Associate Director of Clinical Data Programming, you will be required to program in the appropriate languages to create both textual and graphic displays that facilitate data cleaning and review.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead the study-specific design, development, and validation of study clinical data capture systems, ensuring data integrity, CDISC compliance and CRO oversight.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Supports leading data management activities (i.e. DMP creation, CRF creation, edit checks creation, database lock), assisting with database setup, conduct and closeout phases.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Performs UAT of systems and ensures appropriate plans and documentation are in place.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leads the development of SAS macros, data listings, summary tables and visualizations for supporting periodic and ad hoc data review.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Manages external vendor compliance and quality checks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Supports Clinical Operations, Biostatistics and Data Management by providing data insight and solving technical data challenges.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensures databases adherences to SOPs, 21CRF Part 11, ICH-GCP and CDISC Standards (CDASH/SDTM)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Acts as a subject matter expert in leading technical initiatives and data management\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree or higher in Life Science or related discipline\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ years of experience in clinical data management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Extensive experience with clinical data systems (particularly Medidata Rave) and languages like SAS, R or Python\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven experience in clinical trial programming and database management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of Clinical Data Standards such as CDISC CDASH, and SDTM\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide strong support to Data Management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience creating advanced interactive data visualizations from raw data using multi-languages and applications such as Using SAS, R, Python, RShiny, Power BI, Tableau, Spotfire etc.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to manage multiple projects simultaneously, to manage conflicting priorities, and to be flexible when priorities change.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent written and verbal communication skills and organizational and documentation skills.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested, which may include travel by air, driving or public transportation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communicate via video conference, etc.) at your remote locatio\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$183,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$206,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4052479004,"name":"313 - Biometrics","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5818910004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5059402004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5818910004,"updated_at":"2026-03-09T09:36:07-04:00","requisition_id":"644","title":"Associate Director, Computer System Validation \u0026 Quality Compliance","company_name":"Amylyx Pharmaceuticals","first_published":"2026-03-09T09:36:07-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Associate Director, Computer System Validation (CSV) \u0026amp;amp; Quality Compliance provides enterprise‑level leadership, strategic direction, and governance for the validation, lifecycle management, and continuous compliance of GxP‑relevant computerized systems, with a strong emphasis on the Veeva Quality Suite. This role ensures that digital quality solutions and supporting systems meet global regulatory requirements (FDA, EMA, ICH, GAMP 5), maintain data integrity, and enable a sustainable, inspection‑ready state across the organization.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This person will partner closely with Quality, IT, Regulatory, Clinical, and business process owners to define system requirements, lead new system implementations and major enhancements, and drive harmonized, risk‑based validation practices. This role also oversees quality compliance processes such as Change Control, Deviations, CAPA, and continuous improvement, ensuring timely closure, trend analysis, and effective governance through leadership of key forums including Quality Management Review and cross‑functional compliance meetings.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Strategic Leadership \u0026amp;amp; Governance\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Develop, evolve, and steward the corporate CSV/CSA strategy, ensuring alignment with enterprise digital strategy and Quality Management System (QMS) objectives.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as the senior Quality authority for computerized systems validation, data integrity, and electronic system compliance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee enterprise-wide governance programs, ensuring standardized, risk‑based approaches to system implementation and maintenance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide strategic guidance to senior leadership regarding system performance, risks, and compliance maturity.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Computer System Validation \u0026amp;amp; Lifecycle Oversight\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead planning, execution, review, and approval of validation deliverables across GxP systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee system lifecycle activities including impact assessments, change management, periodic reviews, audit trails, user access reviews, and system retirement.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Promote and reinforce CSA‑aligned, risk‑based validation practices to streamline compliance and maximize efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure documentation quality and consistent application of SDLC principles across projects.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Veeva Systems Expertise \u0026amp;amp; Optimization\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Serve as the Quality SME for the Veeva Quality Suite, providing expert guidance on configuration, workflow optimization, and release readiness.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead implementation, enhancement, and optimization of Veeva Vault modules and cross‑functional integrations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive automation and digitization initiatives that improve usability, compliance, and system performance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with IT and Veeva administrators to maintain robust, compliant change control processes.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Quality \u0026amp;amp; Regulatory Compliance\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Ensure all computerized systems maintain compliance with 21 CFR Part 11, EU Annex 11, GxP principles, and global data integrity expectations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Author, revise, and own Quality System policies and procedures related to electronic systems and validation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Represent Quality during internal audits, external regulatory inspections, and vendor assessments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead timely remediation, effectiveness checks, and continuous improvement initiatives.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide oversight and trending for Quality Events related to system performance or compliance.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree in a relevant scientific or technical discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;8+ years of experience in the life sciences industry with strong GxP system experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Extensive leadership experience in cross functional implementation and validation of GxP computerized systems.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise with Veeva Vault Quality Suite (QMS, Docs, Training, etc.).\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong knowledge of global regulatory expectations and data integrity frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to lead enterprise programs, influence stakeholders, and drive compliant decision making.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Preferred Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Expertise with SaaS/cloud architectures and database compliance expectations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Understanding of clinical data collection technologies and supporting data processes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with SDLC, Agile methodologies, CSV vs. CSA principles and automated testing platforms.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience developing and interpreting Quality metrics such as KPIs and KQIs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication skills with the ability to collaborate, negotiate, and influence at all organizational levels.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested, which may include travel by air, driving or public transportation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communication via video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$170,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$191,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4018294004,"name":"220 - Quality Operations","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/6002934004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5157747004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6002934004,"updated_at":"2026-05-26T16:12:32-04:00","requisition_id":"658","title":"Director, Investor Relations","company_name":"Amylyx Pharmaceuticals","first_published":"2026-05-26T11:24:10-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Join Amylyx at a pivotal moment of growth and visibility as our \u0026lt;strong\u0026gt;Director, Investor Relations\u0026lt;/strong\u0026gt;—a high-impact role at the center of our corporate story, strategy, and market presence. In this position, you’ll work side-by-side with the VP of Investor Relations \u0026amp;amp; Communications and partner closely with our senior leadership team—including our co-CEOs, CFO, CMO, and CCO—to shape how the investment community understands and values our mission.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;You’ll serve as a strategic advisor and storyteller, helping to translate complex science and financial performance into a clear, compelling narrative that resonates with investors and analysts. You’ll play a key role in strengthening our investor engagement program, building meaningful relationships, and influencing how Amylyx is perceived in a dynamic and evolving healthcare landscape.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Support the development and execution of investor relations plans and initiatives aligned with corporate goals during a period of dynamic growth, while helping to define and drive a forward-looking 12–24 month IR strategy in partnership with senior leadership and the Board, ensuring alignment with long-term corporate objectives\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Engage with the investment community, including healthcare investors and equity research analysts, represent Amylyx at events, and, over time, become a primary relationship owner for select sell-side analysts and new buy-side accounts\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Write quarterly and annual results communications, including financial results press releases, annual reports, conference call scripts, key messages, Q\u0026amp;amp;As, and other documents to communicate to investor and analyst audiences\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with colleagues to prepare documents for filings and disclosures to be compliant with SEC regulations (i.e., 8-Ks, 10-Ks, 10-Qs, proxies); in certain circumstances, lead creation of documents for filings\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Write and create investor-facing materials, including press releases, presentations for investor meetings, key message documents, Q\u0026amp;amp;As, and content for website; lead and make update as appropriate\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with leadership and other colleagues to ensure consistency of messaging\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Participate in one-on-one meetings, bus tours, conferences, and non-deal roadshows, and lead follow-up when appropriate\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Respond to requests for information from external stakeholders, including shareholders, in a timely manner\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Review and analyze analyst research and models, consensus estimates, and market-related trends impacting valuation and perception; summarize market sentiment on Amylyx and continue to manage consensus\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analyze peer companies’ communications, peer sell-side research, industry and communication trends and compile reports for leadership that support investor interactions\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with Senior IR and Communications Operations Specialist who manages active IR calendar/schedules and prepares background information on investors in advance of meetings; assist with scheduling, preparations, and investor tracking when needed\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support the overall Investor Relations function, including assisting with day-to-day needs and long-term special projects\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree required\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;10+ years of experience, including 5+ years of experience on commercial biotech or pharma team\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Background in Investor Relations, Corporate Finance, Equity Research, Buy-Side, or Consulting preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong understanding of financial modeling and how analysts assess company performance and valuation\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of SEC regulations, disclosure requirements, and management of material non-public information\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Executive presence with the ability to influence and counsel senior leaders\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Exceptional written, verbal, and presentation skills across diverse internal and external audiences\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to translate complex scientific, clinical, and financial information into clear, compelling messaging\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong understanding of investor priorities and market expectations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Sound judgment and composure in high-pressure environments\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis.\u0026amp;nbsp;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;\u0026amp;nbsp;Preference will be given to candidates who reside in the New England/NYC regions and can be in person on an as needed basis.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$204,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$230,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4076471004,"name":"531 - Investor Relations and Corp Communications","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/6002935004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5157748004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6002935004,"updated_at":"2026-05-27T10:54:46-04:00","requisition_id":"659","title":"Process Engineer","company_name":"Amylyx Pharmaceuticals","first_published":"2026-05-27T10:54:46-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Process Engineer, Drug Product, will provide technical and GMP support for contract manufacturing organizations (CMOs) responsible for late-stage clinical and commercial drug product supply. This role serves as the primary technical subject matter expert (SME) for aseptic processing including sterile filtration, formulation, filling, and container closure systems. The role will establish and maintain strong, trust-based relationships with CMO technical and quality teams to ensure reliable, compliant, and efficient manufacturing of aseptically filled drug products. Operating as a highly agile technical expert, partnering with CMOs and internal stakeholders to ensure robust execution across technology transfer, validation, and lifecycle management. This role reports to the Associate Director, CMC Drug Product.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Commercial \u0026amp;amp; Clinical Aseptic Manufacturing Support:\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Support technical leadership and day‑to‑day aseptic process engineering support for clinical and commercial drug product manufacturing at external CMOs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as the aseptic processing SME during manufacturing operations providing onsite support when required.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead investigations, perform rigorous root cause analysis and develop scientifically sound CAPAs, ensuring alignment with regulatory expectations and industry best practices.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Assess and author technical risk assessments and change controls to support manufacturing changes, investigations, and regulatory filings.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure strict compliance with cGMPs, global regulatory requirements, and internal quality systems for aseptic manufacturing.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Process Validation \u0026amp;amp; Product Launch\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead and support aseptic drug product technology transfer activities from development to clinical and commercial manufacturing sites.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define and transfer critical process parameters (CPPs), critical quality attributes (CQAs), and in‑process controls for aseptic unit operations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and execute aseptic process validation strategies, including PPQ planning, statistical sampling plans, and acceptance criteria aligned with regulatory guidance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide technical authorship and review for regulatory submissions (IND, BLA, NDA, MAA), validation reports, and responses to regulatory agency questions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support new product introductions and commercial launches by ensuring validated, scalable, and inspection‑ready aseptic processes.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Data Analysis \u0026amp;amp; Continued Process Verification\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead continued process verification (CPV) and routine data trending for aseptic unit operations, environmental monitoring, and critical process parameters.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and maintain data repositories, dashboards, and meaningful KPIs to assess aseptic process capability and performance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identify early signals of process drift or increased contamination risk and proactively drive corrective or preventive actions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prepare and present quarterly CPV summaries and technical assessments for internal management reviews.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Continuous Improvement\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Identify and execute continuous improvement initiatives focused on aseptic process robustness, sterility assurance, capacity, and operational efficiency.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Apply Quality by Design (QbD), statistical tools, and risk‑based decision making to optimize aseptic manufacturing processes.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with CMOs to implement best practices, new technologies, or process enhancements where appropriate\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree in engineering or related field with 5+ years/ Master’s with 3+ years of relevant experience.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior experience in aseptic drug product manufacturing for late-stage development/commercial is required. Device experience is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in Quality by Design (QbD), Design of Experiments (DoE), statistical process control (SPC), and complex data analysis.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Familiarity with modeling and optimization tools (e.g., MATLAB, JMP) is a plus.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Detail-oriented with strong problem-solving skills and ability to identify subtle trends in data.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comprehensive understanding of cGMP principles and regulatory requirements, including process, equipment, and facility validation.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication and teamwork skills.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to travel to domestic and international CMOs as needed.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$131,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$147,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4018288004,"name":"210 - Supply Chain","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5990836004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5151879004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5990836004,"updated_at":"2026-05-13T15:18:56-04:00","requisition_id":"656","title":"Real World Evidence/HEOR Contractor","company_name":"Amylyx Pharmaceuticals","first_published":"2026-05-07T15:12:32-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This Real World Evidence (RWE)/Health Economics (HEOR) Contractor role supports the RWE/HEOR Senior Director in leading RWE execution for pipeline assets. The role is fun and flexible with a mix of both study execution and data analytics. This person will be accountable for developing and delivering components of the evidence generation plan (including RWE and economic value evidence), and driving high-quality deliverables that inform internal decision-making during product development, pre-launch readiness, and lifecycle planning. The role is anchored to 1–2 priority pipeline assets/indications.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;This is a remote role based with flexible hours. We are currently seeking an individual with 20-30 hours of weekly availability with potential to increase hours in late 2026/2027.\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Evidence strategy and planning: Maintain US RWE \u0026amp;amp; HEOR plans for 1–2 priority pipeline assets/indications, aligned to US medical, payer, and access needs; translate strategy into actionable workplans, timelines, and resourcing proposals.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Study leadership (RWE/HEOR): Own day-to-day leadership for assigned real-world evidence and health outcomes studies (e.g., real-world evidence studies, cost-effectiveness/budget impact analyses, burden of illness, treatment patterns, patient-focused outcomes) including\u0026amp;nbsp;design and execution in partnership with internal functions and external vendors.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Scientific communication and quality: Draft/review project specifications, protocols, statistical analysis plans, study reports, abstracts, posters, and manuscripts; ensure adherence to SOPs and high scientific/operational quality.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Analytic execution and statistics: Execute ad hoc analyses in clinical trial, claims and PCOR data as needed for ad hoc and protocol/SAP driven analyses. This may include feasibility or full protocol execution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Governance, compliance, and capability building: Complete required training, adhere to company/department SOPs, and contribute to continuous improvement of processes that enable efficient planning, execution, and dissemination of RWE \u0026amp;amp; HEOR deliverables.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Master’s degree or PhD in epidemiology, health economics and outcomes research, public health, biostatistics, or related discipline.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;At least 1+ years of experience in the pharmaceutical industry and/or managed care, hospital, academic, or healthcare consulting environment with exposure to HEOR/RWE strategy and application\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency with SAS and/or R for statistical programming. Preference for experience in clinical trials OR claims data.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in RWE and study designs/methods evidenced by publications and/or contributing to study concept sheets and protocols, reviewing/authoring key sections of statistical analysis plans and study reports, and ensuring publication/disclosure readiness in accordance with ICJME criteria\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong communication and presentation skills, demonstrated by developing and presenting clear, decision-oriented materials (e.g., evidence strategy slides, executive readouts) and summarizing outcomes/next steps for senior audiences\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Preferred Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated success developing and executing health outcomes research plans and delivering high-quality data generation outputs.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience managing real-world data sources and vendors (e.g., claims, EHR, registries) and translating findings into actionable insights and value messages.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to influence without authority in a matrix environment, evidenced by aligning cross-functional stakeholders on objectives/trade-offs, documenting decisions, and driving actions to closure.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in PCOR implementation and validation\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Condition\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communication via video conference, etc.) at your remote location\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The hourly pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Contractor Hourly Compensation Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$55\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$90 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4024053004,"name":"320 - Medical Affairs","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/6002938004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5157750004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":6002938004,"updated_at":"2026-06-01T16:35:26-04:00","requisition_id":"660","title":"Senior Director, External Manufacturing","company_name":"Amylyx Pharmaceuticals","first_published":"2026-06-01T16:35:26-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Senior Director, External Manufacturing is a critical leadership role responsible for shaping and executing the external manufacturing strategy across clinical and future commercial programs. This individual will lead a global network of CDMO partners supporting a diverse and growing portfolio spanning peptides, oligonucleotides, and small molecules.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As Amylyx advances toward commercialization and expands its global manufacturing footprint, this role will be instrumental in ensuring supply continuity, operational readiness, and long-term scalability. The Senior Director will partner cross-functionally to enable successful product launches, manage increasing manufacturing complexity, and build the infrastructure needed to support future growth and global expansion.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Provide strategic leadership and oversight of external manufacturing across clinical development and commercial supply\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish and govern CDMO partnerships to ensure strong performance, accountability, and alignment with program objectives\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define and execute manufacturing strategies to support technology transfer, scale-up, commercialization, and lifecycle management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish supplier performance metrics and business review process\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mentor and build a team of relationship owners responsible for leading the internal supplier relationship teams and serving as the supplier point of contact\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure supply continuity through proactive risk identification, mitigation planning, and issue escalation across external partners\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee technology transfer, manufacturing execution, and process performance across a global network of external sites\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support commercial launch readiness, including validation, supply planning, and inspection preparedness\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner cross-functionally with Finance, Legal, CMC, Quality, and Supply Chain to drive aligned execution\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build scalable, robust external manufacturing infrastructure, operating models, and governance frameworks to support organizational growth\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree in engineering, life sciences, or related field; advanced degree preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;~15+ years of experience in pharmaceutical or biotechnology manufacturing, including significant external manufacturing leadership\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record managing CDMOs across clinical and commercial supply environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep understanding of cGMP regulations, global manufacturing requirements, and regulatory expectations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience in manufacturing strategy, technology transfer, and commercialization activities\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to lead in complex, multi-program environments and drive cross-functional alignment\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong leadership, communication, and stakeholder management skills\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior experience supporting commercial product launches, conducting RFPs, negotiating supply agreements, and managing high value budgets\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience across multiple supply nodes (API, Drug Product, Packaging, Device)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to travel domestically and internationally ~10%\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Preferred Requirements\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Experience across multiple modalities (small molecule, peptide, oligonucleotide)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;A track record of process scale-up, validation and continuous improvement\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$245,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$276,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4018288004,"name":"210 - Supply Chain","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5968719004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5141543004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5968719004,"updated_at":"2026-04-21T11:31:59-04:00","requisition_id":"653","title":"Senior Director, HRBP - Commercial","company_name":"Amylyx Pharmaceuticals","first_published":"2026-04-21T11:31:59-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Reporting to the SVP, Human Resources and Talent Acquisition, the Senior Director, HR Business Partner (HRBP) for the Commercial Organization is a strategic leadership role responsible for partnering closely with the Chief Commercial Officer (CCO) and Commercial Leadership Team to build, scale, and optimize a high-performing commercial function. This individual will serve as a trusted advisor, aligning people strategies with business objectives to support the successful transition to and execution of commercialization, including both corporate and field-based teams.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This role will be hired in advance of commercial scale-up and top-line data, within a lean and evolving organization. While the primary focus is supporting the Commercial function, the Senior Director will initially operate as a broad HR Business Partner across the enterprise, flexing support across Clinical, Technical Operations, and G\u0026amp;amp;A as needed. This role requires comfort operating in a highly dynamic, resource-constrained environment, with the ability to balance strategic leadership with hands-on execution.\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As the organization evolves through key clinical and commercial milestones, this role is expected to scale in scope and impact, transitioning from a broad, hands-on HR Business Partner role to a more dedicated commercial HR leadership position.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Strategic Partnership \u0026amp;amp; Leadership\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Serve as the primary HR partner to the CCO and Commercial Leadership Team, providing strategic counsel on organizational effectiveness, talent, and culture\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to the development and execution of the commercial strategy by aligning HR initiatives with business priorities\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Act as a thought partner on scaling the organization from pre-commercial to fully commercial operations\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Organizational Design \u0026amp;amp; Build-Out\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead the design and implementation of the commercial organizational structure, including headquarters and field-based teams (e.g., sales, market access, patient services, marketing)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support workforce planning aligned to launch readiness, market expansion, and long-term growth\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive role clarity, spans and layers optimization, and organizational efficiency\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Talent Strategy \u0026amp;amp; Development\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Partner with leadership to attract, retain, and develop top commercial talent, including building leadership capability across the organization\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Guide succession planning and leadership development initiatives\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Coach senior leaders on performance management, team effectiveness, and change leadership\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Performance \u0026amp;amp; Compensation\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with Total Rewards to design and implement competitive compensation and incentive programs aligned with commercial goals (including sales incentives and LTI structures)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Support performance management processes aligned to corporate and commercial objectives, ensuring the foundational elements of a high-performing commercial culture are in place, including clear goal-setting, accountability, and differentiated performance outcomes\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Culture \u0026amp;amp; Employee Experience\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Champion a high-performance, patient-centric culture aligned with company values\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead change management initiatives to support rapid growth and evolving business needs\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure strong employee engagement across both corporate and geographically dispersed field teams\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;Employee Relations \u0026amp;amp; Compliance\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Provide guidance on complex employee relations matters with sound judgment and business alignment\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure compliance with all applicable employment laws and company policies, particularly within a distributed field organization\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree in Human Resources, Business Administration, or related field required; Master’s degree (MBA, MS, or equivalent) strongly preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Minimum of 15+ years of progressive HR experience, including significant HR Business Partner leadership roles\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience partnering with a Chief Commercial Officer and senior commercial leadership in building and scaling commercial organizations while being willing to operate beyond a single function and support enterprise-wide needs\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven success supporting both corporate and field-based teams, including sales organizations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience within biotechnology or pharmaceutical industry required;\u0026amp;nbsp;\u0026lt;strong\u0026gt;rare disease experience strongly preferred\u0026lt;/strong\u0026gt;\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Comfortable navigating ambiguity and shifting priorities, with a willingness to take on both strategic and hands-on HR responsibilities across multiple functions\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise in organizational design, talent management, and change leadership in high-growth environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong business acumen with the ability to translate strategy into actionable HR initiatives\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis.\u0026amp;nbsp; Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$243,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$273,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4018291004,"name":"520 - HR","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5843906004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5071657004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5843906004,"updated_at":"2026-04-08T11:19:10-04:00","requisition_id":"647","title":"Senior Director, Market Access  Strategy","company_name":"Amylyx Pharmaceuticals","first_published":"2026-04-06T14:47:37-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;We are seeking a Senior Director, Market Access Strategy to support a new product launch. This leader will own the creation of the payer value proposition, lead pricing strategy for launch, and prepare effective communications across payer, distribution channel, field access, and patient support teams.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;As a key member of the Market Access leadership team, you will work cross functionally to drive strategies for all market access functions, oversee a post-launch marketing and pricing operations team, and effectively manage any vendors that support these initiatives.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Shape and lead the payer value story for Amylyx’s first launch product, translating clinical, economic, and real‑world evidence into a differentiated, evidence‑based value proposition that supports optimal access and reimbursement.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drive payer marketing and launch execution in close partnership with Medical Affairs, including development of PIE content, AMCP dossiers, and comprehensive launch education materials.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with Medical and Access leadership to define payer evidence requirements, identify data gaps, and execute strategies to address unmet needs across pre‑ and post‑launch phases.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop\u0026lt;strong\u0026gt; \u0026lt;/strong\u0026gt;and deploy access tools and communications that enable field access teams, patient support programs, and pharmacy partners to execute effectively and consistently.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish a cross‑functional performance feedback loop across payer, field access, pharmacy, and services teams to rapidly identify access barriers and drive issue resolution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build and oversee post‑launch pricing operations, including list price governance, price change management, pricing committee leadership, and close collaboration with Finance on gross‑to‑net management.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead agencies and vendors, monitor payer and policy dynamics, and represent market access strategies\u0026lt;strong\u0026gt; \u0026lt;/strong\u0026gt;including performance, risks, and opportunities—to internal stakeholders and senior leadership.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree required\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;12+ years of experience in pharmaceutical market access, pricing, reimbursement strategy, and payer marketing\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior launch experience in US market\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep expertise in the U.S. payer, reimbursement, coverage, and coding landscape for specialty products under the pharmacy benefit\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven experience developing payer value propositions and payer‑facing materials\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong analytical skills using market access data sources (e.g., HUB, specialty pharmacy, and claims data)\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;People leadership experience, including hiring, coaching, and developing teams\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated experience with pricing strategy, contract modeling, and gross‑to‑net management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong vendor management and contracting experience across agencies, consultants, analytics partners, and pricing operations vendors\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$263,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$296,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4024055004,"name":"420 - Market Access","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5849964004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5074218004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5849964004,"updated_at":"2026-04-14T09:15:10-04:00","requisition_id":"651","title":"Senior Director, Patient Services","company_name":"Amylyx Pharmaceuticals","first_published":"2026-04-06T15:40:03-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Senior Director of Patient Services will play a critical role in shaping how Amylyx supports patients throughout their treatment journey. This leader will design, build, and launch a best-in-class patient support program for our lead product candidate, ensuring that it reflects a commitment to supporting patient access, community education, and operational excellence.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This individual will bring strategic vision and hands on leadership to create an integrated support program—from access and reimbursement solutions to patient education and continued on-treatment support. As a key leader in the commercial organization, this individual will partner with colleagues across market access, sales, and marketing, as well as cross functionally, to ensure a seamless and high impact customer experience that helps people start and continue treatment.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;This is a unique opportunity to define a foundational capability at Amylyx and set a new standard for patient access support.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;u\u0026gt;Program Design\u0026lt;/u\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design a comprehensive, patient‑centered services model tailored to the unique needs of the communities we serve\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define the strategic framework, service offerings, operational workflows, and end‑to‑end experience for patients, caregivers, and providers, ensuring alignment with the current market access landscape across reimbursement, technology, and delivery models\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Optimize the program by determining the appropriate balance of insourced versus outsourced services and planning for program evolution over time\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;\u0026amp;nbsp;\u0026lt;/strong\u0026gt;\u0026lt;strong\u0026gt;\u0026lt;u\u0026gt;Operations Leadership\u0026lt;/u\u0026gt;\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead end‑to‑end patient support operations, including financial assistance, benefits verification, case management, adherence, nursing, and injection training\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build, hire, and lead high‑performing internal and field‑based patient access and service operations teams\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Evaluate, contract, and manage third‑party service providers, ensuring strong governance, performance accountability, and alignment with business objectives\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish compliant oversight across hub services and all patient‑facing operations in close partnership with Legal, Compliance, and Medical Affairs\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define KPIs, dashboards, and feedback loops to drive performance, transparency, and continuous improvement across service operations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as the operational lead for launch readiness and ongoing execution by identifying access barriers, leading cross‑functional issue resolution, and aligning with Commercial, Market Access, Sales, Medical Affairs, IT, and National Accounts teams\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree required, advanced degree in a related health or business field preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;12+ years of experience in biopharmaceutical patient support services, including product launch and rare disease product access\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven track record designing, launching, and managing hub services, reimbursement support, and financial assistance programs\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Expertise in U.S. payer specialty drug coverage, reimbursement mechanics, and specialty pharmacy operations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proficiency in analytics and reporting for service programs and pharmacy data\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Knowledge of compliance and regulatory requirements for patient support programs\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to communicate program objectives, launch plans, and performance effectively to internal stakeholders\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven people management experience, including hiring, coaching, and developing teams\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated leadership of cross‑functional teams in fast‑paced, launch‑focused environments\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;An unwavering dedication to patient access and empowering the teams responsible for delivering it\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$253,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$285,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4024055004,"name":"420 - Market Access","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5843909004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5071659004,"location":{"name":"Cambridge, MA"},"metadata":null,"id":5843909004,"updated_at":"2026-04-09T12:47:56-04:00","requisition_id":"648","title":"Senior Director, Trade \u0026 Channel Operations","company_name":"Amylyx Pharmaceuticals","first_published":"2026-04-06T14:26:59-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The Senior Director, Trade \u0026amp;amp; Channel Operations will be responsible for building Amylyx’s U.S. distribution and channel model from the ground up in preparation for a future commercial launch of our lead product candidate. This individual will architect the distribution strategy, create the operational infrastructure necessary for launch, and partner cross functionally to ensure Amylyx is fully prepared to commercialize with excellence. As a key member of the Market Access team, this role will influence launch readiness, customer service delivery, and ongoing performance across distribution partners.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and build Amylyx’s U.S. distribution model across specialty pharmacy, specialty distributor, and 3PL channels to support product launch\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Lead contracting strategy for specialty pharmacies and distributors, including negotiating distribution and service agreements, fee schedules, data requirements, and service levels\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Integrate distribution channels with service programs and field initiatives to enable a seamless customer experience\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Collaborate with Supply Chain and Finance to support 3PL operations, including order‑to‑cash processes, inventory management, data exchange, shipping, returns, and chargeback management\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish and manage noncommercial and free‑goods pharmacy operations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Forecast and model channel performance, assess specialty pharmacy throughput, and provide recommendations to ensure timely, reliable patient access\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop distribution analytics including inventory visibility, service metrics, dispense data, time to therapy, and partner scorecards; lead specialty pharmacy QBRs\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner cross‑functionally with Supply Chain, Quality, Compliance, Legal, Finance, Patient Services, and Commercial Operations to ensure operational alignment and launch readiness\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serve as a senior leader within Market Access, contributing to launch planning, forecasting, patient access workflows, and overall distribution strategy\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Continuously optimize post‑launch distribution operations by driving root‑cause remediation, vendor KPI management, and process improvements informed by field and service feedback.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree required\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;12+ years of experience in biopharmaceutical trade and distribution, including leadership of specialty pharmacy and distributor channel networks\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Prior product launch experience in the US market\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience designing and implementing channel strategies for product launches\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to assess, manage, and influence channel partner performance to contractual expectations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Hands‑on experience with 3PL operations, serialization, state licensing, and compliant distribution processes\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated strength in contract negotiation, vendor management, and commercial channel operations\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Deep understanding of payer reimbursement, hub/patient support integration, channel economics, and order‑to‑cash workflows\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven leadership experience, including managing large pharmaceutical vendors, with demonstrated people management skills\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication, vendor management, analytical, and project execution capabilities\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026amp;nbsp;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$255,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$287,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4024055004,"name":"420 - Market Access","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5600871004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":4959386004,"location":{"name":"Cambridge, MA - Remote"},"metadata":null,"id":5600871004,"updated_at":"2026-03-27T14:27:38-04:00","requisition_id":"606","title":"Senior Medical Director, Clinical Development","company_name":"Amylyx Pharmaceuticals","first_published":"2025-07-29T13:01:03-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx is seeking a Senior Medical Director, Clinical Development to provide strategic and scientific leadership for one or more late-stage, pivotal programs with the potential to expand into additional indications and/or programs within the same molecule or across the portfolio. This individual will play a critical role in shaping the overall clinical development strategy and may lead multiple programs or key components of a broader development portfolio.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Reporting to the Senior VP of Clinical Development, you will be responsible for leading the design, execution, and interpretation of clinical studies and overseeing the development and implementation of Clinical Development Plans across assigned assets. You will provide strategic input into study design, endpoints, and regulatory strategy, ensuring alignment with the overall program and corporate objectives.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The successful candidate will collaborate with cross-functional teams in a matrix environment, influencing stakeholders across Research, Regulatory Affairs, Clinical Operations, and Commercial to ensure that clinical and scientific considerations are fully integrated into development plans. You will proactively identify and mitigate risks, guide decision-making through data-driven insights, and ensure the highest standards of scientific rigor and data integrity.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;In this role, you will also serve as a key external representative, engaging with global medical experts, investigators, regulatory authorities, and alliance partners. You may lead or mentor a team of clinical scientists and physicians and contribute to broader organizational and portfolio-level initiatives.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Provides strategic medical leadership and oversight for assigned clinical programs, including late-stage and pivotal trials.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leads development and execution of Clinical Development Plans (CDPs), integrating clinical, scientific, regulatory, and commercial considerations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Drives study design, protocol development, and interpretation of complex clinical data to inform key program decisions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Serves as a core member of cross-functional program teams, influencing strategy and ensuring alignment across disciplines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provides senior-level medical monitoring and guidance, ensuring patient safety, data integrity, and high-quality trial execution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Leads interactions with external stakeholders including key opinion leaders, investigators, regulatory agencies, and alliance partners.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversees preparation of key program documents including protocols, investigator brochures, clinical study reports, regulatory submissions, and publications.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mentors and provides scientific guidance to junior team members, including Medical Directors and Clinical Scientists.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Identifies and implements process improvements and best practices within Clinical Development.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;MD required\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Significant experience in late-stage clinical development and drug development in biotech/pharmaceutical industry; rare disease experience strongly preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Typically 5+ years of experience leading clinical development programs with demonstrated impact on program strategy and execution\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated ability to collaborate with cross-functional teams and influence without authority in a matrix environment\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong strategic thinking, problem-solving, and decision-making skills\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven ability to interpret complex clinical data and translate insights into actionable strategies\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Excellent communication and leadership skills, with experience interacting with senior stakeholders and external experts\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience mentoring or leading team members preferred\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to travel internationally and domestically\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$315,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$354,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4065235004,"name":"311 - Clinical Development","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]},{"absolute_url":"https://job-boards.greenhouse.io/amylyx/jobs/5994725004","data_compliance":[{"type":"gdpr","requires_consent":false,"requires_processing_consent":false,"requires_retention_consent":false,"retention_period":null,"demographic_data_consent_applies":false}],"internal_job_id":5153848004,"location":{"name":"Flexible/ U.S. Based"},"metadata":null,"id":5994725004,"updated_at":"2026-05-22T12:40:13-04:00","requisition_id":"657","title":"Senior Vice President, Sales","company_name":"Amylyx Pharmaceuticals","first_published":"2026-05-13T12:54:43-04:00","language":"en","application_deadline":null,"content":"\u0026lt;div class=\u0026quot;content-intro\u0026quot;\u0026gt;\u0026lt;p\u0026gt;Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;The Opportunity\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The SVP of Sales will play a critical leadership role in building and executing the commercial strategy for a pre‑commercial biotechnology company preparing for its first product launch. This individual will be responsible for designing and implementing the Go‑To‑Market (GTM) strategy, recruiting and developing a high‑performing sales organization, establishing strong relationships with Key Opinion Leaders (KOLs), ensuring full sales force readiness ahead of launch and driving performance.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;em\u0026gt;\u0026lt;strong\u0026gt;We anticipate hiring the Senior Vice President, Sales in September 2026.\u0026lt;/strong\u0026gt;\u0026lt;/em\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;The ideal candidate combines strategic vision with hands‑on execution experience in specialty pharma or biotech launches and thrives in a fast‑paced, build‑from‑scratch environment.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Responsibilities\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Enterprise Commercial Leadership\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Shape overall U.S. commercial strategy in partnership with the Chief Commercial Officer, including long-range planning beyond initial launch.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Play a key role in portfolio planning and lifecycle strategy, including future indications and pipeline assets.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Contribute to Board-level discussions on commercial readiness, launch strategy, and performance.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with Finance and Executive Leadership on revenue planning, scenario modeling, and investment decisions.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Go‑To‑Market Strategy \u0026amp;amp; Execution\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Design and implement a comprehensive Go‑To‑Market plan, aligned with brand strategy, market access, patient services, medical affairs, and marketing capabilities.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Translate clinical value propositions into clear commercial messaging and field execution plans.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner cross‑functionally with Marketing, Medical Affairs, Market Access, and Operations to ensure launch readiness.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Define sales territory strategy, targeting, segmentation, and deployment models.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Establish key performance indicators (KPIs), sales forecasting processes, and performance management frameworks.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Sales Organization Build‑Out\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Recruit, hire, and onboard a high‑caliber field sales team, including regional leadership.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Design and evolve a scalable sales organization architecture, with the ability to expand across multiple teams, regions, and future product lines.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop a multi-year sales capability roadmap, including leadership bench building and succession planning.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Build and lead second-line leadership (RSDs/Area Directors) as the organization scales.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Develop and implement training programs to prepare the team for launch, including disease state education, product knowledge, and selling skills.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Create a performance‑driven culture focused on accountability, collaboration, and continuous improvement.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Launch Preparation \u0026amp;amp; Excellence\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Lead all sales‑related launch readiness activities, ensuring the field team is fully prepared for pre-launch and launch execution.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Oversee development and deployment of sales tools, CRM processes, call planning, incentive compensation and reporting infrastructure.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ensure compliance with all regulatory, legal, and ethical standards.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;KOL \u0026amp;amp; External Engagement\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Engage with Key Opinion Leaders (KOLs) and other key stakeholders to support scientific exchange and commercial insight gathering.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Partner with Medical Affairs to ensure appropriate, compliant KOL interactions.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Provide field‑based insights to inform brand strategy, messaging refinement, and lifecycle planning.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Leadership \u0026amp;amp; Stakeholder Management\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Serve as a key member of the commercial leadership team, contributing to overall business strategy.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Present sales strategy, progress, and performance updates to executive leadership and the Board as required.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Mentor and develop future sales leaders within the organization.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Required Qualifications\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;Bachelor’s degree required; advanced degree (MBA, MS, PhD) preferred.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;15+ years of progressive sales leadership experience in biotech or pharmaceutical organizations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Demonstrated success leading early product launches, ideally in specialty or rare disease.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Proven experience building and scaling sales teams in pre‑commercial or early‑stage environments.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Strong understanding of the U.S. healthcare landscape, including KOL engagement, payer dynamics, and integrated launch planning.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Experience working cross‑functionally in highly matrixed organizations.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;Ability to operate both strategically and tactically in a resource‑constrained environment.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Work Location and Conditions\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;ul\u0026gt;\n\u0026lt;li\u0026gt;At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.\u0026lt;/li\u0026gt;\n\u0026lt;li\u0026gt;You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\u0026lt;/li\u0026gt;\n\u0026lt;/ul\u0026gt;\u0026lt;div class=\u0026quot;content-pay-transparency\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;pay-input\u0026quot;\u0026gt;\u0026lt;div class=\u0026quot;description\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;Compensation\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span data-teams=\u0026quot;true\u0026quot;\u0026gt;The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\u0026lt;/span\u0026gt;\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;title\u0026quot;\u0026gt;Estimated Pay Range\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;pay-range\u0026quot;\u0026gt;\u0026lt;span\u0026gt;$353,000\u0026lt;/span\u0026gt;\u0026lt;span class=\u0026quot;divider\u0026quot;\u0026gt;\u0026amp;mdash;\u0026lt;/span\u0026gt;\u0026lt;span\u0026gt;$397,000 USD\u0026lt;/span\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;/div\u0026gt;\u0026lt;div class=\u0026quot;content-conclusion\u0026quot;\u0026gt;\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To stay connected with us, follow Amylyx Pharmaceuticals on \u0026lt;a href=\u0026quot;https://www.linkedin.com/company/amylyx\u0026quot;\u0026gt;LinkedIn\u0026lt;/a\u0026gt;. \u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;strong\u0026gt;To return to our website please \u0026lt;a href=\u0026quot;https://www.amylyx.com/\u0026quot; target=\u0026quot;_blank\u0026quot;\u0026gt;click here\u0026lt;/a\u0026gt;.\u0026lt;/strong\u0026gt;\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\u0026lt;/p\u0026gt;\n\u0026lt;p\u0026gt;It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.\u0026lt;/p\u0026gt;\u0026lt;/div\u0026gt;","departments":[{"id":4018297004,"name":"430 - Sales \u0026 Sales Training","child_ids":[],"parent_id":null}],"offices":[{"id":4009590004,"name":"United States","location":"Cambridge, Massachusetts, United States","child_ids":[],"parent_id":null}]}],"meta":{"total":12}}